Favorites 0

Home > Product > Salicylic Peel 25%

Salicylic Peel 25%

Salicylic Peel 25% Higher-intensity superficial exfoliation for professional protocols aimed at oil control, epidermal renewal and the progressive improvement of the skin's visual quality. Salicylic Peel 25% TherapDerma is a professional chemical peel formulated with 25% Salicylic Acid, belonging to the Beta Hydroxy Acid (BHA) family. It has been developed to promote a carefully controlled superficial exfoliation, intended for professionals requiring a higher-intensity cosmetic action within personalised protocols designed for the treatment of oily skin, acne-prone skin, photoaged skin or skin with superficial pigmentation irregularities. Thanks to the lipophilic nature of Salicylic Acid, this formulation exhibits a high affinity for the sebum-rich environment, promoting selective action on the pilosebaceous follicle. This characteristic helps to progressively remove accumulated corneocytes, superficial impurities and excess sebum, contributing to the refinement of skin texture, the improvement of pore appearance and a visually more even complexion. When incorporated into a properly planned professional protocol, it may contribute to the progressive improvement of the appearance of acne-prone skin, enlarged pores, uneven texture, superficial post-acne scars, photoaged skin and superficial pigmentation irregularities, while always respecting skin physiology and the individual's biological response. According to the manufacturer's technical documentation, Salicylic Peel 25% is a formulation intended for higher-intensity superficial exfoliation protocols, indicated for professionals wishing to expand the therapeutic possibilities of Salicylic Acid where there is an appropriate clinical indication. More than an isolated procedure, Salicylic Peel 25% forms part of the TherapDerma Clinical Ecosystem™, a methodology based on diagnosis, therapeutic planning, treatment personalisation and continuity of care.

Description

Salicylic Peel 25%
Higher-intensity superficial exfoliation for professional protocols aimed at oil control, epidermal renewal and the progressive improvement of the skin’s visual quality.
Salicylic Peel 25% TherapDerma is a professional chemical peel formulated with 25% Salicylic Acid, belonging to the Beta Hydroxy Acid (BHA) family. It has been developed to promote a carefully controlled superficial exfoliation, intended for professionals requiring a higher-intensity cosmetic action within personalised protocols designed for the treatment of oily skin, acne-prone skin, photoaged skin or skin with superficial pigmentation irregularities.
Thanks to the lipophilic nature of Salicylic Acid, this formulation exhibits a high affinity for the sebum-rich environment, promoting selective action on the pilosebaceous follicle. This characteristic helps to progressively remove accumulated corneocytes, superficial impurities and excess sebum, contributing to the refinement of skin texture, the improvement of pore appearance and a visually more even complexion.
When incorporated into a properly planned professional protocol, it may contribute to the progressive improvement of the appearance of acne-prone skin, enlarged pores, uneven texture, superficial post-acne scars, photoaged skin and superficial pigmentation irregularities, while always respecting skin physiology and the individual’s biological response.
According to the manufacturer’s technical documentation, Salicylic Peel 25% is a formulation intended for higher-intensity superficial exfoliation protocols, indicated for professionals wishing to expand the therapeutic possibilities of Salicylic Acid where there is an appropriate clinical indication.
More than an isolated procedure, Salicylic Peel 25% forms part of the TherapDerma Clinical Ecosystem™, a methodology based on diagnosis, therapeutic planning, treatment personalisation and continuity of care.

What makes Salicylic Peel 25% different?

Not all chemical peels are designed to achieve the same clinical objective.
Each acid possesses specific physicochemical properties that determine its affinity for different skin structures, its biological behaviour and its role within professional treatment protocols.
Salicylic Peel 25% has been developed for professionals wishing to incorporate a higher-intensity superficial exfoliation strategy aimed at oil control, epidermal renewal and the progressive improvement of the appearance of acne-prone, photoaged skin or skin with superficial pigmentation irregularities.
Its main distinguishing characteristic remains the affinity of Salicylic Acid for sebum, but this concentration makes it possible to expand clinical treatment possibilities when appropriate patient selection and correct therapeutic planning are carried out.
According to the manufacturer’s documentation, this concentration is primarily intended for professional protocols targeting:
• oily and acne-prone skin;
• photoageing;
• freckles and lentigines;
• post-inflammatory hyperpigmentation;
• enlarged pores;
• superficial acne scars;
• moderate actinic keratosis;
• seborrhoeic dermatitis.
________________________________________
What is Salicylic Acid?
Salicylic Acid is a Beta Hydroxy Acid (BHA) widely used in professional aesthetics for its superficial exfoliating capacity and its affinity for the skin’s lipid-rich environment.
Its lipophilic nature enables it to act preferentially on areas with greater sebum production, distinguishing it from Alpha Hydroxy Acids (AHAs), whose action takes place primarily on the aqueous surface of the epidermis.
When incorporated into a properly balanced professional formulation, it may contribute to:
• promoting the removal of accumulated corneocytes;
• helping to reduce excess surface oil;
• helping to keep pores cleaner;
• progressively improving the appearance of comedones;
• promoting visible epidermal renewal;
• improving the appearance of superficial skin tone irregularities;
• refining skin texture;
• promoting a visually more even and balanced complexion.
The clinical response to a chemical peel does not depend solely on the acid concentration. Factors such as the formulation pH, the vehicle used, the exposure time, the application technique and the individual biological characteristics of each patient also play an important role.
________________________________________
Positioning within the TherapDerma Clinical Ladder™
At TherapDerma, we understand that the concentration of a peel is a tool designed to adapt treatment to each patient’s specific needs rather than an isolated indicator of greater therapeutic intensity.
Each acid and each concentration correspond to different clinical objectives, specific skin profiles and different levels of action.
Within the BHA collection, Salicylic Peel 25% occupies a position intended for higher-intensity superficial exfoliation protocols aimed at:
• oil regulation;
• deep purification of the pilosebaceous environment;
• progressive pore refinement;
• improving the appearance of acne-prone skin;
• improving skin texture;
• supporting superficial photoageing protocols;
• improving the appearance of superficial hyperpigmentation;
• cosmetic treatment of superficial post-acne scars.
According to the manufacturer’s technical information, Salicylic Peel 25% represents the highest-strength BHA concentration within this range, intended for professionals requiring a more intensive superficial action where there is an appropriate clinical indication and suitable patient assessment.
The choice between the different concentrations should always be based on professional diagnosis, the individual’s biological response and the observed clinical progression.
________________________________________
TherapDerma Philosophy
At TherapDerma, we believe that the best clinical outcomes do not depend solely on the intensity of exfoliation.
They depend on understanding skin biology, establishing an accurate diagnosis and selecting the most appropriate therapeutic strategy for each patient.
The use of higher concentrations requires an even more careful assessment of the skin barrier function, phototype, skin tolerance and therapeutic objectives, allowing the development of progressive, safe and personalised protocols.
For this reason, Salicylic Peel 25% is integrated into the TherapDerma Clinical Ecosystem™, a working model that combines chemical peels, mesotherapy, medical-aesthetic technologies and home care through individualised protocols based on clinical criteria.
________________________________________
TherapDerma Conclusion
Salicylic Peel 25% is a professional tool intended for higher-intensity superficial exfoliation protocols aimed at oil control, epidermal renewal and the progressive improvement of the skin’s visual quality.
Its main value lies in combining the lipophilic affinity of Salicylic Acid with a concentration especially indicated for professionals seeking to expand therapeutic possibilities in appropriately selected skin, including superficial photoageing, hyperpigmentation, enlarged pores and superficial post-acne scars.
When integrated into an appropriate clinical treatment plan, Salicylic Peel 25% represents a professional solution designed to achieve progressive, safe and predictable results while always respecting skin physiology and the patient’s individual biological progression.

Clinical Benefits

Higher-intensity superficial exfoliation, sebum regulation and progressive improvement in the appearance of oily, acne-prone, photoaged skin or skin with superficial tone irregularities within personalised professional protocols
Salicylic Peel 25% TherapDerma has been developed to promote a higher-intensity, clinically controlled superficial exfoliation, intended for the cosmetic treatment of oily, seborrhoeic, congested, acne-prone, photoaged skin or skin with superficial pigmentation irregularities.
Thanks to the lipophilic nature of Salicylic Acid, this peel has an affinity for skin areas with a higher sebaceous content, promoting the progressive removal of accumulated corneocytes, purification of the pilosebaceous environment, control of excess oiliness and visible epidermal renewal.
When incorporated into an individualised professional protocol, its benefits develop gradually while respecting the skin barrier, skin tolerance and each patient’s specific biological response.
________________________________________
💧 Progressive regulation of excess sebum
What does it provide clinically?
Salicylic Acid helps to progressively regulate excess surface oiliness, promoting more balanced and less shiny skin.
Its use may contribute to improving the characteristic appearance of oily or seborrhoeic skin within properly planned professional protocols.
Clinical benefits
✔ Helps control excess oiliness.
✔ Promotes visibly more balanced skin.
✔ Contributes to reducing surface shine.
✔ Integrates into professional sebum-regulating programmes.
________________________________________
🫧 Progressive pore purification
What does it provide clinically?
The exfoliating action of Salicylic Acid promotes the removal of corneous residues, keratinous material and superficial impurities that may accumulate around the pilosebaceous follicle.
This action contributes to keeping pores cleaner, progressively reducing skin congestion and improving their visible appearance.
Clinical benefits
✔ Promotes pore cleansing.
✔ Helps remove accumulated impurities.
✔ Contributes to reducing superficial congestion.
✔ Promotes the visual refinement of enlarged pores.
________________________________________
⚪ Improvement in the appearance of comedones and imperfections
What does it provide clinically?
Higher-intensity superficial exfoliation promotes the removal of accumulated corneocytes involved in the obstruction of the pilosebaceous follicle.
Within properly indicated protocols, it may contribute to improving the appearance of comedones, blackheads and superficial imperfections characteristic of acne-prone skin.
Clinical benefits
✔ Helps improve the appearance of blackheads.
✔ Contributes to reducing superficial comedones.
✔ Promotes less congested skin.
✔ Supports professional protocols for acne-prone skin.
________________________________________
🎯 Refinement of skin texture
What does it provide clinically?
The progressive renewal of the most superficial layers of the epidermis helps to reorganise the skin microrelief and promotes a visibly smoother, more regular and more even texture.
With appropriate patient selection, it may contribute to improving the appearance of superficial irregularities and superficial post-acne scars.
Clinical benefits
✔ Helps improve superficial texture.
✔ Promotes smoother skin.
✔ Progressively reduces the sensation of roughness.
✔ May contribute to improving the appearance of superficial acne scars.
________________________________________
🌟 Improvement in the visual uniformity of skin tone
What does it provide clinically?
Photoageing, recurrent imperfections and certain inflammatory processes may leave visible skin tone irregularities.
Progressive epidermal renewal may contribute to improving the appearance of these superficial irregularities and promoting visibly more even skin.
Clinical benefits
✔ Promotes greater visual uniformity of skin tone.
✔ May contribute to improving the appearance of superficial post-inflammatory hyperpigmentation.
✔ Helps reduce the appearance of superficial freckles and lentigines.
✔ Promotes visibly more even skin.
________________________________________
☀️ Improvement in the appearance of superficial photodamage
What does it provide clinically?
Accumulated sun exposure may promote texture irregularities, visible tone alterations and a less even skin appearance.
Within properly indicated professional protocols, Salicylic Peel 25% may contribute to promoting superficial epidermal renewal and progressively improving the appearance of photodamage.
Clinical benefits
✔ Promotes renewal of the skin surface.
✔ Contributes to improving the appearance of irregularities associated with photodamage.
✔ Helps promote visibly more even skin.
✔ May be integrated into professional skin renewal programmes.
________________________________________
✨ Cleaner, renewed and more balanced appearance
What does it provide clinically?
The combination of superficial exfoliation, sebum regulation, pore purification and epidermal renewal progressively promotes skin that looks cleaner, more even, balanced and healthy.
Clinical benefits
✔ Promotes visibly cleaner skin.
✔ Contributes to a more even appearance.
✔ Helps improve the overall clarity of the skin.
✔ Promotes a more renewed and healthier appearance.
________________________________________
🛡️ Clinically controlled higher-intensity superficial exfoliation
What does it provide clinically?
The 25% concentration allows the development of higher-intensity superficial exfoliation protocols when there is an appropriate clinical indication.
Its use requires careful patient selection, an accurate assessment of the skin barrier and individual adaptation of contact time, application technique and treatment frequency.
Clinical benefits
✔ Allows the development of higher-intensity superficial protocols.
✔ Promotes clinically controlled exfoliation.
✔ Expands the therapeutic possibilities of Salicylic Acid.
✔ Facilitates the adaptation of treatment to more specific clinical objectives.
________________________________________
📈 Progressive clinical evolution
The benefits associated with Salicylic Peel 25% form part of a progressive biological process and do not depend on a single session.
The clinical response develops as applications progress, while respecting recovery of the skin barrier, individual tolerance and the evolution of the skin.
An accurate diagnosis, appropriate patient selection and personalised therapeutic planning make it possible to develop protocols consistent with the established clinical objectives.
________________________________________
CLINICAL SUMMARY
Main benefits of Salicylic Peel 25%
✔ Progressive regulation of excess sebum.
✔ Purification and visual refinement of pores.
✔ Improvement in the appearance of comedones and imperfections.
✔ Refinement of skin texture.
✔ Improvement in the appearance of superficial acne scars.
✔ Improvement in the visual uniformity of skin tone.
✔ Support for protocols targeting superficial post-inflammatory hyperpigmentation.
✔ Progressive improvement in the appearance of photodamage.
✔ Cleaner, renewed and more balanced appearance.
✔ Clinically controlled higher-intensity superficial exfoliation.
✔ Progressive clinical evolution.
________________________________________
THERAPDERMA CLINICAL CONCLUSION
The main clinical value of Salicylic Peel 25% lies in combining higher-intensity superficial exfoliation with a purifying, keratolytic and sebum-regulating action, especially indicated for appropriately selected patients.
Integrated into the TherapDerma Clinical Ecosystem™, it may form part of therapeutic strategies based on diagnosis, clinical planning and periodic reassessment, allowing the development of personalised protocols for oily skin, acne-prone skin, enlarged pores, uneven texture, photodamage and superficial pigmentation irregularities.
Its objective is not to perform aggressive exfoliation, but to promote carefully controlled superficial renewal that contributes to achieving skin that is less oily, cleaner, more even and visibly renewed.

Why choose salicylic peel 25%?

A professional option for higher-intensity superficial exfoliation protocols, sebum regulation, epidermal renewal and progressive improvement in the appearance of the skin
In professional aesthetic medicine, the choice of a chemical peel should not be based solely on the acid concentration, but on selecting the active ingredient and level of action most appropriate for the biological characteristics and specific needs of each patient.
Salicylic Peel 25% TherapDerma has been developed for professionals wishing to incorporate a Beta Hydroxy Acid (BHA) intended for higher-intensity superficial exfoliation protocols in oily, seborrhoeic, congested, acne-prone, photoaged skin or skin with superficial pigmentation irregularities.
Its main distinguishing characteristic is the lipophilic nature of Salicylic Acid, which promotes selective action on areas with a higher sebaceous content, making it an especially suitable tool when the clinical objective is to control excess oiliness, purify the pilosebaceous environment and progressively improve the appearance of pores, texture and superficial imperfections.
More than representing a higher concentration, Salicylic Peel 25% is a clinical tool designed to be integrated into personalised protocols requiring a more intensive superficial action that is carefully controlled and respectful of skin physiology.
________________________________________
WHEN MAY IT BE A SUITABLE OPTION?
Salicylic Peel 25% may be considered when the main objective of treatment is to promote higher-intensity superficial exfoliation with keratolytic, purifying, sebum-regulating and renewing action.
It may be considered particularly in protocols intended for:
✔ oily or seborrhoeic skin;
✔ acne-prone skin;
✔ appropriately selected acne vulgaris;
✔ excess oiliness;
✔ open and closed comedones;
✔ blackheads;
✔ enlarged or clogged pores;
✔ congested skin;
✔ uneven superficial texture;
✔ superficial post-acne scars;
✔ superficial post-inflammatory hyperpigmentation;
✔ superficial freckles and lentigines;
✔ visible signs of photodamage;
✔ appropriately selected seborrhoeic dermatitis;
✔ moderate actinic keratosis where there is a professional indication within the applicable scope of practice;
✔ professional skin renewal and purification programmes.
The indication should always be established following an individualised professional assessment.
________________________________________
WHAT TYPE OF PROFESSIONAL HAS IT BEEN DESIGNED FOR?
Salicylic Peel 25% is intended for professionals who understand that the use of a higher concentration requires an accurate diagnosis, rigorous patient selection and individualised therapeutic planning.
It is particularly useful for clinics wishing to develop protocols aimed at controlling oily and acne-prone skin, as well as progressively improving superficial irregularities in texture, tone and photodamage.
Its use requires the correct interpretation of the skin response and adaptation of the frequency, exposure time, number of layers, treatment area and progression of the protocol according to each patient’s biological characteristics.
________________________________________
THERAPDERMA CLINICAL LADDER™
Each peel addresses a different clinical need
The TherapDerma Clinical Ladder™ does not represent a mandatory progression between concentrations.
Each solution should be selected according to:
✔ professional diagnosis;
✔ clinical objective;
✔ physiological condition of the skin;
✔ integrity of the skin barrier;
✔ level of oiliness;
✔ presence of inflammation;
✔ phototype;
✔ anticipated tolerance;
✔ therapeutic strategy;
✔ observed clinical progression.
Within the BHA collection, Salicylic Peel 25% occupies a position intended for higher-intensity superficial exfoliation protocols aimed at controlling oiliness, promoting epidermal renewal and progressively improving visible irregularities in skin texture and tone.
________________________________________
SALICYLIC PEEL 25%
It may be considered for:
✔ oily or seborrhoeic skin;
✔ excess oiliness;
✔ acne-prone skin;
✔ appropriately selected acne vulgaris;
✔ blackheads and comedones;
✔ enlarged or clogged pores;
✔ congested skin;
✔ uneven texture;
✔ superficial post-acne scars;
✔ superficial post-inflammatory hyperpigmentation;
✔ superficial freckles and lentigines;
✔ signs of photodamage;
✔ appropriately selected seborrhoeic dermatitis;
✔ moderate actinic keratosis where there is a professional indication;
✔ intensive superficial renewal programmes.
Each protocol should always be adapted to the professional diagnosis and the individual biological response.
________________________________________
QUICK SELECTION GUIDE
Clinical objective Option that may be considered
Control of excess sebum Salicylic Peel 25%
Oily or seborrhoeic skin Salicylic Peel 25%
Acne-prone skin Salicylic Peel 25%
Appropriately selected acne vulgaris Salicylic Peel 25%
Comedones and blackheads Salicylic Peel 25%
Enlarged or clogged pores Salicylic Peel 25%
Congested skin Salicylic Peel 25%
Purification of the pilosebaceous environment Salicylic Peel 25%
Texture refinement Salicylic Peel 25%
Superficial acne scars Salicylic Peel 25%
Superficial post-inflammatory hyperpigmentation Salicylic Peel 25%
Superficial freckles and lentigines Salicylic Peel 25%
Superficial photodamage Salicylic Peel 25%
Appropriately selected seborrhoeic dermatitis Salicylic Peel 25%
Higher-intensity superficial exfoliation Salicylic Peel 25%
This guide provides general guidance and does not replace an individualised professional assessment.
________________________________________
WHY INTEGRATE IT INTO A PROGRESSIVE PROGRAMME?
The improvement of oily, acne-prone, photoaged skin or skin with superficial tone irregularities does not depend on a single session.
The progression of the skin’s appearance requires progressive protocols that respect physiological skin recovery and allow the individual response to be assessed after each application.
Within this approach, Salicylic Peel 25% may be incorporated into professional programmes intended to control oiliness, purify pores, progressively improve texture and promote greater visual uniformity of skin tone.
Due to its higher concentration, each new application should be established only after confirming adequate recovery of the skin barrier, individual tolerance and the absence of skin reactions incompatible with continuation of the protocol.
Where there is a clinical indication, it may subsequently be integrated with other procedures from the TherapDerma Clinical Ecosystem™, while always respecting the therapeutic sequence, physiological recovery intervals and the established treatment plan.
________________________________________
THERAPDERMA CLINICAL CONCLUSION
Salicylic Peel 25% is a professional tool especially indicated for higher-intensity superficial exfoliation protocols aimed at the cosmetic control of oily skin, pore purification and the progressive improvement of visible texture and tone irregularities.
Its affinity for the sebum-rich environment makes it possible to develop therapeutic strategies adapted to acne-prone skin, enlarged pores, superficial post-acne scars, photodamage and superficial hyperpigmentation, provided that appropriate patient selection has been carried out.
Within the TherapDerma Clinical Ladder™, it represents a solution intended for professionals who prioritise diagnosis, treatment individualisation, intensity control and respect for skin physiology as the basis for achieving progressive, safe and sustainable results.

Areas Of Application

One peel. Different clinical possibilities according to the anatomical area, therapeutic objective and professional diagnosis.
Salicylic Peel 25% TherapDerma may be incorporated into different higher-intensity superficial exfoliation protocols intended for oil control, purification of the pilosebaceous environment, epidermal renewal and the progressive improvement of visible texture and tone irregularities.
Thanks to the lipophilic nature of Salicylic Acid, this formulation has a particular affinity for areas with greater sebaceous activity, allowing the development of protocols adapted to different anatomical regions whenever there is a professional indication and appropriate patient selection.
Each area differs in terms of epidermal thickness, density of sebaceous glands, level of photodamage, sensitivity and recovery capacity. For this reason, the amount applied, contact time, number of layers, treatment area and frequency should be carefully individualised.
________________________________________
FACE
The main area of application
The face is the main area of application for Salicylic Peel 25%.
It may be incorporated into professional protocols intended for appropriately selected patients presenting oily skin, excess oiliness, enlarged or clogged pores, comedones, acne-prone skin, uneven texture, superficial post-inflammatory hyperpigmentation, freckles, lentigines or visible signs of photodamage.
Common objectives:
✔ promote oil control;
✔ purify the pilosebaceous environment;
✔ improve the appearance of pores and comedones;
✔ promote a visibly more even texture;
✔ improve the appearance of superficial post-acne marks;
✔ promote greater visual uniformity of skin tone;
✔ support professional protocols for superficial photodamage.
Application should always be adapted to the different facial regions, avoiding particularly sensitive areas and respecting the skin response observed during the procedure.
________________________________________
NECK
Localised application in carefully selected cases
The neck generally has lower sebaceous activity, a more delicate epidermis and greater sensitivity than certain areas of the face.
For this reason, Salicylic Peel 25% should only be applied locally when there is a specific professional indication, the skin barrier is intact and the professional considers that the area is suitable for higher-intensity superficial exfoliation.
The amount of product, contact time and treatment area should be reduced and carefully adapted.
________________________________________
DÉCOLLETAGE
Photodamage and superficial irregularities in selected patients
The décolletage is an area frequently exposed to solar radiation and may present visible tone irregularities, lentigines, uneven texture or superficial signs of photodamage.
In appropriately selected patients, Salicylic Peel 25% may be incorporated into localised protocols intended to promote epidermal renewal and progressively improve the appearance of these irregularities.
Due to the sensitivity and recovery capacity of this area, the treatment area, contact time and frequency should be individualised with particular caution.
________________________________________
BACK
One of the main body indications
The back is one of the body areas with the greatest sebaceous activity and a frequent site of comedones, clogged pores, body acne and residual marks following imperfections.
Salicylic Peel 25% may be incorporated into professional protocols intended to:
✔ control excess oiliness;
✔ purify clogged follicles;
✔ improve the appearance of comedones and blackheads;
✔ promote visibly less congested skin;
✔ progressively improve skin texture;
✔ contribute to improving the appearance of superficial acne scars;
✔ promote greater visual uniformity of skin tone.
The amount of product, treatment area and contact time should be adapted to the size of the area and individual tolerance.
________________________________________
CHEST
Localised protocols for oily skin, body acne and photodamage
Certain areas of the chest may present excess oiliness, comedones, superficial imperfections, post-inflammatory marks or visible signs of photodamage.
Where there is a professional indication, Salicylic Peel 25% may form part of localised protocols intended to purify the pilosebaceous environment, promote superficial renewal and progressively improve the appearance of texture and tone.
Application should avoid particularly sensitive areas and be carefully adapted to the skin response.
________________________________________
BEARD AND MALE AREA
Carefully selected intensive protocols
Male skin generally presents greater sebaceous activity, a thicker stratum corneum and a higher incidence of clogged pores, ingrown hairs and shaving-related pseudofolliculitis.
In appropriately selected patients, Salicylic Peel 25% may be incorporated into protocols intended to:
✔ control excess oiliness;
✔ promote purification of the pilosebaceous follicle;
✔ improve the appearance of ingrown hairs;
✔ reduce shaving-related congestion;
✔ promote a visibly more even texture.
Application should not be performed immediately after shaving, and the frequency should be adapted to the patient’s shaving habits, the condition of the skin barrier and the individual clinical response.
________________________________________
SHOULDERS
Body protocols for acne, pores and uneven texture
The shoulders are another frequent site of body acne, excess oiliness, clogged pores and post-inflammatory marks.
In appropriately selected patients, Salicylic Peel 25% may be incorporated into protocols intended to purify the area, improve the appearance of imperfections and promote a visibly more even texture and tone.
________________________________________
AREAS WITH SUPERFICIAL PIGMENTATION IRREGULARITIES
Localised application under professional diagnosis
Salicylic Peel 25% may be considered for certain areas presenting superficial post-inflammatory hyperpigmentation, freckles, lentigines or visible signs of photodamage.
The indication should be established after correctly differentiating the type, depth and origin of the pigmentation irregularity.
Not all pigmentation responds to the same treatment, and any pigmented lesion of uncertain diagnosis should be medically assessed before the procedure is performed.
________________________________________
MODERATE ACTINIC KERATOSIS
Application exclusively within the corresponding professional and legal framework
The manufacturer’s documentation includes moderate actinic keratosis among the possible indications for Salicylic Peel 25%.
As this is a lesion associated with chronic sun damage and of potential medical relevance, its assessment, diagnosis and treatment should be performed exclusively by legally authorised healthcare professionals and within the applicable regulatory framework.
Salicylic Peel 25% should not be applied to any suspicious or undiagnosed lesion, or to any lesion presenting recent changes in shape, size, colour, surface or symptoms.
________________________________________
CLINICAL GUIDANCE ACCORDING TO THE AREA
Anatomical Area Main objective
Face Oiliness, pores, comedones, texture, photodamage and uneven tone
Neck Localised application in carefully selected cases
Décolletage Photodamage, lentigines and uneven texture
Back Body acne, excess sebum and superficial marks
Chest Oiliness, localised acne, photodamage and superficial tone irregularities
Beard Male skin, ingrown hairs and pseudofolliculitis
Shoulders Body acne, clogged pores and uneven texture
Pigmented areas Post-inflammatory hyperpigmentation, freckles and superficial lentigines
________________________________________
MULTI-AREA PROTOCOLS
In certain patients, Salicylic Peel 25% may be incorporated into therapeutic programmes involving the sequential treatment of different anatomical areas.
Due to its higher concentration, it is not always advisable to treat extensive surfaces or multiple areas during the same session.
The selection and sequencing of areas should always be based on professional diagnosis and the individual assessment of:
• sebaceous activity;
• the presence and type of imperfections;
• the degree of photodamage;
• the type and apparent depth of pigmentation irregularities;
• the total area intended for treatment;
• the integrity of the skin barrier;
• skin sensitivity;
• recovery capacity;
• phototype;
• individual tolerance.
Planning should respect the physiological intervals between procedures and be adapted to the clinical progression observed after each session.
________________________________________
CLINICAL CONSIDERATIONS
Before each procedure, the professional should assess:
✔ the physiological condition of the skin;
✔ sebaceous activity;
✔ the degree of inflammation;
✔ skin sensitivity;
✔ the integrity of the skin barrier;
✔ phototype;
✔ the degree of recent sun exposure;
✔ the presence of post-inflammatory hyperpigmentation;
✔ the characteristics of any pigmented lesion;
✔ recent cosmetic or medical treatments;
✔ relevant medical history;
✔ possible allergy to Salicylic Acid, aspirin or other salicylates.
The application technique should be individualised according to the treatment area, extent, clinical objective and observed biological response.
________________________________________
QUICK SUMMARY
Salicylic Peel 25% may be incorporated into professional protocols intended for:
✔ face;
✔ neck in carefully selected cases;
✔ décolletage;
✔ back;
✔ chest;
✔ shoulders;
✔ beard and male area;
✔ localised areas with photodamage or correctly diagnosed superficial pigmentation irregularities.
Main objectives
✔ control of excess oiliness;
✔ purification of the pilosebaceous environment;
✔ improvement in the appearance of comedones;
✔ support for acne-prone skin;
✔ improvement in the appearance of enlarged pores;
✔ progressive refinement of skin texture;
✔ improvement of superficial post-acne scars;
✔ visual improvement of superficial post-inflammatory hyperpigmentation;
✔ support for protocols targeting freckles, lentigines and superficial photodamage.
________________________________________
THERAPDERMA CONCLUSION
Salicylic Peel 25% is a versatile professional solution for higher-intensity superficial exfoliation protocols intended for oily, acne-prone, photoaged skin or skin with superficial texture and tone irregularities, both facially and on the body.
Its application should be rigorously adapted to the specific characteristics of each anatomical area and always performed within an individualised clinical treatment plan, with careful patient selection and precise control of the treatment area, technique and contact time.
Integrated into an appropriate professional strategy, it allows the development of progressive treatments aimed at oil control, epidermal renewal and visible improvement in skin quality.

How Does It Work?

Understanding the biological process makes it possible to plan higher-intensity superficial exfoliation protocols with greater precision.
Although the application of Salicylic Peel 25% TherapDerma is carried out over a limited period of time, the skin’s biological response continues to evolve during the days following the procedure.
Each session initiates a carefully controlled process of superficial exfoliation that promotes the physiological renewal of the epidermis, helps purify the pilosebaceous environment and contributes to progressively improving the appearance of oily, acne-prone, photoaged skin or skin with superficial tone irregularities.
Understanding these phases allows the professional to correctly interpret clinical progression, establish personalised protocols and adapt each session to the patient’s individual biological response.
________________________________________
EVERYTHING BEGINS AT THE SURFACE OF THE SKIN
The peel first interacts with the stratum corneum, particularly in areas with greater sebaceous activity or an accumulation of superficial corneocytes.
Over time, hyperkeratinisation, excess sebum, progressive obstruction of the pilosebaceous follicle and sun exposure may contribute to congested-looking skin, more visible pores, uneven texture and superficial tone irregularities.
The application of Salicylic Peel 25% initiates a higher-intensity, carefully controlled superficial chemical exfoliation that promotes the progressive removal of these accumulations, while always respecting the skin barrier when the procedure is performed under professional supervision.
________________________________________
STEP 1
Carefully controlled superficial exfoliation
During the first few minutes following application, Salicylic Acid begins to act on the most superficial layers of the epidermis.
This process promotes the progressive removal of accumulated corneocytes and prepares the skin for its physiological renewal process.
The clinical response will depend on multiple factors, including:
✔ the formulation;
✔ the pH;
✔ the concentration;
✔ the amount applied;
✔ the contact time;
✔ the professional technique;
✔ the physiological condition of the skin;
✔ the integrity of the skin barrier;
✔ individual sensitivity.
________________________________________
STEP 2
Progressive renewal of the epidermis
Once exfoliation has begun, the epidermis continues its physiological renewal process.
The progressive reorganisation of the stratum corneum promotes a visibly more even skin surface and facilitates the gradual improvement of texture, pore appearance and certain superficial tone irregularities.
This process forms part of normal biological progression and requires respect for the physiological recovery periods between sessions.
________________________________________
STEP 3
Progressive purification of the pilosebaceous environment
Thanks to the lipophilic nature of Salicylic Acid, superficial exfoliation progressively promotes more effective cleansing of the sebum-rich environment.
As treatment progresses, the skin may appear visibly less congested, with a progressive improvement in the appearance of pores, comedones and other superficial imperfections.
Results will always depend on the diagnosis, the biological characteristics of the skin and correct therapeutic planning.
________________________________________
STEP 4
Progressive improvement in the appearance of the skin
As the epidermis completes its renewal process, the skin may progressively present:
✔ a less oily appearance;
✔ a more even texture;
✔ visibly less noticeable pores;
✔ cleaner-looking skin;
✔ greater visual uniformity of skin tone;
✔ a progressive improvement in the appearance of superficial post-acne marks;
✔ a progressive improvement in the appearance of superficial photodamage;
✔ progressive optimisation of Skin Quality.
These changes develop gradually and should always be assessed while respecting the individual biological response.
________________________________________
STEP 5
Clinical progression and professional reassessment
Each session represents one stage within a progressive treatment.
Continuation of the protocol should always be determined after assessing:
✔ the observed clinical response;
✔ recovery of the skin barrier;
✔ individual tolerance;
✔ the progression of oiliness;
✔ the appearance of the pores;
✔ the progression of superficial imperfections;
✔ the progression of skin texture;
✔ the progression of superficial tone irregularities;
✔ compliance with home care;
✔ the defined therapeutic objectives.
Treatment planning should never be based solely on a fixed schedule, but on the individual clinical progression of each patient.
________________________________________
WHY IS IT IMPORTANT TO MAINTAIN A PROGRESSIVE APPROACH?
Improving oily, acne-prone, photoaged skin or skin with superficial tone irregularities is a cumulative process.
The objective is not to perform increasingly aggressive procedures, but to promote carefully controlled epidermal renewal that is compatible with the physiological recovery of the skin.
Progressive planning makes it possible to adapt each session to clinical progression and maintain a high safety profile, even when working with a higher concentration of Salicylic Acid.
________________________________________
A DIFFERENT RESPONSE IN EACH PATIENT
Each skin responds differently to a chemical peel.
Clinical progression will depend on factors such as:
✔ the degree of oiliness;
✔ sebaceous activity;
✔ the condition of the skin barrier;
✔ skin sensitivity;
✔ phototype;
✔ age;
✔ the degree of photoageing;
✔ the presence of superficial hyperpigmentation;
✔ previous treatments;
✔ adherence to home care;
✔ the individual biological response.
For this reason, two patients undergoing the same protocol may present different recovery times and results.
________________________________________
SEQUENCE OF THE BIOLOGICAL PROCESS
Professional application

Carefully controlled superficial exfoliation

Progressive renewal of the stratum corneum

Purification of the pilosebaceous environment

Progressive improvement in texture and pore appearance

Greater visual uniformity of skin tone

Progressive optimisation of Skin Quality
________________________________________
KEYS TO HOW IT WORKS
✔ carefully controlled higher-intensity superficial exfoliation;
✔ physiological renewal of the epidermis;
✔ preferential action on areas with a higher sebaceous content;
✔ progressive purification of the pilosebaceous environment;
✔ gradual improvement in pore appearance;
✔ progressive refinement of skin texture;
✔ progressive improvement in the appearance of skin tone;
✔ progressive optimisation of Skin Quality;
✔ personalised, progressive and cumulative protocols.
________________________________________
THERAPDERMA CONCLUSION
Understanding how Salicylic Peel 25% works makes it possible to correctly interpret clinical progression and plan protocols adapted to the specific needs of each patient.
Its action promotes higher-intensity, carefully controlled superficial exfoliation that contributes to progressively improving the appearance of oily, acne-prone, photoaged skin or skin with superficial tone irregularities through physiological renewal that respects the skin barrier.
When treatment is integrated into an individualised professional plan, each session represents a further step towards skin that appears visibly cleaner, more even, renewed and balanced.

Mechanism Of Action

The science that explains the biological response of Salicylic Acid
The mechanism of action of Salicylic Peel 25% TherapDerma is based on the interaction between Salicylic Acid, the formulation, the pH and the individual biological characteristics of the skin.
From a scientific perspective, the objective of the procedure is to promote higher-intensity, carefully controlled superficial exfoliation, help progressively regulate excess sebum and promote epidermal renewal compatible with professional protocols intended for the cosmetic treatment of oily, acne-prone, photoaged skin or skin with superficial tone irregularities.
The clinical response will always depend on the diagnosis, the physiological condition of the epidermis, sebaceous activity, phototype, the individual characteristics of the patient and the correct application of the professional protocol.
________________________________________
ACTION ON THE STRATUM CORNEUM AND THE PILOSEBACEOUS ENVIRONMENT
The stratum corneum constitutes the skin’s first protective barrier and represents one of the main levels of action of Salicylic Peel 25%.
At the same time, the lipophilic nature of Salicylic Acid promotes preferential action on the sebum-rich environment, where corneocytes, impurities, keratinous material and lipid residues may accumulate.
Where there is an appropriate professional indication, the peel promotes higher-intensity superficial exfoliation and reorganisation of the skin microrelief through the characteristic mechanisms of Beta Hydroxy Acids (BHAs).
________________________________________
MODULATION OF COHESION BETWEEN CORNEOCYTES
Superficial corneocytes remain connected by specialised structures known as corneodesmosomes.
Salicylic Acid promotes a progressive reduction in cohesion between these cellular junctions, facilitating the physiological removal of corneocytes that have completed their biological cycle.
As a result of this process, the skin surface may progressively present:
• a more even texture;
• visibly cleaner skin;
• reduced superficial accumulation of impurities;
• a more homogeneous appearance;
• progressive improvement in certain superficial tone irregularities;
• improved visual skin quality.
The intensity of this response will always depend on the individual characteristics of the skin and the selected protocol.
________________________________________
ACTION ON THE SEBUM-RICH ENVIRONMENT
One of the main characteristics of Salicylic Acid is its affinity for lipids.
This property promotes preferential action on areas with greater sebaceous activity, helping to maintain the pilosebaceous environment in better condition and promoting visibly more balanced skin.
Within properly planned protocols, it may contribute to:
✔ promoting the balance of oily skin;
✔ helping to keep pores cleaner;
✔ reducing the superficial accumulation of impurities;
✔ progressively improving the appearance of comedones;
✔ promoting less congested skin;
✔ contributing to the progressive refinement of skin texture.
________________________________________
EPIDERMAL RENEWAL AND SUPERFICIAL REORGANISATION
Epidermal renewal is a continuous physiological process through which the epidermis progressively replaces its superficial cells.
When this process occurs less efficiently, particularly in skin with high sebaceous activity or affected by photoageing, texture irregularities, visible tone alterations and a less even skin appearance may develop.
By promoting carefully controlled superficial exfoliation, Salicylic Peel 25% helps this renewal take place in a more organised manner, promoting progressively more even, renewed and balanced skin.
________________________________________
RELATIONSHIP BETWEEN CONCENTRATION, pH AND SKIN RESPONSE
Concentration represents only one of the factors that determine the clinical behaviour of a chemical peel.
The biological response also depends on variables such as:
✔ the pH of the formulation;
✔ the available acid fraction;
✔ the vehicle used;
✔ the contact time;
✔ the application technique;
✔ the number of layers;
✔ prior skin preparation;
✔ sebaceous activity;
✔ the condition of the skin barrier;
✔ phototype;
✔ individual sensitivity.
For this reason, two formulations with the same concentration may produce different clinical responses.
The professional assessment should always consider all of these variables before establishing the protocol.
________________________________________
INTEGRATION INTO THERAPEUTIC PROTOCOLS
Salicylic Peel 25% may be incorporated into sequential therapeutic strategies where the diagnosis indicates this.
Once the skin barrier has recovered, the professional may consider integrating it with other procedures from the TherapDerma Clinical Ecosystem™, such as:
• mesotherapy;
• depigmenting protocols;
• sebum-regulating protocols;
• LED therapy;
• biostimulation;
• PDRN;
• medical-aesthetic technologies;
• personalised Skin Quality programmes;
• maintenance protocols.
The combination of procedures should always be individualised according to the clinical progression of each patient.
________________________________________
SCIENCE AT A GLANCE™
Parameter | Salicylic Peel 25%
Active ingredient | Salicylic Acid
Chemical family | Beta Hydroxy Acids (BHA)
Main level of action | Stratum corneum and pilosebaceous environment
Predominant mechanism | Carefully controlled higher-intensity superficial exfoliation
Associated physiological process | Progressive epidermal renewal
Expected physiological result | Visibly cleaner, more even, renewed and balanced skin
Determining variables | pH, formulation, concentration, technique, contact time and individual characteristics
Clinical purpose | To support professional protocols for oily skin, acne-prone skin, photodamage and superficial tone irregularities
________________________________________
BIOLOGICAL BASIS
The clinical behaviour of a chemical peel depends on the biological response developed by the skin following application of the active ingredient and not exclusively on its concentration.
In the case of Salicylic Acid, its affinity for the sebum-rich environment promotes selective superficial action that contributes to progressively improving the appearance of oily, acne-prone skin and certain superficial texture and tone irregularities.
The progression of treatment will always depend on professional diagnosis, the functional condition of the skin and the individual biological response.
________________________________________
SCIENTIFIC PRINCIPLES OF USE
The interpretation of the mechanism of action should be based on several fundamental principles:
✔ the biological response is always individual;
✔ concentration alone does not determine clinical behaviour;
✔ the skin barrier determines tolerance;
✔ sebaceous activity influences clinical progression;
✔ phototype influences therapeutic planning;
✔ pH and formulation modify the availability of the active ingredient;
✔ protocol planning is more important than the isolated intensity of a single session;
✔ clinical reassessment makes it possible to adapt treatment to each patient;
✔ the result depends on the diagnosis, indication and correct execution of the procedure.
________________________________________
THERAPDERMA CONCLUSION
Understanding the mechanism of action of Salicylic Peel 25% makes it possible to interpret the biological response of the skin from a scientific perspective and plan more precise professional protocols.
Its efficacy is based on the interaction between the formulation, pH, concentration, application technique and the biological characteristics of each patient, promoting carefully controlled superficial exfoliation and progressive improvement in the appearance of oily, acne-prone, photoaged skin or skin with superficial tone irregularities.
Integrated into the TherapDerma Clinical Ecosystem™, it constitutes a tool intended to develop personalised protocols that respect skin physiology, the patient’s individual progression and the principles of professional aesthetic practice based on clinical diagnosis.

Scientific Foundations

The formulation determines clinical behaviour
In a professional chemical peel, the acid concentration represents only one of the many factors involved in the skin’s biological response.
The clinical behaviour of a formulation depends on the interaction between its physicochemical properties, the functional availability of the active ingredient, the application technique and the individual biological characteristics of each patient.
For this reason, apparently similar formulations may produce different clinical responses, even when they contain the same nominal concentration of Salicylic Acid.
Salicylic Peel 25% TherapDerma has been developed to be integrated into professional protocols in which the complete formulation constitutes an essential element for achieving a predictable, reproducible clinical response consistent with the physiology of oily, acne-prone, photoaged skin or skin with superficial texture and tone irregularities.
________________________________________
CONCENTRATION
An important factor, but never sufficient on its own
Concentration expresses the nominal amount of Salicylic Acid present in the formulation, but by itself it does not determine the intensity or the clinical behaviour of the procedure.
Two peels with the same concentration may behave differently due to variations in:
• pH;
• vehicle;
• formulation stability;
• available acid fraction;
• contact time;
• application technique;
• sebaceous activity;
• skin barrier condition;
• the physiological condition of the skin.
In Salicylic Peel 25%, the concentration of the active ingredient has been selected to support higher-intensity superficial exfoliation protocols aimed at controlling excess oil, purifying the pilosebaceous environment, promoting epidermal renewal and progressively improving superficial texture and tone irregularities.
________________________________________
THE ROLE OF pH
A regulator of formulation behaviour
pH is one of the most important physicochemical parameters in the design of a professional chemical peel.
In addition to expressing the acidity of the formulation, it influences the functional availability of Salicylic Acid and determines its behaviour during the procedure.
Small variations in pH may modify the clinical response of formulations with a similar concentration.
For this reason, pH is one of the elements that contributes to the safety, reproducibility and predictability of treatment.
________________________________________
THE SIGNIFICANCE OF pKa
Understanding the chemical balance of Salicylic Acid
pKa is an intrinsic physicochemical property of every acid that describes the equilibrium between its ionised and non-ionised forms.
Salicylic Acid has an approximate pKa of 2.97, a value that helps explain its chemical behaviour in different formulations.
This parameter is useful for interpreting the functional availability of the active ingredient, although it does not by itself predict the clinical response obtained.
Its interpretation should always be considered together with the pH, concentration, formulation and the patient’s biological characteristics.
________________________________________
PHYSICOCHEMICAL PROFILE OF SALICYLIC ACID
Scientific characteristics of the active ingredient
Salicylic Acid belongs to the Beta Hydroxy Acid (BHA) family.
Its lipophilic nature provides a high affinity for skin lipids and the pilosebaceous environment, a characteristic that differentiates it from Alpha Hydroxy Acids (AHAs).
These properties promote selective superficial exfoliation and make it possible to develop professional protocols specifically intended for the cosmetic treatment of oily or acne-prone skin.
In correctly formulated higher concentrations, it may also be integrated into protocols intended to promote epidermal renewal and progressively improve the appearance of photodamage, superficial tone irregularities and superficial post-acne scars.
________________________________________
SCIENTIFIC MOLECULAR PROFILE™
Parameter Salicylic Acid
Chemical name Salicylic Acid
Chemical family Beta Hydroxy Acid (BHA)
Molecular formula C₇H₆O₃
Molecular weight 138.12 g/mol
Chemical nature Lipophilic aromatic acid
pKa ≈ 2.97
Predominant affinity Lipid and pilosebaceous environment
Main level of action Stratum corneum and pilosebaceous environment
Type of exfoliation Selective superficial chemical exfoliation
The clinical relevance of these characteristics lies in the interaction between the active ingredient, the complete formulation and skin biology.
________________________________________
WHY CAN TWO PEELS BEHAVE DIFFERENTLY?
Much more than concentration
Although two peels may share the same active ingredient and an apparently similar concentration, their clinical behaviour may be different.
The biological response depends on the interaction between:
✔ Salicylic Acid concentration;
✔ pH;
✔ pKa;
✔ available acid fraction;
✔ vehicle and excipients;
✔ formulation stability;
✔ application technique;
✔ number of layers;
✔ amount applied;
✔ contact time;
✔ sebaceous activity;
✔ skin barrier condition;
✔ phototype;
✔ individual biological response.
The scientific interpretation of a chemical peel should always take all of these factors into consideration.
________________________________________
THE VEHICLE AND THE FORMULATION
The invisible architecture of the peel
In addition to the active ingredient, every formulation contains a vehicle and different excipients that determine product stability and its distribution across the skin surface.
These components influence application uniformity, the functional availability of Salicylic Acid and the clinical reproducibility of the procedure.
A properly developed formulation supports more homogeneous, consistent and clinically controllable protocols.
________________________________________
CONTACT TIME
A variable that must be individualised
The length of time that the peel remains on the skin is one of the most important clinical variables.
For Salicylic Peel 25%, its duration should be established with particular precision according to:
• the diagnosis;
• the therapeutic objective;
• the treatment area;
• sebaceous activity;
• stratum corneum thickness;
• phototype;
• skin barrier integrity;
• observed tolerance;
• clinical progression during the session.
There is no universal contact time suitable for every patient.
The use of a higher concentration does not justify automatically extending the contact time or increasing the number of layers.
________________________________________
THE SKIN BARRIER
The foundation of an appropriate physiological response
The integrity of the skin barrier is one of the main factors determining tolerance to any chemical peel.
Factors such as hydration, sebaceous activity, previous treatments, recent sun exposure or certain dermatological conditions may modify the clinical response to the procedure.
For this reason, an initial assessment of the skin barrier is an essential step before beginning any protocol with Salicylic Peel 25%.
Treatment should only continue after confirming appropriate physiological recovery.
________________________________________
BIOLOGICAL VARIABILITY
Every skin responds differently
The biological response is never identical between two patients.
Age, phototype, sebaceous activity, stratum corneum thickness, skin sensitivity, inflammation, degree of photoageing, predisposition to post-inflammatory hyperpigmentation and previous therapeutic history may modify the clinical progression of treatment.
For this reason, every procedure should be adapted according to the observed progression through continuous reassessment.
________________________________________
FACTORS THAT MODIFY THE CLINICAL RESPONSE
An integrated view of the procedure
FORMULATION
✔ Concentration.
✔ pH.
✔ pKa.
✔ Available acid fraction.
✔ Vehicle.
✔ Stability.

PROCEDURE
✔ Skin preparation.
✔ Application technique.
✔ Amount applied.
✔ Number of layers.
✔ Contact time.
✔ Neutralisation according to the protocol.

PATIENT
✔ Skin barrier function.
✔ Sebaceous activity.
✔ Phototype.
✔ Individual sensitivity.
✔ Degree of photodamage.
✔ Predisposition to post-inflammatory hyperpigmentation.
✔ Diagnosis.

BIOLOGICAL RESPONSE

CLINICAL OUTCOME
________________________________________
SCIENCE AT A GLANCE™
Parameter Salicylic Peel 25%
Active ingredient Salicylic Acid
Concentration 25%
Main level of action Stratum corneum and pilosebaceous environment
Type of exfoliation Higher-intensity selective superficial chemical exfoliation
Predominant mechanism Superficial exfoliation and affinity for the sebum-rich environment
Expected outcome Progressive optimisation of texture, tone and Skin Quality
Determining variables Formulation, pH, concentration, technique, contact time and biological response
Clinical purpose Professional protocols for oily skin, acne-prone skin, photodamage and superficial texture and tone irregularities
________________________________________
SCIENTIFIC FORMULATION PROFILE™
Parameter Salicylic Peel 25%
Active ingredient Salicylic Acid
Concentration 25%
Chemical family Beta Hydroxy Acid (BHA)
Molecular formula C₇H₆O₃
Molecular weight 138.12 g/mol
Chemical nature Lipophilic aromatic acid
pKa ≈ 2.97
Professional presentation 50 mL
Intended use Professional use only
________________________________________
NEUTRALISATION
Restoring physiological balance
Neutralisation is an essential stage of the Salicylic Peel 25% procedure in accordance with the official technical protocol.
Its purpose is to stop the activity of the formulation in a controlled manner and initiate the physiological recovery of the skin surface.
The timing of neutralisation should be determined according to the professional protocol, the planned contact time and the clinical response observed during application.
________________________________________
APPLICATION OF SCIENTIFIC KNOWLEDGE
From the laboratory to clinical practice
Understanding the physicochemical properties of a formulation makes it possible to better interpret its behaviour during the clinical procedure.
Integrating this information with patient assessment facilitates selection of the most appropriate protocol, precise control of treatment intensity and progressive adaptation of the procedure.
________________________________________
SCIENTIFIC NOTE
Physicochemical properties help explain the potential behaviour of a formulation, but they never replace the clinical assessment performed by the professional.
Treatment progression will always depend on the interaction between the formulation, the application technique, the physiological condition of the skin and the individual biological response.
________________________________________
THERAPDERMA CONCLUSION
The true scientific value of Salicylic Peel 25% does not lie exclusively in the concentration of Salicylic Acid, but in the interaction between the complete formulation, the physicochemical properties of the active ingredient, professional technique and the individual biological response of each patient.
Understanding these principles makes it possible to develop safer, more reproducible and more personalised higher-intensity superficial exfoliation protocols, integrating scientific knowledge into clinical practice based on diagnosis, therapeutic planning and respect for skin physiology.

Indications

When should Salicylic Peel 25% be selected?
The indication for a professional chemical peel should always be based on a comprehensive clinical diagnosis and the definition of specific therapeutic objectives.
Beyond the acid concentration, the decision depends on the biological characteristics of the skin, the degree of sebaceous activity, the condition of the skin barrier, the phototype and the clinical objectives established for each patient.
Within this context, Salicylic Peel 25% may be incorporated when the professional considers a higher-intensity selective superficial exfoliation appropriate, aimed at controlling oily skin, purifying the pilosebaceous environment, promoting epidermal renewal and progressively improving superficial texture and tone irregularities.
Each indication should be established individually, adapting the protocol according to the clinical progression and avoiding standardised treatments.
________________________________________
PATIENT PROFILE
What characteristics are commonly observed?
Salicylic Peel 25% may be considered for appropriately selected patients presenting superficial alterations related to excess sebum, hyperkeratinisation, photodamage or visible tone irregularities.
These patients frequently present one or more of the following characteristics:
✔ oily or seborrhoeic skin;
✔ excessive shine;
✔ enlarged or clogged pores;
✔ open and closed comedones;
✔ acne-prone skin;
✔ appropriately selected acne vulgaris;
✔ irregular skin texture;
✔ congested skin;
✔ superficial post-acne scars;
✔ superficial post-inflammatory hyperpigmentation;
✔ superficial freckles or lentigines;
✔ visible signs of photodamage;
✔ appropriately selected seborrhoeic dermatitis;
✔ the need to progressively improve Skin Quality.
The presence of one or more of these characteristics does not, by itself, constitute an automatic indication. The final decision will always depend on the professional assessment, the exclusion of contraindications and the established therapeutic plan.
________________________________________
MAIN CLINICAL INDICATIONS
Salicylic Peel 25% may be incorporated into professional protocols aimed at:
✔ oily or seborrhoeic skin;
✔ excessive sebaceous secretion;
✔ acne-prone skin;
✔ appropriately selected acne vulgaris;
✔ comedones;
✔ enlarged or clogged pores;
✔ irregular superficial texture;
✔ congested skin;
✔ superficial post-acne scars;
✔ superficial post-inflammatory hyperpigmentation;
✔ superficial freckles and lentigines;
✔ superficial photodamage;
✔ appropriately selected seborrhoeic dermatitis;
✔ moderate actinic keratosis within the applicable professional and legal framework;
✔ progressive improvement of Skin Quality.
Each of these indications requires individualised planning and may be integrated into different therapeutic strategies.
________________________________________
OILY OR SEBORRHOEIC SKIN
Hyperactivity of the sebaceous glands may promote shiny skin with a greater tendency towards clogged pores, the accumulation of impurities and the development of imperfections.
In these cases, Salicylic Peel 25% may form part of protocols designed to promote more intensive purification and the progressive balancing of the pilosebaceous environment.
Common objectives include:
✔ promoting sebum balance;
✔ reducing skin shine;
✔ improving the appearance of pores;
✔ progressively reducing congestion;
✔ promoting visibly cleaner skin;
✔ progressively optimising Skin Quality.
The protocol should always be adapted to the clinical characteristics observed in each patient.
________________________________________
ACNE-PRONE SKIN AND ACNE VULGARIS
The accumulation of keratin and excess sebum may promote progressive obstruction of the pilosebaceous follicle and the development of comedones and imperfections.
When considered appropriate following clinical assessment, Salicylic Peel 25% may be incorporated into protocols aimed at progressively improving the appearance of this type of skin through higher-intensity superficial exfoliation.
Before establishing the indication, the professional should assess:
✔ type and progression of the lesions;
✔ degree of active inflammation;
✔ distribution of the lesions;
✔ presence of open or excoriated lesions;
✔ phototype;
✔ dermatological history;
✔ current pharmacological treatments;
✔ tendency towards post-inflammatory hyperpigmentation;
✔ skin barrier integrity;
✔ clinical objectives.
Treatment planning should always be accompanied by appropriate follow-up and individualised home care.
________________________________________
COMEDONES AND ENLARGED PORES
The progressive accumulation of sebum, keratin and corneocytes may promote the development of comedones, follicular obstruction and increased pore visibility.
When these alterations predominate in the diagnosis, Salicylic Peel 25% may be incorporated into protocols aimed at promoting more intensive purification of the pilosebaceous environment.
Clinical objectives may include:
✔ improving the appearance of enlarged pores;
✔ progressively reducing comedones;
✔ promoting less congested skin;
✔ improving superficial texture;
✔ promoting more even-looking skin;
✔ progressively optimising Skin Quality.
________________________________________
IRREGULAR SKIN TEXTURE
Irregularities of the skin microrelief may be associated with skin congestion, hyperkeratinisation, photodamage and the accumulation of corneocytes.
When these alterations are predominantly superficial, Salicylic Peel 25% may be incorporated into protocols designed to promote more intensive epidermal renewal and progressively improve skin texture.
Clinical objectives may include:
✔ promoting a more even texture;
✔ smoothing the skin microrelief;
✔ improving the appearance of the skin surface;
✔ reducing the sensation of roughness;
✔ promoting visibly more homogeneous skin;
✔ progressively optimising Skin Quality.
________________________________________
SUPERFICIAL POST-ACNE SCARS
Following the resolution of certain acne lesions, superficial texture irregularities and residual tone alterations may persist.
In appropriately selected patients, Salicylic Peel 25% may form part of programmes designed to progressively improve the appearance of superficial post-acne scars.
Common objectives include:
✔ promoting superficial renewal;
✔ progressively smoothing the skin microrelief;
✔ improving skin texture;
✔ optimising the appearance of superficial scars;
✔ promoting visibly more even skin;
✔ progressively optimising Skin Quality.
Deep, depressed or complex scars will require specific assessment and may require complementary procedures.
________________________________________
SUPERFICIAL POST-INFLAMMATORY HYPERPIGMENTATION
Following certain inflammatory lesions, visible tone alterations may persist.
When these alterations are superficial and the patient has been appropriately selected, Salicylic Peel 25% may be incorporated into protocols aimed at promoting greater visual skin tone uniformity.
Clinical objectives may include:
✔ progressively improving the appearance of post-inflammatory marks;
✔ promoting epidermal renewal;
✔ reducing visible tone irregularities;
✔ promoting visibly more homogeneous skin;
✔ progressively optimising Skin Quality.
Progress will depend on daily photoprotection, inflammation control and adherence to home care.
________________________________________
SUPERFICIAL FRECKLES AND LENTIGINES
Freckles and certain superficial lentigines may be associated with sun exposure and an uneven distribution of skin pigmentation.
In appropriately selected patients, and after confirming the benign nature of the lesions, Salicylic Peel 25% may be incorporated into protocols designed to progressively improve their appearance.
Common objectives include:
✔ promoting greater visual tone uniformity;
✔ improving the appearance of superficial pigment irregularities;
✔ promoting controlled epidermal renewal;
✔ progressively improving skin radiance and Skin Quality.
Any pigmented lesion of uncertain diagnosis, recent evolution or atypical characteristics should be medically evaluated before performing the procedure.
________________________________________
SUPERFICIAL PHOTODAMAGE
Cumulative sun exposure may promote irregular texture, visible tone alterations, lentigines and a less even skin appearance.
Within appropriately planned protocols, Salicylic Peel 25% may be incorporated to promote higher-intensity superficial exfoliation and contribute to the progressive improvement of photodamage.
Clinical objectives may include:
✔ promoting epidermal renewal;
✔ improving superficial texture;
✔ promoting greater visual tone uniformity;
✔ improving the appearance of superficial lentigines;
✔ promoting visibly more renewed skin;
✔ progressively optimising Skin Quality.
Photoprotection is an essential component before, during and after the protocol.
________________________________________
SEBORRHOEIC DERMATITIS
Seborrhoeic dermatitis may be associated with alterations of the sebum-rich environment, scaling and variable inflammation.
The manufacturer’s documentation includes this condition among the possible indications for Salicylic Peel 25%.
However, the procedure should only be considered in correctly diagnosed, stabilised cases without active inflammation, erosions, fissures or impairment of the skin barrier.
Professional objectives may include:
✔ promoting the removal of superficial scales;
✔ progressively improving texture;
✔ contributing to the balance of the sebaceous environment;
✔ promoting visibly more even skin.
Active or uncontrolled seborrhoeic dermatitis is incompatible with performing the peel until stabilisation has been achieved.
________________________________________
MODERATE ACTINIC KERATOSIS
The manufacturer’s technical documentation includes moderate actinic keratosis among the possible indications for Salicylic Peel 25%.
As this is a lesion associated with chronic sun damage and with potential medical significance, its diagnosis and treatment should be carried out exclusively by legally authorised healthcare professionals within the applicable scope of practice.
Before considering the procedure, the following should be confirmed:
✔ the medical diagnosis;
✔ the nature of the lesion;
✔ the absence of suspicious signs;
✔ the suitability of the peel within the therapeutic plan;
✔ the possibility of appropriate clinical follow-up.
Salicylic Peel 25% should not be applied to undiagnosed, atypical pigmented or keratotic lesions, or to lesions that have recently changed.
________________________________________
MALE SKIN
Male skin generally presents greater sebaceous activity, a thicker stratum corneum and a greater tendency towards pilosebaceous congestion, ingrown hairs and pseudofolliculitis.
Within appropriately planned protocols, Salicylic Peel 25% may be incorporated to promote higher-intensity selective superficial exfoliation and contribute to the progressive balance of this skin type.
Application should be adapted to shaving habits, avoiding treatment on recently shaved, irritated or injured skin.
________________________________________
CLINICAL TREATMENT OBJECTIVES
The selection of Salicylic Peel 25% should always be based on clearly defined clinical objectives before beginning the protocol.
The most common include:
✔ promoting the progressive balance of excess oil;
✔ purifying the pilosebaceous environment;
✔ improving the appearance of enlarged pores;
✔ progressively reducing comedones;
✔ promoting a more even texture;
✔ improving the appearance of superficial post-acne scars;
✔ progressively improving superficial tone irregularities;
✔ promoting the renewal of photoaged skin;
✔ progressively optimising Skin Quality.
Clearly defining these objectives facilitates treatment planning and enables more accurate clinical evaluation of progress.
________________________________________
CRITERIA FOR SELECTING SALICYLIC PEEL 25%
The decision to use Salicylic Peel 25% should be based on the overall assessment of the patient and the correspondence between the observed clinical characteristics and the established therapeutic objectives.
Before indicating Salicylic Peel 25%, it is advisable to confirm:
✔ that the alterations are predominantly superficial;
✔ that there is a well-defined clinical indication;
✔ that the skin barrier presents adequate integrity;
✔ that the patient has no allergy to Salicylic Acid, aspirin or other salicylates;
✔ that the phototype and pigmentation predisposition have been assessed;
✔ that there has been no recent sun exposure incompatible with the procedure;
✔ that the patient understands the treatment objectives and expected recovery;
✔ that appropriate follow-up can be carried out;
✔ that the protocol is consistent with the expected progression.
Concentration is only one of the elements involved in therapeutic planning and should never be used as an isolated decision-making criterion.
________________________________________
WHEN SHOULD SALICYLIC PEEL 25% BE CHOSEN?
Salicylic Peel 25% may represent an appropriate option when the primary objective is to:
✔ perform higher-intensity selective superficial exfoliation;
✔ promote the balance of oily skin;
✔ purify the pores and the pilosebaceous environment;
✔ progressively reduce comedones;
✔ improve the appearance of enlarged pores;
✔ promote a more even texture;
✔ improve the appearance of superficial post-acne scars;
✔ address correctly diagnosed superficial pigmentary alterations;
✔ progressively improve the appearance of photodamage;
✔ progressively optimise Skin Quality.
The decision should always be based on the clinical diagnosis and the therapeutic objectives established for each patient.
________________________________________
SUMMARY OF THE MAIN INDICATIONS
Salicylic Peel 25% may be considered within professional protocols for appropriately selected patients presenting:
✔ oily or seborrhoeic skin;
✔ excessive sebaceous secretion;
✔ acne-prone skin;
✔ acne vulgaris;
✔ comedones;
✔ enlarged or clogged pores;
✔ irregular superficial texture;
✔ congested skin;
✔ superficial post-acne scars;
✔ superficial post-inflammatory hyperpigmentation;
✔ superficial freckles and lentigines;
✔ superficial photodamage;
✔ stabilised seborrhoeic dermatitis;
✔ moderate actinic keratosis within the applicable healthcare framework;
✔ reduced Skin Quality.
These indications constitute a general clinical guide and should always be interpreted within the context of the individual assessment carried out by the professional.
________________________________________
THERAPDERMA CLINICAL CONCLUSION
Correct indication is one of the fundamental pillars of safe, personalised and clinically consistent treatment.
Salicylic Peel 25% has been developed to be integrated into professional protocols intended for patients who may benefit from higher-intensity selective superficial exfoliation aimed at controlling oily skin, purifying the pilosebaceous environment, promoting epidermal renewal and progressively improving superficial texture and tone irregularities.
Its use should always be based on a rigorous clinical assessment, clearly defined therapeutic objectives and individualised planning adapted to each patient’s biological progression.
As part of the TherapDerma Clinical Ecosystem™, it constitutes a clinical tool designed to be integrated into personalised programmes combining diagnosis, therapeutic planning, photoprotection, home care and continuous follow-up, supporting professional practice based on scientific evidence and respect for skin physiology.

Contraindications

Safety begins before treatment
The decision to perform a professional chemical peel does not depend solely on the existence of a clinical indication. Before beginning any procedure, it is essential to identify situations that may compromise patient safety or alter the expected response to treatment.
Early identification of contraindications helps reduce the risk of complications, establish the most appropriate time to intervene or, where necessary, select a different therapeutic strategy.
In the case of Salicylic Peel 25%, in addition to the general contraindications applicable to any chemical peel, particular attention should be paid to possible hypersensitivity to Salicylic Acid, aspirin (acetylsalicylic acid) and other salicylates, as cross-reactivity may occur.
Due to its higher concentration, it is also especially important to assess the integrity of the skin barrier, phototype, predisposition to post-inflammatory hyperpigmentation, recent treatments and the skin’s recovery capacity.
Safe clinical practice does not consist solely of knowing when to treat, but also of recognising when it is preferable to postpone or avoid the procedure.
________________________________________
ABSOLUTE CONTRAINDICATIONS
The following situations contraindicate the use of Salicylic Peel 25% until the underlying cause has resolved or a new clinical assessment allows treatment to be reconsidered.
________________________________________
PREGNANCY AND BREASTFEEDING
As a precautionary measure, chemical peels are not recommended during pregnancy or breastfeeding.
Although the systemic absorption of topically applied Salicylic Acid is limited, there are insufficient clinical data to recommend its routine use during these stages.
Patient safety should always take precedence over any aesthetic objective.
________________________________________
ALLERGY TO ASPIRIN OR SALICYLATES
This is the main specific contraindication for Salicylic Peel 25%.
The procedure should not be performed in patients with a known history of:
✔ allergy to aspirin (acetylsalicylic acid);
✔ hypersensitivity to salicylates;
✔ previous allergic reactions to Salicylic Acid;
✔ a history of a severe reaction following the use of products containing salicylates.
The presence of any of these factors should lead to exclusion of the procedure or assessment of a different therapeutic alternative.
________________________________________
ACTIVE SKIN INFECTIONS
Salicylic Peel 25% should not be applied to skin presenting active infectious processes, as inflammation and tissue alteration may modify the skin response to the procedure.
The main situations include:
✔ active herpes simplex;
✔ bacterial infections;
✔ viral infections;
✔ fungal infections;
✔ pustular lesions of infectious origin;
✔ any inflammatory process associated with infection.
Treatment may only be reconsidered once the infectious process has completely resolved and the skin has regained its clinical integrity.
________________________________________
WOUNDS AND LOSS OF SKIN INTEGRITY
The procedure should not be performed on areas presenting visible alterations of the skin surface.
This includes:
✔ open wounds;
✔ abrasions;
✔ erosions;
✔ fissures;
✔ excoriations;
✔ recent burns;
✔ sunburn;
✔ areas subjected to surgical or traumatic procedures with incomplete healing.
The skin should be fully recovered before considering any chemical exfoliation procedure.
________________________________________
ACTIVE INFLAMMATORY DERMATOSES
The presence of active inflammatory conditions in the treatment area temporarily contraindicates the peel.
These include:
✔ dermatitis;
✔ eczema;
✔ active psoriasis;
✔ inflammatory rosacea;
✔ contact dermatitis;
✔ uncontrolled seborrhoeic dermatitis;
✔ other dermatoses involving inflammation or alteration of the epidermis.
The procedure may only be reconsidered once the condition has stabilised and clinical assessment confirms skin recovery.
________________________________________
HYPERSENSITIVITY TO THE FORMULATION
Salicylic Peel 25% is contraindicated in patients with a known history of hypersensitivity to Salicylic Acid or any component of the formulation.
Where there is any history of an allergic reaction, significant intolerance or unexpected response to similar procedures, an individual assessment should be carried out before considering treatment.
Previous tolerance to other Beta Hydroxy Acids does not necessarily imply an equivalent response to Salicylic Acid.
________________________________________
EXTREMELY REACTIVE SKIN
In patients with a marked tendency to develop exaggerated skin responses, the professional should carefully assess the suitability of the procedure.
Particularly where there is a history of:
✔ persistent irritation;
✔ repeated episodes of dermatitis;
✔ intolerance to multiple cosmetic products;
✔ intense reactions following superficial procedures;
✔ disproportionate skin sensitivity;
✔ recurrent impairment of the skin barrier.
Due to the higher concentration of Salicylic Peel 25%, in these cases it may be more appropriate to stabilise the skin beforehand, consider a lower concentration or select a different therapeutic strategy according to professional judgement.
________________________________________
UNDIAGNOSED PIGMENTED OR KERATOTIC LESIONS
Salicylic Peel 25% should not be applied to pigmented, keratotic or atypical-looking lesions that have not previously been diagnosed.
The procedure should be postponed where lesions present:
✔ recent changes in size;
✔ alterations in shape or borders;
✔ colour variations;
✔ bleeding;
✔ ulceration;
✔ progressive growth;
✔ new symptoms;
✔ any clinically suspicious characteristic.
In these situations, medical assessment should be requested before considering any aesthetic procedure.
________________________________________
TEMPORARY CONTRAINDICATIONS
Certain circumstances do not permanently contraindicate the use of Salicylic Peel 25%, but make it advisable to delay the procedure until the skin has regained its usual physiological condition.
The decision should always be based on the observed clinical progression and not solely on a predetermined time interval.
________________________________________
RECENT DERMATOLOGICAL OR AESTHETIC TREATMENTS
Before indicating the peel, it is essential to know which procedures have been performed during the previous weeks, as some may temporarily alter the skin response.
Particular assessment will be required in patients who have recently received:
✔ topical or oral retinoids;
✔ other exfoliating agents;
✔ keratolytic treatments;
✔ laser procedures;
✔ skin resurfacing;
✔ dermabrasion or microdermabrasion;
✔ microneedling;
✔ fractional radiofrequency;
✔ intense pulsed light;
✔ other chemical peels;
✔ procedures that have caused erythema, peeling or impairment of the skin barrier.
Salicylic Peel 25% should be postponed until complete skin recovery has been confirmed and there are no clinical signs of residual irritation.
________________________________________
HAIR REMOVAL AND PROCEDURES THAT INCREASE SENSITIVITY
Certain cosmetic techniques may cause temporary alteration of the skin surface and increase sensitivity to the procedure.
These include:
✔ waxing;
✔ threading;
✔ depilatory creams;
✔ electrolysis;
✔ particularly aggressive shaving;
✔ intensive extractions;
✔ other procedures that may sensitise the skin.
Treatment should be postponed until the treated area has fully returned to its usual condition.
________________________________________
RECENT SUN EXPOSURE
It is not advisable to begin a protocol when the skin presents signs of intense sun exposure, sun erythema or a recent tan.
The procedure should also be postponed if the patient anticipates significant exposure during the recovery period and cannot guarantee adequate photoprotection.
Treatment scheduling should always be adapted to the individual clinical context and the risk of developing pigmentation irregularities.
________________________________________
IMPAIRMENT OF THE SKIN BARRIER
Salicylic Peel 25% should not be applied when the skin presents signs of impaired barrier function.
These may include:
✔ intense peeling;
✔ persistent burning sensation;
✔ prolonged erythema;
✔ extreme dryness;
✔ severe tightness;
✔ fissures;
✔ irritation associated with excessive use of home-care active ingredients;
✔ disproportionate sensitivity to touch or commonly used cosmetics.
The procedure should be postponed until the skin has regained an appropriate physiological condition.
________________________________________
SITUATIONS REQUIRING SPECIFIC CLINICAL ASSESSMENT
Certain circumstances do not necessarily represent an absolute contraindication, but require more detailed assessment before deciding whether to perform the procedure.
These include:
✔ history of post-inflammatory hyperpigmentation;
✔ phototypes with a greater predisposition to pigmentation irregularities;
✔ tendency towards hypertrophic or keloid scarring;
✔ systemic diseases that may alter skin repair;
✔ pharmacological treatments that influence the skin response;
✔ history of intense reactions to aesthetic procedures;
✔ poorly controlled diabetes;
✔ immunosuppression;
✔ stabilised seborrhoeic dermatitis;
✔ history of recurrent herpes;
✔ other medical situations requiring additional assessment.
In these cases, the protocol should be individualised following careful assessment of the benefit–risk balance.
________________________________________
MODERATE ACTINIC KERATOSIS
The manufacturer’s technical documentation includes moderate actinic keratosis among the possible indications for Salicylic Peel 25%.
However, as this is a lesion related to chronic sun damage and of potential medical significance, its diagnosis and treatment should be performed exclusively by legally authorised healthcare professionals.
The procedure should not be performed without:
✔ a confirmed medical diagnosis;
✔ exclusion of suspicious lesions;
✔ assessment of the suitability of the peel;
✔ planning of clinical follow-up;
✔ practice within the applicable professional and regulatory framework.
The presence of an undiagnosed lesion contraindicates the procedure until an appropriate medical assessment has been obtained.
________________________________________
PHARMACOLOGICAL TREATMENTS
Reviewing the patient’s regular medication forms part of the pre-treatment assessment.
Particular attention should be paid to medications that may:
✔ increase photosensitivity;
✔ modify the inflammatory response;
✔ alter healing;
✔ increase skin fragility;
✔ interfere with normal recovery processes;
✔ modify coagulation or increase the risk of bleeding following accidental injury.
Where there is any doubt regarding the compatibility of pharmacological treatment with the procedure, assessment by the responsible healthcare professional should be requested before proceeding.
________________________________________
PATIENT COOPERATION
The safety of the procedure also depends on the patient’s ability to correctly follow professional recommendations.
Treatment should be reconsidered where there is a high probability of non-compliance with essential aspects such as:
✔ post-treatment care;
✔ daily use of photoprotection;
✔ temporary discontinuation of incompatible active ingredients;
✔ scheduled follow-up appointments;
✔ instructions relating to home-care products;
✔ communication of any unexpected reaction.
Active patient cooperation is essential to minimise risks and promote appropriate clinical progression.
________________________________________
PRE-PROCEDURE CLINICAL CHECKLIST
Before performing Salicylic Peel 25%, it is advisable to confirm that all essential safety criteria have been verified.
☐ The skin is intact and free from visible lesions.
☐ There are no signs of active skin infection.
☐ There are no inflammatory dermatoses in the treatment area.
☐ The patient is not pregnant or breastfeeding.
☐ There is no history of allergy to aspirin or salicylates.
☐ There is no known history of hypersensitivity to the formulation.
☐ The skin barrier is in suitable condition.
☐ Recent medical and aesthetic treatments have been reviewed.
☐ There has been no recent sun exposure that may interfere with the procedure.
☐ Phototype and the risk of post-inflammatory hyperpigmentation have been assessed.
☐ All pigmented or keratotic lesions in the area have been correctly diagnosed.
☐ The patient understands the recommendations before and after treatment.
☐ The patient can guarantee adequate photoprotection.
☐ There is a clearly established clinical indication.
☐ The intended treatment area, amount, number of layers and contact time have been determined.
☐ The neutraliser and all necessary materials are available to perform the procedure in accordance with the professional protocol.
A systematic assessment before each session helps maintain a high level of safety and supports more consistent clinical decision-making.
________________________________________
CLINICAL DECISION-MAKING IN THE PRESENCE OF A POSSIBLE CONTRAINDICATION
Identification of a contraindication does not always mean permanent cancellation of treatment.
Depending on the clinical situation, the professional may choose one of the following actions:
POSTPONE THE PROCEDURE
When the identified condition is temporary and may resolve over time or through physiological recovery of the skin.
MODIFY THE THERAPEUTIC STRATEGY
When a lower concentration, another acid or an alternative therapeutic approach is more appropriate for the patient’s clinical characteristics or treatment objectives.
REQUEST MEDICAL ASSESSMENT
When there are diseases, pharmacological treatments, pigmented lesions, actinic keratoses or clinical circumstances requiring additional assessment before proceeding.
DO NOT PERFORM THE PROCEDURE
When the potential risk clearly exceeds the expected benefit or suitable safety conditions cannot be guaranteed.
The decision not to treat, when clinically justified, also forms part of responsible professional practice.
________________________________________
PRINCIPLES OF CLINICAL SAFETY
The prevention of complications begins long before application of the peel.
A rigorous clinical assessment makes it possible to:
✔ identify risk situations before treatment;
✔ select the patient correctly;
✔ determine the most appropriate time to intervene;
✔ adapt the intensity and therapeutic strategy;
✔ reduce the likelihood of undesirable responses;
✔ prevent over-exfoliation;
✔ reduce the risk of pigmentation irregularities;
✔ promote safer and more predictable procedures.
Safety should be understood as a continuous process accompanying every stage of treatment, from the initial consultation to final evaluation of the results.
________________________________________
THERAPDERMA CONCLUSION
Identification of contraindications is one of the fundamental pillars of safe clinical practice in professional chemical peels.
In the case of Salicylic Peel 25%, pre-treatment assessment is especially important due to its higher concentration and the need to identify patients with an allergy to Salicylic Acid, aspirin or other salicylates, as well as any impairment of the skin barrier, pigmentation predisposition or situation that may compromise the correct biological response to the procedure.
Before each session, the professional should confirm that the skin is suitable for treatment, that the indication is clearly defined and that the expected benefits fully justify performing the procedure.
Recognising the appropriate time to treat, modify, postpone or even exclude a procedure forms part of responsible clinical decision-making and represents an essential element in minimising risks and promoting safe and predictable progression.
As part of the TherapDerma Clinical Ecosystem™, Salicylic Peel 25% is integrated into a care model based on individual patient assessment, prevention of complications and the rigorous application of protocols grounded in scientific and professional criteria.

Professional Application

A procedure based on precision, clinical observation and personalisation
The quality of a professional chemical peel does not depend solely on the formulation used, but also on the way each session is planned, performed and supervised.
Each treatment should be adapted to the individual characteristics of the skin, the anatomical area treated, the degree of sebaceous activity, the clinical objective and the response observed during the procedure.
Salicylic Peel 25% has been developed exclusively for professional use and should be applied following a structured protocol, in which each phase contributes to ensuring a safe, precise procedure that respects skin physiology.
Due to its higher concentration, it is particularly important to individualise the technique, carefully control the contact time and continuously reassess the clinical response throughout the session.
Correct patient preparation, a uniform application technique and continuous observation of clinical progression are the pillars of controlled and reproducible professional practice.
________________________________________
PRIOR PATIENT PREPARATION
Preparation begins before the day of the session and aims to create the most favourable conditions for carrying out the treatment.
According to the clinical assessment and the patient’s individual characteristics, the professional may temporarily recommend:
✔ avoiding intense sun exposure;
✔ maintaining adequate daily photoprotection;
✔ discontinuing potentially irritating cosmetics where appropriate;
✔ avoiding physical or chemical exfoliants;
✔ avoiding products containing retinoids or exfoliating acids before the session;
✔ not undergoing procedures that may sensitise the skin;
✔ maintaining a gentle home-care routine compatible with the treatment;
✔ optimising the skin barrier beforehand where necessary;
✔ reporting any relevant change in the condition of the skin before the procedure.
These recommendations should be individualised and adapted to the needs of each patient.
Before beginning the session, it is essential to confirm that the skin is stable and meets the appropriate conditions for treatment.
________________________________________
SKIN PREPARATION
Appropriate preparation facilitates a uniform application of the peel and allows greater control of the procedure.
Before beginning, the professional should:
✔ carefully cleanse the treatment area;
✔ remove make-up, sunscreen and other cosmetic residues;
✔ remove superficial impurities;
✔ adequately degrease the skin where indicated by the protocol, particularly in patients with high sebaceous activity;
✔ dry the skin surface completely;
✔ confirm that there are no visible lesions incompatible with the procedure;
✔ confirm that the skin barrier is in suitable condition for application.
All preparation should be carried out gently, avoiding manoeuvres that may unnecessarily increase skin sensitivity.
________________________________________
PROTECTION OF SENSITIVE AREAS
Before applying Salicylic Peel 25%, it is advisable to identify areas requiring specific protection to minimise the risk of accidental contact.
These may include:
✔ the eye contour;
✔ lips and mucous membranes;
✔ corners of the mouth;
✔ nasal folds;
✔ skin folds;
✔ recently manipulated areas;
✔ particularly sensitive areas.
Protection should be applied precisely, without interfering with the surface intended for treatment.
The professional should also prevent the product from coming into contact with the eyes, mucous membranes and any area not included in the protocol.
________________________________________
APPLICATION OF THE PEEL
Salicylic Peel 25% should be applied uniformly and methodically, strictly following the established professional protocol.
Throughout the procedure, it is essential to continuously monitor:
✔ the uniform distribution of the product;
✔ the amount applied to each area;
✔ the number of layers where applicable according to the protocol;
✔ the application sequence;
✔ the contact time;
✔ the observed skin response;
✔ the comfort reported by the patient.
The technique should always be adapted to the individual characteristics of the skin and should never be reproduced automatically in all patients.
________________________________________
ORDER AND UNIFORMITY OF APPLICATION
Following a previously defined working sequence facilitates precise control of the procedure and helps achieve a uniform exposure time across all treated areas.
It is recommended to:
✔ begin with the least sensitive areas according to the professional protocol;
✔ maintain a uniform amount of product;
✔ avoid accumulation in folds or skin depressions;
✔ control proximity to mucous membranes and protected areas;
✔ continuously observe the response of each treated region.
An organised application makes it possible to make adjustments during the session whenever clinical progression indicates that this is advisable.
________________________________________
CONTROL OF CONTACT TIME
Contact time is one of the most important variables in the procedure and should be established according to the professional protocol and the clinical progression observed during the session.
The professional should consider:
✔ the anatomical area treated;
✔ the degree of oiliness;
✔ the thickness of the stratum corneum;
✔ the presence of comedones;
✔ the phototype;
✔ the integrity of the skin barrier;
✔ patient tolerance;
✔ the skin response during application.
The maximum planned time should be understood as a safety limit and not as a target that must necessarily be reached.
Where clinical progression indicates that this is advisable, neutralisation should be performed before the initially planned time.
Under no circumstances should exposure be prolonged in an attempt to achieve a more intense response.
________________________________________
CLINICAL OBSERVATION DURING THE SESSION
The skin response may vary between patients and even between different areas of the same person.
For this reason, clinical observation should be maintained throughout the procedure.
The professional should monitor in particular:
✔ the appearance of erythema;
✔ the degree of frosting where applicable according to the formulation and protocol;
✔ the sensation of heat or stinging reported by the patient;
✔ the uniformity of the response;
✔ possible differences between anatomical regions;
✔ any change indicating that the procedure should be modified or discontinued.
The observed clinical progression should always take precedence over the initial session plan.
________________________________________
CRITERIA FOR ENDING THE APPLICATION
Application should be discontinued when:
✔ the intended clinical response has been achieved;
✔ the time established in the protocol has been completed;
✔ the patient experiences significant discomfort;
✔ an excessive or unexpected response occurs;
✔ the professional considers that continuing may increase the risk.
Ending the procedure at the appropriate time is an essential part of responsible clinical practice.
________________________________________
NEUTRALISATION
Neutralisation is an essential phase of the procedure and should be carried out using only the TherapDerma Neutraliser recommended for professional chemical peels.
Its purpose is to stop the activity of the peel in a controlled manner and allow precise control of treatment intensity.
Once the neutralising solution has been applied, the professional should:
✔ cover the entire treated surface uniformly;
✔ pay particular attention to folds and areas where product may accumulate;
✔ completely remove the product following the established protocol;
✔ immediately reassess the skin response before proceeding with post-treatment care.
Neutralisation carried out at the appropriate time is essential to ensure safety, uniformity of the procedure and correct clinical progression.
________________________________________
IMMEDIATE CARE
Once neutralisation has been completed and the product fully removed, the next objective is to restore skin comfort and support the physiological recovery process.
According to the observed response, the professional may apply the post-procedure products included in the TherapDerma protocol and recommend the most appropriate home-care measures.
It is advisable to:
✔ use gentle cleansing products;
✔ apply the recommended repairing products;
✔ maintain adequate skin hydration;
✔ use a broad-spectrum sunscreen daily;
✔ avoid direct sun exposure during the recovery period;
✔ temporarily discontinue potentially irritating cosmetics;
✔ avoid exfoliants and other procedures until the skin has fully recovered;
✔ report any unexpected reaction.
Post-treatment care forms part of the treatment and contributes to promoting progressive, controlled recovery that respects skin physiology.
________________________________________
CLINICAL PROGRESSION AND FOLLOW-UP
Professional assessment does not end with the final application of the peel.
During the following days, progression may vary between patients depending on the individual characteristics of the skin and the response obtained during the session.
During the clinical review, the professional should assess:
✔ the progression of the skin;
✔ tolerance to the procedure;
✔ physiological recovery of the epidermis;
✔ the degree of peeling;
✔ the progression of oiliness;
✔ the appearance of the pores;
✔ improvement in texture;
✔ the progression of superficial tone irregularities;
✔ the need to adapt home care;
✔ the suitability of scheduling a new session.
Each treatment should be individually reassessed before continuing with the therapeutic protocol.
________________________________________
PROFESSIONAL BEST PRACTICES
The application of Salicylic Peel 25% should be integrated into an organised and standardised clinical methodology.
It is advisable to always maintain the following principles:
✔ follow the TherapDerma professional protocol;
✔ respect the technical indications of the product;
✔ adapt the procedure to each patient;
✔ continuously observe the clinical response;
✔ maintain constant communication with the patient;
✔ document each session appropriately;
✔ reassess before scheduling new procedures.
A systematic methodology and precise technique contribute to improving the safety, reproducibility and clinical consistency of each treatment.
________________________________________
ERRORS TO AVOID
During the professional use of Salicylic Peel 25%, particular care should be taken to avoid:
✘ applying the same procedure identically to all patients;
✘ using an excessive amount of product;
✘ allowing product to accumulate in folds or sensitive areas;
✘ unnecessarily prolonging the contact time;
✘ increasing the number of layers without clinical justification;
✘ ignoring differences in response between different anatomical regions;
✘ delaying neutralisation when clinical progression indicates that the procedure should be ended;
✘ applying the peel to skin with active inflammation or open lesions;
✘ combining treatments without respecting the recovery period;
✘ omitting home-care recommendations;
✘ beginning new sessions without prior clinical reassessment.
Preventing these errors forms part of responsible clinical practice and is one of the main factors in maintaining the safety of the procedure.
________________________________________
PROFESSIONAL CHECKLIST
Before considering the procedure complete, confirm that:
☐ The application was carried out uniformly.
☐ The professional protocol was followed.
☐ The contact time was correctly controlled.
☐ Neutralisation was carried out correctly.
☐ The product was completely removed.
☐ The immediate skin response was assessed.
☐ The indicated post-procedure care was applied.
☐ The patient received clear home-care instructions.
☐ The session was correctly documented.
☐ A clinical review was scheduled where necessary.
A systematic check at the end of each session supports continuity of care, facilitates clinical follow-up and contributes to maintaining high professional quality standards.
________________________________________
THERAPDERMA CONCLUSION
The correct application of a professional chemical peel requires much more than appropriate technique. It requires planning, continuous clinical observation and the ability to adapt each decision to the individual biological response of the skin.
Salicylic Peel 25% has been developed to be integrated into structured professional protocols, in which every phase—from initial preparation to clinical follow-up—contributes to maintaining high standards of safety, technical precision and therapeutic consistency.
Its higher concentration makes it particularly important to individualise the procedure and carefully control the contact time, neutralisation and clinical progression throughout the session, allowing each treatment to be adapted to the specific needs of each patient.
As part of the TherapDerma Clinical Ecosystem™, Salicylic Peel 25% is a tool designed to support personalised, reproducible and scientifically based treatments, in which diagnosis, technique, clinical reassessment and respect for skin physiology form the basis for progressively optimising Skin Quality.

Clinical Protocols

Personalised strategies for different therapeutic objectives
Salicylic Peel 25% may be integrated into different aesthetic medicine programmes whenever there is an appropriate clinical indication and the patient has been correctly selected.
There is no single protocol suitable for every case. Planning should be adapted to the biological characteristics of the skin, the degree of sebaceous activity, the phototype, the condition of the skin barrier, the established therapeutic objectives and the clinical progression observed between sessions.
Due to its higher concentration, each procedure should carefully individualise the treatment area, the amount applied, the number of layers where appropriate, the contact time and the recovery intervals.
The protocols presented below constitute general guidance intended to facilitate therapeutic planning and should always be applied according to professional judgement and the official TherapDerma technical instructions.
________________________________________
SEBUM REGULATION PROTOCOL
Objective
To promote the progressive control of excess oiliness and improve the balance of oily skin through higher-intensity superficial exfoliation with keratolytic, purifying and sebum-regulating action.
It may be considered when there is
✔ oily skin;
✔ seborrhoeic skin;
✔ excessive skin shine;
✔ increased sebaceous production;
✔ enlarged or clogged pores;
✔ congested skin;
✔ insufficient response to lower-intensity superficial protocols, where there is a clinical indication.
Clinical objectives
• Promote the balance of sebaceous secretion.
• Progressively reduce surface shine.
• Purify the pilosebaceous environment.
• Improve the overall appearance of oily skin.
• Promote a more even appearance.
• Progressively optimise Skin Quality.
Continuation of treatment should be established according to the observed clinical progression, always reassessing tolerance, recovery of the skin barrier and the objectives achieved.
________________________________________
PORE PURIFICATION PROTOCOL
Objective
To promote the progressive removal of corneocytes, sebum, keratinous material and impurities accumulated within the pilosebaceous environment, contributing to visibly cleaner and less congested skin.
It may be considered when there is
✔ clogged pores;
✔ enlarged pores;
✔ open comedones;
✔ closed comedones;
✔ blackheads;
✔ uneven texture;
✔ superficial sebum accumulation;
✔ congested skin.
Clinical objectives
• Promote more intensive pore purification.
• Reduce follicular congestion.
• Improve the appearance of comedones.
• Visually refine skin texture.
• Progressively reduce pore visibility.
• Progressively optimise Skin Quality.
Progression should be reassessed before modifying the contact time, number of layers, frequency or intensity of the procedure.
________________________________________
PROTOCOL FOR ACNE-PRONE SKIN
Objective
To integrate Salicylic Peel 25% into a professional strategy aimed at progressively improving the appearance of acne-prone skin through exfoliating, keratolytic, purifying and sebum-regulating action of greater superficial intensity.
It may be considered when there is
✔ appropriately selected acne vulgaris;
✔ comedonal tendency;
✔ recurrent imperfections;
✔ excess sebum;
✔ clogged pores;
✔ uneven texture;
✔ oily skin with superficial congestion;
✔ superficial post-inflammatory marks.
Clinical objectives
• Promote a less congested pilosebaceous environment.
• Progressively improve the appearance of imperfections.
• Reduce the accumulation of sebum and keratin.
• Promote the reduction of comedones.
• Improve the appearance of superficial post-inflammatory marks.
• Promote cleaner and more balanced skin.
This protocol should be adapted to the type of acne, the degree of inflammation, the phototype, the medication used and individual tolerance.
Moderate or severe inflammatory forms should be assessed beforehand by a medical professional.
________________________________________
PROTOCOL FOR COMEDONES AND BLACKHEADS
Objective
To promote progressive pore decongestion by reducing the accumulation of keratin, sebum and superficial impurities.
It may be considered when there is
✔ blackheads;
✔ microcomedones;
✔ closed comedones;
✔ clogged pores;
✔ congested skin;
✔ uneven texture;
✔ superficial corneous accumulation.
Clinical objectives
• Promote progressive pore decongestion.
• Improve the appearance of blackheads.
• Reduce superficial keratin accumulation.
• Refine skin texture.
• Promote visibly cleaner skin.
• Support professional oily-skin control programmes.
Where professional extractions are incorporated, they should only be performed when clinically indicated and while respecting skin integrity.
________________________________________
PORE REFINEMENT PROTOCOL
Objective
To progressively improve the appearance of enlarged or visible pores through oil regulation, follicular purification and superficial epidermal renewal.
It may be considered when there is
✔ enlarged pores;
✔ visible pores;
✔ excess sebum;
✔ uneven texture;
✔ congested skin;
✔ comedones;
✔ loss of superficial uniformity.
Clinical objectives
• Visually reduce the appearance of pores.
• Promote a more refined texture.
• Improve sebaceous balance.
• Reduce follicular congestion.
• Progressively optimise Skin Quality.
The anatomical size of a pore cannot be permanently changed. The objective is to reduce its visibility through sebum control, follicular decongestion and the progressive improvement of skin texture.
________________________________________
TEXTURE IMPROVEMENT PROTOCOL
Objective
To progressively optimise the skin microrelief through higher-intensity selective superficial exfoliation.
It may be considered when there is
✔ uneven texture;
✔ a rough surface;
✔ corneous accumulation;
✔ visible pores;
✔ comedones;
✔ oily or congested skin;
✔ superficial irregularities associated with photodamage;
✔ superficial post-acne scars.
Clinical objectives
• Progressively refine texture.
• Promote a more even surface.
• Reduce the sensation of roughness.
• Visually smooth the skin microrelief.
• Improve the visual clarity of the skin.
• Progressively optimise Skin Quality.
Each session should be reassessed before continuing with the protocol.
________________________________________
PROTOCOL FOR SUPERFICIAL POST-ACNE SCARS
Objective
To promote the progressive improvement of the appearance of superficial post-acne scars through carefully controlled chemical exfoliation programmes.
It may be considered when there is
✔ superficial post-acne scars;
✔ mild irregularities of the skin microrelief;
✔ residual superficial marks;
✔ post-inflammatory tone irregularities;
✔ uneven texture;
✔ loss of visual uniformity.
Clinical objectives
• Promote progressive epidermal renewal.
• Improve the appearance of the superficial microrelief.
• Progressively refine texture.
• Optimise the appearance of superficial scars.
• Promote more even skin.
• Integrate treatment into Skin Quality programmes.
Deep, depressed or complex scars require specific assessment and may require complementary procedures.
________________________________________
PROTOCOL FOR SUPERFICIAL POST-INFLAMMATORY HYPERPIGMENTATION
Objective
To promote the progressive improvement of superficial tone irregularities that may persist following inflammatory processes or acne lesions.
It may be considered when there is
✔ superficial post-inflammatory hyperpigmentation;
✔ dark post-acne marks;
✔ visibly uneven tone;
✔ altered superficial texture;
✔ oily skin prone to new imperfections;
✔ loss of visual uniformity.
Clinical objectives
• Promote greater visual tone uniformity.
• Progressively improve the appearance of post-inflammatory marks.
• Promote controlled epidermal renewal.
• Optimise the visual clarity of the skin.
• Promote visibly more homogeneous skin.
• Integrate treatment into Skin Quality programmes.
Planning should always consider the phototype, pigmentary predisposition, control of inflammation and strict adherence to photoprotection.
________________________________________
PROTOCOL FOR SUPERFICIAL FRECKLES AND LENTIGINES
Objective
To progressively improve the appearance of correctly diagnosed superficial pigmentary irregularities through controlled epidermal renewal.
It may be considered when there is
✔ freckles;
✔ benign superficial lentigines;
✔ uneven tone associated with sun exposure;
✔ superficial photodamage;
✔ loss of radiance and visual uniformity.
Clinical objectives
• Promote greater visual tone uniformity.
• Progressively improve the appearance of superficial pigmentation.
• Promote renewal of the epidermal surface.
• Promote visibly more radiant skin.
• Progressively optimise Skin Quality.
Before the procedure, the benign nature of the lesions should be confirmed. Any atypical, changing or undiagnosed pigmented lesion should be medically assessed.
________________________________________
PROTOCOL FOR SUPERFICIAL PHOTODAMAGE
Objective
To promote progressive epidermal renewal and improve the appearance of superficial alterations associated with cumulative sun exposure.
It may be considered when there is
✔ uneven texture associated with photodamage;
✔ visibly uneven tone;
✔ freckles or superficial lentigines;
✔ a rough skin surface;
✔ loss of radiance;
✔ visible signs of superficial photoageing.
Clinical objectives
• Promote epidermal renewal.
• Progressively improve texture.
• Promote greater visual tone uniformity.
• Optimise the appearance of superficial lentigines.
• Promote visibly more renewed skin.
• Progressively improve Skin Quality.
Daily photoprotection and prevention of further intense exposure are essential components of the protocol.
________________________________________
PROTOCOL FOR STABILISED SEBORRHOEIC DERMATITIS
Objective
To promote the controlled removal of superficial scales and contribute to the progressive balance of the sebum-rich environment in appropriately selected patients.
It may be considered when there is
✔ a confirmed diagnosis of seborrhoeic dermatitis;
✔ clinically stabilised disease;
✔ superficial scaling without active inflammation;
✔ excess oiliness;
✔ uneven texture associated with scale accumulation.
Clinical objectives
• Promote the progressive removal of superficial scales.
• Improve skin texture.
• Contribute to the balance of the sebaceous environment.
• Promote visibly more even skin.
• Progressively optimise comfort and Skin Quality.
The procedure should not be performed where there is active inflammation, intense erythema, fissures, erosions, significant itching or impairment of the skin barrier.
________________________________________
PROTOCOL FOR MODERATE ACTINIC KERATOSIS
Objective
To integrate Salicylic Peel 25% into a professional strategy intended for correctly diagnosed lesions associated with chronic sun damage.
It may only be considered when there is
✔ a confirmed medical diagnosis of moderate actinic keratosis;
✔ a favourable assessment by a legally authorised healthcare professional;
✔ absence of suspicious clinical signs;
✔ a specific indication within a therapeutic plan;
✔ the possibility of clinical follow-up.
Clinical objectives
• Promote controlled exfoliation of the keratotic surface.
• Progressively improve superficial texture.
• Integrate the procedure into an individualised medical strategy.
• Facilitate structured monitoring of progression.
This protocol should be performed exclusively by legally authorised healthcare professionals and within the applicable professional and regulatory framework.
Salicylic Peel 25% should not be applied to undiagnosed, atypical or suspicious lesions.
________________________________________
PROTOCOL FOR MALE SKIN
Objective
To adapt the sebum-regulating, keratolytic and purifying action of Salicylic Peel 25% to the specific characteristics of male skin.
It may be considered when there is
✔ high sebaceous production;
✔ enlarged pores;
✔ blackheads;
✔ uneven texture;
✔ pseudofolliculitis;
✔ ingrown hairs;
✔ shaving-related imperfections;
✔ a thickened stratum corneum.
Clinical objectives
• Promote the balance of sebaceous secretion.
• Improve the appearance of ingrown hairs.
• Reduce follicular congestion.
• Progressively refine texture.
• Promote cleaner and more even skin.
Planning should be adapted to shaving frequency and the clinical condition of the skin. The procedure should not be performed immediately after aggressive shaving or on irritated skin.
________________________________________
PROTOCOL FOR BODY ACNE
Objective
To integrate Salicylic Peel 25% into protocols designed to progressively improve the appearance of body acne, follicular congestion and residual superficial marks.
Areas that may be considered
✔ back;
✔ shoulders;
✔ chest;
✔ décolletage in carefully selected cases;
✔ other areas with high sebaceous activity.
It may be considered when there is
✔ appropriately selected body acne;
✔ comedones;
✔ appropriately assessed superficial folliculitis;
✔ excess oiliness;
✔ clogged pores;
✔ uneven texture;
✔ superficial post-inflammatory hyperpigmentation;
✔ superficial post-acne scars.
Clinical objectives
• Promote the balance of sebaceous activity.
• Promote follicular purification.
• Progressively improve the appearance of body acne.
• Reduce superficial congestion.
• Improve the appearance of superficial marks and scars.
• Optimise body texture and Skin Quality.
The treatment area, amount of product, contact time and frequency should be individualised. Due to the larger body surface, it may be appropriate to treat areas sequentially.
________________________________________
SKIN QUALITY PROTOCOL FOR OILY AND PHOTOAGED SKIN
Objective
To integrate Salicylic Peel 25% into a comprehensive programme intended to progressively optimise the Skin Quality of oily, acne-prone, photoaged skin or skin with superficial tone irregularities.
Areas of action
✔ oiliness;
✔ pores;
✔ comedones;
✔ texture;
✔ superficial post-acne scars;
✔ post-inflammatory hyperpigmentation;
✔ superficial photodamage;
✔ visual uniformity;
✔ skin clarity;
✔ Skin Quality.
Therapeutic integration
Where there is an appropriate clinical indication, Salicylic Peel 25% may be incorporated together with:
✔ personalised mesotherapy;
✔ sebum-regulating protocols;
✔ depigmenting protocols;
✔ PDRN;
✔ soothing and regenerating active ingredients;
✔ blue LED therapy;
✔ red LED therapy;
✔ compatible medical-aesthetic technologies;
✔ professional home-care cosmetics.
The combination of procedures should be carefully planned, always respecting recovery of the skin barrier and the physiological intervals between treatments.
________________________________________
THERAPDERMA COMBINED PROTOCOLS™
Integration into a comprehensive therapeutic strategy
Where there is an appropriate clinical indication, Salicylic Peel 25% may be incorporated into multidisciplinary programmes intended to progressively improve oily, acne-prone, photoaged skin or skin with superficial tone irregularities through a comprehensive approach.
Options that may be combined sequentially include:
✔ personalised mesotherapy;
✔ sebum-regulating protocols;
✔ depigmenting protocols;
✔ PDRN;
✔ soothing and regenerating active ingredients;
✔ blue LED therapy;
✔ red LED therapy;
✔ biostimulation;
✔ compatible medical-aesthetic technologies;
✔ professional home-care cosmetics;
✔ skin-barrier recovery programmes.
The selection of each procedure should always correspond to a specific clinical objective and the individual progression of each patient.
________________________________________
EXAMPLE OF THERAPDERMA INTEGRATION™
Advanced Purifying & Renewal Protocol
Objective
To promote progressively less oily, less congested, more even and visibly renewed skin through a sequential professional strategy.
Phase 1 — Exfoliation, purification and renewal
Salicylic Peel 25%
Objectives:
✔ remove accumulated corneocytes;
✔ promote more intensive pore purification;
✔ progressively regulate excess sebum;
✔ improve texture and superficial tone irregularities;
✔ prepare the skin for subsequent phases.
Phase 2 — Regulation, regeneration and skin comfort
Mesotherapy, PDRN or professional cosmetics selected according to the diagnosis.
Objectives:
✔ complement the sebum-regulating or regenerating action;
✔ promote skin comfort;
✔ support recovery of the skin barrier;
✔ progressively improve the overall appearance of the skin.
Phase 3 — Photobiomodulation
LED therapy selected according to the clinical objectives.
Objectives:
✔ support protocols for acne-prone skin;
✔ promote comfort and recovery;
✔ complement the overall therapeutic strategy.
The sequence and intervals between procedures should be individualised.
________________________________________
THERAPDERMA CLINICAL LADDER™
Individualised treatment selection
The TherapDerma Clinical Ladder™ facilitates selection of the most appropriate strategy according to the clinical needs and progression of each patient.
Initial BHA Level
Salicylic Peel 15%
It may be considered when the objective is to:
✔ progressively regulate excess sebum;
✔ improve the appearance of pores;
✔ promote superficial decongestion;
✔ cosmetically treat comedones;
✔ support protocols for acne-prone skin;
✔ develop periodic maintenance programmes;
✔ progressively optimise Skin Quality.
Advanced BHA Level
Salicylic Peel 25%
It may be considered when the objective is to:
✔ perform higher-intensity superficial exfoliation;
✔ promote more intensive purification of the pilosebaceous environment;
✔ address enlarged pores and more marked congestion;
✔ improve the appearance of superficial post-acne scars;
✔ treat correctly diagnosed superficial pigmentary irregularities;
✔ promote the renewal of photoaged skin;
✔ progressively optimise texture, tone and Skin Quality.
Therapeutic progression should always correspond to the patient’s clinical progression.
Progression from Salicylic Peel 15% to Salicylic Peel 25% should never be automatic. It should be justified according to the diagnosis, therapeutic objectives, recovery of the skin barrier, tolerance and the clinical response obtained.
________________________________________
PROTOCOL PERSONALISATION
Each patient presents different biological and clinical characteristics.
For this reason, therapeutic planning should be individualised during every session.
Personalisation may involve adapting:
✔ the extent of the treatment area;
✔ the contact time;
✔ the amount of product;
✔ the number of layers where included in the protocol;
✔ the treatment sequence;
✔ the frequency of sessions;
✔ the combination with other procedures;
✔ home care;
✔ the photoprotection plan;
✔ recovery periods.
Protocol flexibility makes it possible to optimise the therapeutic response while always respecting skin physiology.
________________________________________
CRITERIA FOR MODIFYING OR DISCONTINUING THE PROGRAMME
During follow-up, the therapeutic strategy may be modified whenever clinical progression indicates that this is advisable.
Situations that may justify adaptation include:
✔ slower recovery than expected;
✔ prolonged skin sensitivity;
✔ persistent erythema;
✔ excessive peeling;
✔ impairment of the skin barrier;
✔ development of post-inflammatory hyperpigmentation;
✔ insufficient therapeutic response;
✔ increased inflammation;
✔ changes in medication or home-care routine;
✔ recent sun exposure;
✔ development of new clinical circumstances;
✔ achievement of the therapeutic objectives.
Following the corresponding reassessment, the professional may:
• maintain the protocol;
• reduce the intensity;
• reduce the contact time;
• reduce the number of layers;
• increase the interval between sessions;
• modify the home-care routine;
• reinforce photoprotection;
• integrate complementary procedures;
• temporarily prioritise recovery of the skin barrier;
• replace Salicylic Peel 25% with a lower concentration;
• temporarily or permanently discontinue treatment.
Modifying a protocol when required by the clinical situation is a professional decision based on safety, individualisation and scientific evidence.
________________________________________
THERAPDERMA CONCLUSION
Clinical protocols provide guidance for structuring treatment, but never replace professional judgement or the individual assessment of each patient.
Salicylic Peel 25% makes it possible to develop personalised higher-intensity superficial exfoliation programmes aimed at controlling oiliness, purifying the pilosebaceous environment, improving the appearance of comedones and enlarged pores, refining texture and promoting greater visual tone uniformity.
It may also be integrated into protocols intended for photodamage, post-inflammatory hyperpigmentation, freckles, lentigines and superficial post-acne scars where there is an appropriate clinical indication.
As part of the TherapDerma Clinical Ecosystem™, each protocol should evolve through continuous reassessment, therapeutic personalisation and the rational integration of complementary procedures, allowing the development of progressive, reproducible treatments based on scientific criteria.

Therapderma™ Combinations

Integrated protocols to enhance therapeutic planning
Modern aesthetic medicine is based on the strategic integration of different procedures, carefully selected and sequenced according to the diagnosis, the biological characteristics of the skin and the therapeutic objectives of each patient.
Within this context, Salicylic Peel 25% may be incorporated as one phase of personalised programmes aimed at the professional treatment of oily, acne-prone, photoaged skin or skin with superficial tone irregularities, promoting higher-intensity superficial exfoliation, the progressive regulation of excess sebum, purification of the pilosebaceous environment and optimisation of Skin Quality.
Each combination should address a specific clinical objective, always respecting physiological recovery times, skin barrier function and the progression observed between procedures.
Within the TherapDerma Clinical Ecosystem™, Salicylic Peel 25% is an advanced tool that may be integrated with other professional solutions to develop fully individualised protocols.
________________________________________
SALICYLIC PEEL 25% + PERSONALISED MESOTHERAPY
Intensive epidermal purification and targeted treatment
Once physiological skin recovery has been completed, Salicylic Peel 25% may be integrated with personalised mesotherapy protocols when clinically indicated.
The selected formulation will always depend on the therapeutic objectives, the physiological condition of the skin and the individual needs of the patient.
Objectives of the combination
✔ complement professional programmes for oily and photoaged skin;
✔ promote the progressive balance of sebaceous secretion;
✔ support protocols for acne-prone skin;
✔ complement depigmentation programmes;
✔ progressively optimise Skin Quality;
✔ improve skin texture and visual uniformity;
✔ incorporate soothing, regenerating, depigmenting or sebum-regulating active ingredients according to the clinical indication.
Mesotherapy should only be introduced once the skin barrier has recovered adequately.
________________________________________
SALICYLIC PEEL 25% + SEBUM-REGULATING PROTOCOLS
Progressive regulation of the pilosebaceous environment
When the main objective is to control excess oiliness and reduce the tendency towards congestion, Salicylic Peel 25% may be integrated with professional sebum-regulating solutions.
Objectives of the combination
✔ promote the progressive balance of sebum;
✔ reduce surface shine;
✔ promote a less congested pilosebaceous environment;
✔ improve the appearance of pores;
✔ reduce the recurrence of comedones;
✔ maintain visibly cleaner and more balanced skin.
The selection of active ingredients and the timing of application should be established according to the observed clinical progression.
________________________________________
SALICYLIC PEEL 25% + PDRN
Renewal, regeneration and planned recovery
When the therapeutic objective includes improving the overall quality of oily skin presenting superficial post-acne scars, residual pigmentary irregularities, superficial photoageing or impaired skin barrier function, Salicylic Peel 25% may form part of a sequential strategy that subsequently incorporates professional PDRN-based solutions.
Objectives of the combination
✔ promote the physiological recovery of the skin;
✔ complement programmes for superficial post-acne scars;
✔ complement depigmentation protocols;
✔ progressively optimise Skin Quality;
✔ integrate personalised regenerative strategies;
✔ promote more even and healthier-looking skin.
Each procedure should only be incorporated after confirming favourable clinical progression.
________________________________________
SALICYLIC PEEL 25% + SKIN BIOSTIMULATION
Preparing the skin for a regenerative strategy
Biostimulation procedures may be incorporated into personalised programmes designed to optimise Skin Quality.
Where there is an appropriate clinical indication, Salicylic Peel 25% may be used as a preliminary phase of epidermal renewal and superficial purification.
Objectives of the combination
✔ promote structured therapeutic planning;
✔ initially improve texture and superficial congestion;
✔ progressively prepare the skin for subsequent procedures;
✔ integrate regenerative strategies;
✔ develop personalised protocols;
✔ optimise overall skin quality.
Biostimulation should only be incorporated once skin recovery is complete.
________________________________________
SALICYLIC PEEL 25% + BLUE LED THERAPY
Support for acne-prone skin protocols
Blue LED therapy may be incorporated as a complementary procedure within personalised programmes for oily or acne-prone skin.
Objectives of the combination
✔ complement professional protocols for acne-prone skin;
✔ promote a more balanced skin environment;
✔ support the progressive control of imperfections;
✔ improve therapeutic continuity between sessions;
✔ complement the purifying action of Salicylic Peel 25%;
✔ integrate into comprehensive sebum-regulation programmes.
Treatment parameters should be individualised for each patient.
________________________________________
SALICYLIC PEEL 25% + RED LED THERAPY
Recovery, comfort and therapeutic continuity
Red LED therapy may be incorporated into protocols designed to promote physiological recovery and skin comfort following exfoliation procedures.
Objectives of the combination
✔ support physiological recovery;
✔ promote skin comfort;
✔ support recovery of the skin barrier;
✔ complement programmes for superficial post-acne scars;
✔ optimise clinical progression between sessions;
✔ promote therapeutic continuity.
Red LED therapy does not replace post-treatment care or photoprotection.
________________________________________
SALICYLIC PEEL 25% + RADIOFREQUENCY
Superficial renewal and complementary technology
Radiofrequency may be incorporated, where there is an appropriate clinical indication, into programmes designed to optimise Skin Quality.
Following adequate physiological recovery, Salicylic Peel 25% may form part of a sequential therapeutic strategy.
Objectives of the combination
✔ integrate epidermal renewal into comprehensive Skin Quality programmes;
✔ progressively improve texture;
✔ promote structured therapeutic planning;
✔ integrate complementary technologies;
✔ adapt treatment to individual needs.
Radiofrequency should not be applied to irritated skin or skin with active inflammation.
________________________________________
SALICYLIC PEEL 25% + DEPIGMENTATION PROTOCOLS
Epidermal renewal and progressive improvement of visual tone uniformity
In appropriately selected patients presenting superficial post-inflammatory hyperpigmentation, freckles, superficial lentigines or tone irregularities, Salicylic Peel 25% may be incorporated into a sequential strategy.
Objectives of the combination
✔ promote epidermal renewal;
✔ progressively improve visual tone uniformity;
✔ complement depigmentation protocols;
✔ promote greater radiance;
✔ progressively optimise Skin Quality;
✔ maintain the physiological balance of the skin.
Planning should always take into account the phototype and the risk of post-inflammatory hyperpigmentation.
________________________________________
SALICYLIC PEEL 25% + PROFESSIONAL HOME CARE COSMETICS
Treatment continuity also takes place at home
The results of a professional programme also depend on compliance with the home-care treatment.
The programme may include:
✔ gentle, non-comedogenic cleansing products;
✔ professional cosmetics adapted for oily skin;
✔ sebum-regulating active ingredients where indicated;
✔ soothing and repairing products;
✔ moisturisers compatible with acne-prone skin;
✔ professional depigmenting products where appropriate;
✔ daily broad-spectrum photoprotection;
✔ products designed to maintain skin barrier function.
Each routine should be individualised according to the clinical progression of the skin.
________________________________________
THERAPDERMA CLINICAL ECOSYSTEM™
A therapeutic approach based on integration
At TherapDerma, we understand that the best clinical outcomes depend on the correct integration of every stage of treatment.
Each procedure forms part of a comprehensive strategy in which diagnosis, treatment, recovery, follow-up and home care work together in a coordinated manner.
Example of integrated planning
Clinical diagnosis

Assessment of skin type, sebaceous activity, phototype, pigmentary irregularities, photoageing and skin barrier function

Definition of therapeutic objectives

Salicylic Peel 25%

Recovery and clinical reassessment

Personalised mesotherapy · PDRN · Sebum-regulating or depigmentation protocols (where clinically indicated)

LED therapy or compatible medical-aesthetic technologies

Professional home-care cosmetics

Clinical follow-up

Personalised maintenance programme
Each stage should be individualised according to the observed clinical progression.
________________________________________
BENEFITS OF INTEGRATED PROTOCOLS
Integrating Salicylic Peel 25% into personalised therapeutic programmes makes it possible to:
✔ facilitate therapeutic planning;
✔ address different components of oily and photoaged skin;
✔ integrate procedures within a coherent clinical strategy;
✔ progressively control oiliness and congestion;
✔ improve the appearance of pores, comedones and superficial irregularities;
✔ complement depigmentation and regenerative protocols;
✔ prepare the skin for subsequent stages;
✔ adapt each stage according to clinical progression;
✔ promote continuity of care;
✔ coordinate in-clinic treatments with home-care routines;
✔ progressively optimise Skin Quality.
________________________________________
CLINICAL SUMMARY
Clinical objective Combination that may be considered
Sebum regulation Salicylic Peel 25% + Personalised Mesotherapy
Oil control Salicylic Peel 25% + Sebum-Regulating Protocol
Acne-prone skin Salicylic Peel 25% + Blue LED Therapy
Recovery and skin comfort Salicylic Peel 25% + Red LED Therapy
Regeneration and superficial scars Salicylic Peel 25% + PDRN
Skin Quality programmes Salicylic Peel 25% + Biostimulation
Technological integration Salicylic Peel 25% + Radiofrequency
Depigmentation programmes Salicylic Peel 25% + Depigmentation Protocol
Therapeutic continuity Salicylic Peel 25% + Professional Home Care Cosmetics
All combinations should be planned on an individual basis.
________________________________________
PRINCIPLES OF SAFE COMBINATION
Before combining Salicylic Peel 25% with any other procedure, the following should be confirmed:
✔ a clearly defined therapeutic objective;
✔ adequate recovery of the skin barrier;
✔ absence of persistent irritation;
✔ absence of significant active inflammation;
✔ compatibility between procedures;
✔ respect for physiological recovery periods;
✔ low risk of cumulative sensitisation;
✔ compliance with home-care instructions;
✔ reassessment before each new stage.
The accumulation of procedures alone does not constitute an advanced therapeutic strategy.
________________________________________
COMBINATIONS REQUIRING SPECIAL CAUTION
Combinations with potentially irritating procedures should be planned carefully.
These include:
✔ other chemical peels;
✔ professional retinoids;
✔ microneedling;
✔ dermabrasion or microdermabrasion;
✔ fractional or ablative lasers;
✔ intensive resurfacing procedures;
✔ waxing;
✔ aggressive extractions;
✔ highly exfoliating home-care cosmetics.
These interventions should not be performed on skin presenting erythema, desquamation or impairment of the skin barrier.
________________________________________
THERAPDERMA PHILOSOPHY
A clinical strategy, not a sum of procedures
At TherapDerma, we understand that every treatment forms part of a much broader therapeutic process.
The true clinical value lies in correctly integrating each stage of treatment, adapting it to the biological progression of each patient through personalised planning based on scientific criteria.
________________________________________
THERAPDERMA CONCLUSION
The intelligent combination of procedures is one of the pillars of modern aesthetic medicine. Its success depends on appropriate planning, the correct sequencing of each stage and the ability to continuously adapt the therapeutic strategy.
Salicylic Peel 25% is a versatile tool that may be integrated, where clinically indicated, with personalised mesotherapy, sebum-regulating protocols, depigmentation protocols, PDRN, biostimulation, LED therapy, compatible technologies and professional home-care cosmetics.
As part of the TherapDerma Clinical Ecosystem™, these combinations make it possible to develop progressive, personalised clinical programmes that are consistent with the physiology of oily, photoaged or acne-prone skin, promoting professional practice based on diagnosis, continuous reassessment and the progressive optimisation of Skin Quality.

Frequently Asked Questions (FAQS)

Clear answers to support clinical practice
During the planning and performance of a professional chemical peel, questions commonly arise regarding patient selection, treatment planning and the integration of the procedure into personalised protocols.
The following questions bring together some of the most frequent queries raised by professionals during clinical practice and TherapDerma training programmes.
Their purpose is to facilitate clinical decision-making and complement the information provided in this catalogue, without replacing individualised diagnosis or the product’s official technical instructions.
________________________________________
WHAT TYPE OF PEEL IS SALICYLIC PEEL 25%?
Salicylic Peel 25% is a professional superficial chemical peel formulated with 25% Salicylic Acid, belonging to the Beta Hydroxy Acid (BHA) group.
It has been developed to promote higher-intensity selective superficial chemical exfoliation, progressive purification of the pilosebaceous environment, gradual regulation of excess oiliness and carefully controlled epidermal renewal, while respecting skin physiology when applied under professional supervision.
Within individualised protocols, it may be incorporated with the aim of progressively promoting:
✔ regulation of oiliness;
✔ pore purification;
✔ reduction of skin congestion;
✔ improvement of superficial texture;
✔ reduction in the appearance of enlarged pores;
✔ improvement of superficial post-acne scars;
✔ greater visual uniformity of skin tone;
✔ progressive improvement of superficial photodamage;
✔ progressive optimisation of Skin Quality.
________________________________________
IN WHICH PATIENTS MAY IT BE CONSIDERED?
Salicylic Peel 25% may be considered when clinical examination identifies characteristics compatible with higher-intensity superficial exfoliation protocols intended for oily, acne-prone, photoaged skin or skin with superficial texture and tone irregularities.
It may commonly be considered in appropriately selected patients presenting:
✔ excess oiliness;
✔ oily or combination skin;
✔ seborrhoeic skin;
✔ enlarged or clogged pores;
✔ open and closed comedones;
✔ appropriately selected acne vulgaris;
✔ irregular skin texture;
✔ congested skin;
✔ superficial post-acne scars;
✔ superficial post-inflammatory hyperpigmentation;
✔ freckles or superficial lentigines;
✔ visible signs of photodamage;
✔ stabilised seborrhoeic dermatitis;
✔ moderate actinic keratosis within the applicable healthcare framework.
The final indication will always depend on the clinical diagnosis, the functional condition of the skin, the phototype and the therapeutic objectives established for each patient.
________________________________________
WHAT IS THE DIFFERENCE BETWEEN SALICYLIC ACID AND ALPHA HYDROXY ACIDS (AHAS)?
Although both AHAs and BHAs are used in professional chemical peels, they have different physicochemical properties and mechanisms of action.
Salicylic Acid belongs to the Beta Hydroxy Acid (BHA) family and has a lipophilic nature that allows it to act preferentially on the sebum-rich environment of the pilosebaceous follicle.
Alpha Hydroxy Acids (AHAs), by contrast, are water-soluble and act mainly on the superficial layers of the epidermis, promoting renewal of the stratum corneum.
The choice between an AHA and a BHA should always be based on:
✔ the diagnosis;
✔ the characteristics of the skin;
✔ the degree of oiliness;
✔ the presence of comedones or congestion;
✔ the therapeutic objective;
✔ individual tolerance;
✔ the phototype;
✔ clinical planning.
________________________________________
WHAT IS THE DIFFERENCE BETWEEN SALICYLIC PEEL 15% AND SALICYLIC PEEL 25%?
Both formulations contain Salicylic Acid and have an affinity for the sebum-rich environment, but they occupy different positions within the TherapDerma Clinical Ladder™.
Salicylic Peel 15% may primarily be considered for:
✔ progressive regulation of oiliness;
✔ superficial pore purification;
✔ oily or acne-prone skin;
✔ comedones and superficial congestion;
✔ periodic maintenance programmes.
Salicylic Peel 25% may be considered when the diagnosis justifies:
✔ higher-intensity superficial exfoliation;
✔ more intensive purification of the pilosebaceous environment;
✔ enlarged or clogged pores;
✔ superficial post-acne scars;
✔ superficial post-inflammatory hyperpigmentation;
✔ freckles and superficial lentigines;
✔ superficial photodamage;
✔ other specific indications included in the technical documentation.
Progression from one concentration to another should never be automatic. The choice will depend on the diagnosis, the integrity of the skin barrier, tolerance, therapeutic objectives and the observed clinical progression.
________________________________________
CAN IT BE USED ON SENSITIVE SKIN?
The indication for Salicylic Peel 25% should always be established following an individualised clinical assessment.
Due to its higher concentration, it is not usually the first option for patients with sensitive or reactive skin, or with impaired skin barrier function.
In these patients, it will be particularly important to assess:
✔ the integrity of the skin barrier;
✔ the presence of erythema;
✔ usual skin sensitivity;
✔ history of skin reactions;
✔ recent procedures;
✔ the use of retinoids or other potentially irritating active ingredients;
✔ the phototype;
✔ predisposition to post-inflammatory hyperpigmentation;
✔ known sensitivity to Salicylic Acid or salicylates.
Where tolerance is uncertain, it may be more appropriate to stabilise the skin beforehand, select a lower concentration or consider an alternative therapeutic strategy.
Correct patient selection remains one of the main factors related to the safety of the procedure.
________________________________________
HOW MANY SESSIONS ARE USUALLY RECOMMENDED?
There is no fixed number of sessions applicable to all patients.
The duration of the programme will depend on various clinical factors, including:
✔ the initial diagnosis;
✔ the degree of oiliness;
✔ the presence of comedones;
✔ the degree of photodamage;
✔ superficial texture or tone irregularities;
✔ the intensity of the protocol performed;
✔ the response observed after each session;
✔ the skin’s recovery capacity;
✔ clinical progression.
Each session should form part of a personalised therapeutic strategy and be decided following the corresponding professional reassessment.
________________________________________
HOW FREQUENTLY CAN IT BE APPLIED?
The interval between sessions should be individualised according to the clinical progression of each patient.
Before scheduling a new application, it will be necessary to confirm that the skin has adequately recovered its physiological condition and that the skin barrier is intact.
To establish the most appropriate frequency, aspects such as the following may be assessed:
✔ the observed skin response;
✔ the degree of recovery;
✔ the intensity of the protocol performed;
✔ the contact time used;
✔ the number of layers applied where appropriate;
✔ the treatment area;
✔ integration with other procedures;
✔ the progression of oiliness, texture and superficial tone irregularities.
A new session is not recommended while signs of irritation, erythema, significant peeling or incomplete recovery persist.
________________________________________
CAN IT BE COMBINED WITH OTHER PROCEDURES?
Yes.
Salicylic Peel 25% may be integrated into personalised therapeutic programmes where there is an appropriate clinical indication and physiological recovery periods have been respected.
Depending on the treatment objectives, it may be combined sequentially with procedures such as:
✔ personalised mesotherapy;
✔ oil-regulating protocols;
✔ depigmentation protocols;
✔ professional PDRN solutions;
✔ biostimulation;
✔ LED therapy;
✔ radiofrequency;
✔ professional home-care cosmetics;
✔ other compatible medical-aesthetic technologies.
The combination should always be planned while respecting recovery of the skin barrier, compatibility between procedures and the risk of cumulative sensitisation.
________________________________________
IS IT MANDATORY TO NEUTRALISE THE PEEL?
Yes.
Salicylic Peel 25% requires neutralisation at the end of the established action time or earlier if the clinical response indicates that this is advisable.
Neutralisation should be carried out using only the TherapDerma Neutraliser indicated for professional chemical peels and following the corresponding technical protocol.
Once the procedure has been completed, complete neutralisation and removal of the product should be verified before beginning post-treatment care.
________________________________________
WHAT CARE SHOULD THE PATIENT FOLLOW AFTER TREATMENT?
Post-treatment care forms part of the treatment and contributes to promoting appropriate skin recovery between sessions.
After each procedure, the professional may recommend a home-care programme adapted to the patient’s needs, which may include:
✔ gentle cleansing products;
✔ personalised professional cosmetics;
✔ hydration adapted to the skin type;
✔ skin-barrier repairing products;
✔ daily broad-spectrum photoprotection;
✔ avoiding direct sun exposure;
✔ temporary discontinuation of retinoids, exfoliating acids and other potentially irritating products;
✔ avoiding physical exfoliants;
✔ avoiding procedures that may compromise skin recovery until physiological regeneration is complete;
✔ not manually removing flakes or peeling skin;
✔ reporting any unexpected or persistent reaction.
Compliance with these recommendations contributes to optimising clinical progression and maintaining continuity of treatment.
________________________________________
CAN IT BE USED THROUGHOUT THE YEAR?
The possibility of performing a chemical peel does not depend solely on the season, but on the clinical assessment and the individual circumstances of each patient.
Before planning treatment, the following should be assessed:
✔ skin phototype;
✔ recent sun exposure;
✔ anticipated sun exposure;
✔ individual risk of pigmentation irregularities;
✔ the treatment area;
✔ the clinical objective;
✔ the patient’s ability to maintain adequate photoprotection.
Due to the greater superficial intensity of Salicylic Peel 25%, planning should be particularly rigorous where there is high sun exposure or difficulty guaranteeing photoprotection.
Where circumstances may compromise skin recovery or increase the risk of post-inflammatory hyperpigmentation, the professional should modify the protocol or temporarily postpone the procedure.
________________________________________
CAN IT FORM PART OF PROGRAMMES FOR ACNE-PRONE SKIN?
Yes.
Where there is an appropriate clinical indication, Salicylic Peel 25% may be incorporated into personalised protocols aimed at progressively improving the appearance of oily or acne-prone skin.
Within these programmes, it may contribute to promoting:
✔ less oily skin;
✔ a progressive reduction in skin congestion;
✔ an improved appearance of pores;
✔ a progressive reduction in comedones;
✔ a more even texture;
✔ visibly cleaner skin;
✔ improvement of superficial post-acne scars;
✔ progressive optimisation of Skin Quality.
The type and severity of acne should be assessed before treatment. Moderate or severe inflammatory forms require medical assessment and may not be compatible with the procedure during certain stages of their progression.
________________________________________
CAN IT BE USED FOR PIGMENTATION AND PHOTODAMAGE?
Salicylic Peel 25% may be considered within professional protocols intended for certain superficial pigmentary irregularities and visible signs of photodamage.
It may contribute to progressively improving the appearance of:
✔ superficial post-inflammatory hyperpigmentation;
✔ freckles;
✔ benign superficial lentigines;
✔ visibly uneven tone;
✔ texture altered by photodamage;
✔ loss of radiance and uniformity.
Before performing the procedure, the diagnosis and the superficial nature of the alteration should be confirmed.
Any atypical, changing or undiagnosed pigmented lesion should be medically assessed before applying the peel.
Photoprotection is an essential part of the protocol.
________________________________________
CAN IT BE USED FOR ACNE SCARS?
Salicylic Peel 25% may be incorporated into protocols designed to progressively improve the appearance of superficial post-acne scars.
Its exfoliating action may contribute to:
✔ promoting epidermal renewal;
✔ smoothing the superficial skin microrelief;
✔ improving skin texture;
✔ promoting greater visual uniformity;
✔ complementing regenerative or Skin Quality programmes.
Deep, depressed, fibrotic or complex scars do not usually respond sufficiently to an isolated superficial peel and may require complementary procedures.
________________________________________
CAN IT BE USED IN SEBORRHOEIC DERMATITIS?
The manufacturer’s technical documentation includes seborrhoeic dermatitis among the possible indications for Salicylic Peel 25%.
However, it may only be considered in correctly diagnosed patients and when the condition is clinically stabilised.
It should not be applied where there is:
✔ active inflammation;
✔ intense erythema;
✔ significant itching;
✔ fissures or erosions;
✔ intense inflammatory scaling;
✔ impairment of the skin barrier.
The indication should be established individually and within the applicable professional scope of practice.
________________________________________
CAN IT BE USED IN MODERATE ACTINIC KERATOSIS?
The manufacturer’s technical documentation includes moderate actinic keratosis among the possible indications for Salicylic Peel 25%.
As this is a lesion associated with chronic sun damage and of potential medical significance, its diagnosis and treatment should be carried out exclusively by legally authorised healthcare professionals.
Before the procedure, there should be:
✔ a confirmed medical diagnosis;
✔ exclusion of suspicious lesions;
✔ a specific indication within a therapeutic plan;
✔ assessment of the benefit–risk balance;
✔ the possibility of clinical follow-up.
Salicylic Peel 25% should not be applied to undiagnosed or atypical lesions, or to lesions that have recently changed.
________________________________________
WHAT IS THE MAIN OBJECTIVE OF SALICYLIC PEEL 25%?
The main objective of Salicylic Peel 25% is to promote higher-intensity selective superficial exfoliation aimed at the progressive control of oiliness, purification of the pilosebaceous environment, epidermal renewal and optimisation of Skin Quality.
Its use may contribute to:
✔ progressively regulating excess sebum;
✔ promoting pore cleansing;
✔ reducing follicular congestion;
✔ improving superficial texture;
✔ reducing the appearance of enlarged pores;
✔ improving superficial post-acne scars;
✔ promoting greater visual uniformity of skin tone;
✔ progressively improving the appearance of photodamage;
✔ complementing personalised professional protocols.
Treatment planning should always be adapted to the specific needs and biological response of each patient.
________________________________________
QUICK SUMMARY
Key concepts regarding Salicylic Peel 25%
✔ Professional superficial chemical peel with 25% Salicylic Acid.
✔ Beta Hydroxy Acid (BHA) with an affinity for the lipid-rich environment of the pilosebaceous follicle.
✔ Promotes higher-intensity selective superficial exfoliation.
✔ Helps regulate excess oiliness.
✔ Contributes to purifying pores and improving the appearance of congested skin.
✔ May promote a more even skin texture.
✔ May be integrated into protocols for superficial post-acne scars.
✔ May contribute to improving certain superficial pigmentary irregularities and photodamage.
✔ Indicated only following an individualised clinical assessment.
✔ May be integrated into personalised TherapDerma Clinical Ecosystem™ protocols.
✔ Compatible with sequential therapeutic strategies where there is a professional indication.
✔ Contraindicated in patients with an allergy to Salicylic Acid, aspirin or other salicylates.
✔ Mandatory neutralisation following the official technical protocol.
✔ Planning, photoprotection, follow-up and clinical reassessment form part of the treatment.
________________________________________
THERAPDERMA CONCLUSION
The frequently asked questions constitute a reference tool designed to facilitate daily clinical practice and resolve the most common queries related to the use of Salicylic Peel 25%.
Beyond the concentration of the formulation, the success of a chemical peel depends on correct patient selection, individualised planning, a rigorous application technique and continuous monitoring of clinical progression.
Within the TherapDerma Clinical Ecosystem™, Salicylic Peel 25% is integrated as a therapeutic tool designed to develop personalised protocols aimed at controlling oiliness, purifying the pilosebaceous environment, promoting epidermal renewal and progressively improving superficial texture and tone irregularities.
Our commitment is to provide solutions supported by scientific knowledge, promoting responsible, personalised aesthetic medicine aimed at achieving progressive, reproducible results that respect skin physiology.

Discover the TherapDerma professional universe
Modern aesthetic medicine requires a comprehensive approach combining scientific knowledge, clinical planning and continuous professional development.
For this reason, Salicylic Peel 25% forms part of the TherapDerma Clinical Ecosystem™, a professional environment that integrates scientific resources, clinical protocols, technologies, training programmes and complementary solutions designed to support professionals at every stage of clinical practice.
In addition to this catalogue, TherapDerma provides a collection of guides, protocols and tools that make it possible to develop personalised, structured treatments based on the available evidence.
________________________________________
THERAPDERMA PEELING COLLECTION™
A collection designed for different clinical objectives
The TherapDerma peel collection brings together different professional solutions that make it possible to select the most appropriate acid and concentration according to the clinical characteristics of each patient.
The range includes different formulations designed to address multiple therapeutic needs, while maintaining a shared philosophy based on treatment personalisation.
Available collection
✔ Glycolic Peel
✔ Lactic Peel
✔ Malic Peel
✔ Mandelic Peel
✔ Salicylic Peel
✔ Pyruvic Peel
✔ TCA Peel
Each formulation has been developed to be integrated into professional protocols adapted to different clinical indications.
In the case of Salicylic Peel, the collection makes it possible to select between different concentrations according to the diagnosis, the desired level of action, skin tolerance and the therapeutic objectives defined for each patient.
Salicylic Peel 15% occupies a position mainly intended for progressive protocols for sebum regulation, superficial purification and maintenance of oily skin.
Salicylic Peel 25% is integrated as a higher-intensity superficial exfoliation option, intended for appropriately selected patients requiring more advanced action on oiliness, pores, comedones, texture, superficial post-acne scars, photodamage and certain superficial tone irregularities.
________________________________________
THERAPDERMA MESOTHERAPY COLLECTION™
Professional solutions for personalised protocols
The TherapDerma mesotherapy collection brings together formulations developed to complement aesthetic medicine programmes adapted to the individual needs of each patient.
It includes solutions intended for different treatment areas, including:
✔ oil regulation;
✔ protocols for acne-prone skin;
✔ professional hydration;
✔ biostimulation;
✔ skin regeneration;
✔ improvement of visual tone uniformity;
✔ body treatments;
✔ hair treatments.
Each formulation forms part of a personalised therapeutic approach and may be integrated into clinical strategies designed by the professional.
In programmes with Salicylic Peel 25%, mesotherapy should only be incorporated after confirming complete recovery of the skin barrier and when there is a specific clinical indication.
________________________________________
THERAPDERMA TECHNOLOGIES™
Technology at the service of clinical practice
TherapDerma medical-aesthetic technologies have been selected to expand the professional’s therapeutic possibilities and complement different treatment programmes.
The collection includes equipment intended for different clinical applications, making it possible to develop protocols adapted to each patient’s objectives.
In protocols with Salicylic Peel 25%, technologies may be incorporated sequentially where there is an appropriate clinical indication and always while respecting physiological skin recovery and the established intervals between procedures.
The combined use of technology and professional procedures facilitates more versatile, organised and personalised clinical practice.
________________________________________
THERAPDERMA CLINICAL PROTOCOLS™
Protocols developed to facilitate clinical planning
TherapDerma provides structured protocols that serve as a guide for organising different treatments within professional practice.
These documents provide a clear methodology for therapeutic planning, promoting the standardisation of procedures without losing the necessary clinical personalisation.
The protocols constitute support tools and should always be adapted to professional judgement and the individual characteristics of each patient.
They include specific programmes for:
✔ oily skin;
✔ acne-prone skin;
✔ oil control;
✔ comedones;
✔ enlarged pores;
✔ superficial post-acne scars;
✔ superficial post-inflammatory hyperpigmentation;
✔ superficial freckles and lentigines;
✔ photodamage;
✔ optimisation of skin texture;
✔ Skin Quality;
✔ combined protocols.
________________________________________
THERAPDERMA SKINCARE™
Professional cosmetics to support each treatment
The TherapDerma Skincare™ line has been developed to complement in-clinic procedures through home-care programmes adapted to different skin needs.
The collection includes professional solutions designed to support treatment progression and promote continuity of care between sessions.
Its main categories include:
✔ professional cleansing;
✔ balanced hydration;
✔ skin barrier repair;
✔ soothing active ingredients;
✔ oil control;
✔ care for acne-prone skin;
✔ antioxidants;
✔ pigmentation control;
✔ photoprotection;
✔ maintenance of Skin Quality.
Each home-care programme should be individualised according to the characteristics, tolerance, recovery phase and objectives of each patient.
After a procedure with Salicylic Peel 25%, the home-care routine should prioritise skin barrier repair, hydration, skin comfort and photoprotection before reintroducing potentially irritating active ingredients.
________________________________________
THERAPDERMA PROFESSIONAL EDUCATION™
Scientific training for professionals
Continuous professional development is one of the pillars of modern aesthetic medicine.
Through TherapDerma Professional Education™, professionals have access to training programmes designed to expand clinical knowledge and remain up to date with the scientific development of the sector.
Training activities include, among others:
✔ specialised courses;
✔ clinical masterclasses;
✔ practical workshops;
✔ treatment protocols;
✔ clinical cases;
✔ scientific updates;
✔ training in chemical peels;
✔ selection between different acids and concentrations;
✔ protocols for oily and acne-prone skin;
✔ training in pigmentation irregularities and photodamage;
✔ prevention and management of undesirable responses;
✔ training in new technologies and procedures.
Our objective is to provide tools that contribute to professional development and clinical practice based on knowledge and the available evidence.
________________________________________
THERAPDERMA CLINICAL DECISION GUIDE™
Diagnosis and therapeutic selection
The TherapDerma Clinical Decision Guide™ is a quick-reference tool designed to facilitate selection of the most appropriate treatment according to the patient’s clinical characteristics.
It helps guide decision-making by considering aspects such as:
✔ skin type;
✔ degree of oiliness;
✔ presence of comedones;
✔ level of inflammation;
✔ condition of the skin barrier;
✔ phototype;
✔ pigmentary predisposition;
✔ texture irregularities;
✔ signs of photodamage;
✔ Skin Quality;
✔ therapeutic objectives;
✔ required level of intensity;
✔ integration with other procedures.
Its purpose is to facilitate more organised clinical practice that is consistent with the individual diagnosis.
________________________________________
THERAPDERMA CLINICAL ECOSYSTEM™
An ecosystem focused on clinical practice
All resources developed by TherapDerma form part of the same working philosophy, in which each tool complements the others and contributes to a comprehensive view of treatment.
TherapDerma Clinical Ecosystem
Clinical assessment

Professional diagnosis

Assessment of skin barrier function, phototype and risk factors

Therapeutic planning

Selection of the appropriate peel and concentration

Professional procedure

Physiological recovery

Clinical reassessment

Complementary treatments

Home care

Clinical follow-up

Personalised maintenance programme
This pathway represents a guiding model for clinical planning and should always be adapted to professional judgement and the specific needs of each patient.
________________________________________
RECOMMENDED RESOURCES
To expand the information and explore the different TherapDerma programmes in greater depth, we recommend consulting:
✔ TherapDerma™ Complete Peeling Catalogue
✔ Salicylic Peel Clinical Guide™
✔ TherapDerma Mesotherapy Collection™
✔ TherapDerma™ Clinical Protocol Manual
✔ TherapDerma Clinical Decision Guide™
✔ TherapDerma Professional Education™
✔ TherapDerma Business Intelligence™
✔ Clinical Combinations Guide
✔ TherapDerma™ Professional Cosmetics Guide
✔ TherapDerma™ Skin Quality Manual
✔ Photoprotection and Post-Peel Recovery Guide
✔ Complication Prevention and Management Manual
Each of these resources has been developed to provide practical information and facilitate the planning of personalised treatments within professional aesthetic medicine.
________________________________________
DISCOVER MORE SCIENTIFIC CONTENT
Professional development requires continuous training and permanent access to updated information.
For this reason, TherapDerma provides professionals with a continuously expanding scientific library that includes:
✔ clinical guides;
✔ professional manuals;
✔ complete protocols;
✔ decision-making algorithms;
✔ training videos;
✔ international masterclasses;
✔ reviewed clinical cases;
✔ scientific documentation;
✔ online training.
All these resources form part of TherapDerma’s commitment to aesthetic medicine based on scientific knowledge and clinical excellence.
________________________________________
THERAPDERMA AUDIOVISUAL CONTENT
Learn from our specialists
In addition to written documentation, TherapDerma develops audiovisual content designed to facilitate practical learning and scientific updating.
Professionals can access:
✔ TherapDerma Masterclasses;
✔ Clinical Series;
✔ clinical demonstrations;
✔ step-by-step protocols;
✔ interviews with specialists;
✔ scientific presentations;
✔ scientific webinars;
✔ therapeutic developments;
✔ product and technology updates.
This content makes it possible to complement theoretical training with practical examples applicable to daily clinical practice.
________________________________________
THERAPDERMA PHILOSOPHY
Much more than a chemical peel
At TherapDerma, we believe that an isolated procedure rarely constitutes the complete answer to a clinical need.
The best outcomes are achieved when diagnosis, therapeutic planning, scientific training, procedure selection, recovery and clinical follow-up form part of the same strategy.
For this reason, Salicylic Peel 25% does not merely represent a higher-concentration professional chemical peel, but a clinical tool integrated into the TherapDerma Clinical Ecosystem™, designed to develop personalised, progressive protocols based on scientific criteria.
Its true value lies in correctly selecting the patient, defining a precise clinical objective, controlling the intensity of the procedure and adapting each phase to the individual biological progression.
________________________________________
THERAPDERMA CONCLUSION
Scientific knowledge forms the basis of responsible clinical practice.
For this reason, Salicylic Peel 25% is not presented as an isolated procedure, but as part of the TherapDerma Clinical Ecosystem™, a professional environment that integrates scientific resources, continuing education, clinical protocols, technologies and complementary solutions to support the professional’s daily activity.
Through the TherapDerma Clinical Ecosystem™, we provide a collection of tools designed to facilitate therapeutic planning, promote scientific updating and contribute to the development of personalised, coherent and evidence-based aesthetic medicine.
Our commitment is to support professionals beyond the procedure by providing solutions that contribute to the continuous development of clinical knowledge and to personalised, responsible aesthetic medicine focused on progressive, reproducible results that respect skin physiology.

Therapderma Professional Academy™

Where knowledge is transformed into clinical excellence
Aesthetic medicine is constantly evolving. New scientific knowledge, technologies and procedures make continuous professional development essential in order to provide clinical practice that is increasingly evidence-based and adapted to patients’ needs.
With this vision, TherapDerma Professional Academy™ was created: an international training platform designed to support doctors, nurses, pharmacists, dentists, aestheticians and other professionals connected with aesthetic medicine, always within the legal and professional scope applicable in each country.
More than transmitting information, our mission is to help professionals develop clinical judgement, strengthen their analytical capacity and transform scientific knowledge into responsible therapeutic decisions.
Within this context, training in Salicylic Peel 25% is not limited to explaining how to apply a higher-concentration chemical peel. Its objective is to teach professionals to understand the physiology of oily skin, the behaviour of the pilosebaceous environment, epidermal renewal, rigorous patient selection and the integration of the procedure into a personalised therapeutic strategy.
________________________________________
OUR MISSION
Training professionals, not merely teaching procedures
At TherapDerma, we believe that true professional excellence does not depend solely on knowing a product or mastering a technique.
Above all, it depends on the ability to interpret scientific information, analyse each clinical situation and select the most appropriate strategy for every patient.
For this reason, our Academy has been developed to promote training based on critical thinking, continuous learning and professional development.
Our purpose is to help professionals to:
✔ understand the scientific foundations of aesthetic medicine;
✔ develop a broader clinical perspective;
✔ strengthen professional reasoning;
✔ make evidence-based decisions;
✔ correctly interpret the biological response of the skin;
✔ integrate knowledge into daily practice;
✔ distinguish between indication, precaution and contraindication;
✔ correctly select between different acids and concentrations;
✔ build personalised and clinically coherent protocols.
________________________________________
OUR EDUCATIONAL MODEL
Learning to think clinically
Training acquires genuine value when it enables professionals to interpret clinical reality more effectively and make decisions with greater confidence and judgement.
For this reason, the methodology of TherapDerma Professional Academy™ is based on a continuous learning process that promotes long-term professional development.
Our learning philosophy
Learn

Understand

Analyse

Diagnose

Decide

Apply

Evaluate

Reassess

Continue learning
This model transforms training into a dynamic process of continuous improvement, in which every new piece of knowledge contributes to professional growth and to more reflective, organised and responsible clinical practice.
________________________________________
TRAINING AREAS
Multidisciplinary knowledge for modern aesthetic medicine
The programmes developed by TherapDerma Professional Academy™ cover different areas related to professional practice, providing a comprehensive view of aesthetic medicine.
The main training areas include:
✔ professional chemical peels;
✔ scientific foundations of AHAs, BHAs, PHAs and other acids;
✔ clinical assessment of oily, acne-prone and photoaged skin;
✔ patient selection;
✔ selection between different concentrations;
✔ sebum regulation;
✔ protocols for comedones and enlarged pores;
✔ cosmetic management of acne-prone skin;
✔ superficial post-acne scars;
✔ superficial post-inflammatory hyperpigmentation;
✔ freckles, lentigines and photodamage;
✔ mesotherapy;
✔ biostimulation;
✔ PDRN;
✔ medical-aesthetic technologies;
✔ Skin Quality;
✔ professional cosmetics;
✔ clinical protocols;
✔ clinical cases;
✔ clinical documentation;
✔ patient communication;
✔ expectation management;
✔ prevention and management of adverse reactions;
✔ scientific updates.
Each programme has been designed to complement the professional’s experience and promote progressive, structured learning adapted to new developments within the sector.
________________________________________
SPECIFIC TRAINING IN SALICYLIC PEEL 25%
Understanding the procedure before applying it
Training in Salicylic Peel 25% is designed to provide professionals with a complete understanding of the product, its clinical behaviour and its integration into personalised higher-intensity superficial exfoliation protocols.
Training content may include:
✔ physicochemical characteristics of Salicylic Acid;
✔ lipophilic nature and affinity for sebum;
✔ action on the stratum corneum and pilosebaceous environment;
✔ differences between BHAs and AHAs;
✔ relationship between concentration, pH, pKa and skin response;
✔ clinical differences between Salicylic Peel 15% and Salicylic Peel 25%;
✔ professional indications;
✔ specific contraindications;
✔ allergy to aspirin and salicylates;
✔ assessment of phototype and pigmentary risk;
✔ assessment of skin barrier function;
✔ skin preparation;
✔ application technique;
✔ control of the amount and number of layers;
✔ control of contact time;
✔ clinical observation during the session;
✔ mandatory neutralisation;
✔ post-treatment care;
✔ session planning;
✔ professional and home photoprotection;
✔ integration with mesotherapy, PDRN, depigmentation protocols, LED therapy and home-care cosmetics;
✔ documentation and monitoring of clinical progression.
The objective is not simply to teach a technical sequence, but to help professionals understand why each decision is made during treatment.
________________________________________
TRAINING FORMATS
Training adapted to different professional profiles
Every professional has different needs, objectives and learning rhythms.
For this reason, TherapDerma Professional Academy™ develops programmes in different formats, allowing flexible access to knowledge adapted to each stage of professional development.
Training formats may include:
✔ face-to-face training;
✔ online training;
✔ scientific webinars;
✔ practical workshops;
✔ specialised masterclasses;
✔ congresses and professional meetings;
✔ clinical case analysis;
✔ protocol demonstrations;
✔ question-and-answer sessions;
✔ scientific update programmes;
✔ product-specific training;
✔ advanced therapeutic integration programmes.
All programmes share the same objective: to promote continuous, practical training aligned with the evolution of aesthetic medicine.
________________________________________
CLINICAL CASE-BASED LEARNING
From theory to decision-making
Clinical case analysis makes it possible to transform scientific knowledge into a tool applicable to daily practice.
Within training on Salicylic Peel 25%, cases may analyse variables such as:
✔ skin type;
✔ degree of oiliness;
✔ presence of comedones;
✔ level of inflammation;
✔ integrity of the skin barrier;
✔ phototype;
✔ predisposition to post-inflammatory hyperpigmentation;
✔ presence of photodamage;
✔ characteristics of pigmentary irregularities;
✔ superficial post-acne scars;
✔ previous medical or aesthetic treatments;
✔ home-care routine;
✔ recent or anticipated sun exposure;
✔ response observed between sessions;
✔ the need to modify, space out or discontinue the protocol.
This approach makes it possible to understand that the same formulation may require different strategies according to the biological and clinical characteristics of each patient.
________________________________________
WHAT MAKES THERAPDERMA PROFESSIONAL ACADEMY™ DIFFERENT?
More than teaching procedures, we develop clinical judgement
At TherapDerma, we understand that learning a technique represents only one part of professional development.
Our educational philosophy seeks to train professionals capable of interpreting scientific information, analysing each clinical situation and making evidence-based decisions.
Our way of teaching
We do not teach products alone.
We teach professionals to understand their scientific basis.
We do not teach concentrations alone.
We teach professionals to interpret the formulation as a whole.
We do not teach that a higher concentration is automatically better.
We teach professionals to select the correct concentration for each patient.
We do not teach protocols alone.
We teach professionals to build therapeutic strategies.
We do not teach techniques alone.
We teach professionals to observe the biological response.
We do not teach indications alone.
We also teach professionals to recognise precautions and contraindications.
We do not teach treatments alone.
We teach professionals to individualise every decision.
We do not teach innovation alone.
We teach professionals to interpret scientific evidence and apply it responsibly.
We believe that knowledge acquires true value when it helps professionals make better decisions for the benefit of each patient.
________________________________________
CLINICAL COMPETENCIES WE PROMOTE
Knowledge applied to professional practice
TherapDerma training seeks to promote the development of competencies that enable professionals to act with greater judgement, precision and safety.
These include:
✔ performing a structured clinical assessment;
✔ identifying the priority needs of the skin;
✔ correctly selecting the peel and concentration;
✔ assessing skin barrier function and phototype;
✔ interpreting the skin response during the procedure;
✔ adapting the amount, number of layers and contact time;
✔ recognising signs of irritation or an excessive response;
✔ deciding when to continue, modify, neutralise or end a session;
✔ planning intervals between procedures;
✔ preventing cumulative sensitisation;
✔ integrating home care and photoprotection;
✔ documenting clinical progression;
✔ communicating realistic expectations to the patient;
✔ maintaining practice based on continuous reassessment.
These competencies make it possible to transform technical knowledge into an organised clinical methodology.
________________________________________
TRAINING IN CLINICAL SAFETY
Prevention also forms part of treatment
Safety is one of the fundamental pillars of all TherapDerma Professional Academy™ programmes.
Training in chemical peels includes content intended to:
✔ identify contraindications;
✔ recognise impairment of the skin barrier;
✔ assess compatibility with previous treatments;
✔ detect a history of allergy to aspirin or salicylates;
✔ assess the risk of post-inflammatory hyperpigmentation;
✔ identify pigmented or keratotic lesions requiring medical assessment;
✔ prevent over-exfoliation;
✔ avoid potentially irritating combinations;
✔ adequately control contact time;
✔ perform neutralisation correctly;
✔ respond to an unexpected reaction;
✔ correctly guide post-treatment care;
✔ establish criteria for medical referral where necessary.
Safe practice begins before application and continues throughout every phase of clinical follow-up.
________________________________________
TRAINING IN COMBINED PROTOCOLS
Integrating procedures with clinical judgement
Modern aesthetic medicine makes it possible to combine different tools, but the accumulation of procedures does not automatically guarantee better results.
For this reason, the Academy teaches professionals to integrate Salicylic Peel 25% into sequential strategies that may include:
✔ personalised mesotherapy;
✔ sebum-regulating protocols;
✔ depigmentation protocols;
✔ PDRN;
✔ biostimulation;
✔ blue LED therapy;
✔ red LED therapy;
✔ compatible medical-aesthetic technologies;
✔ professional home-care cosmetics;
✔ skin barrier recovery programmes;
✔ maintenance programmes.
Each combination should address a specific clinical objective and respect recovery of the skin barrier before the next phase is introduced.
________________________________________
TRAINING AND CLINICAL DOCUMENTATION
Organised practice also requires accurate records
Correct documentation of each procedure facilitates follow-up, reproducibility and continuity of care.
Training programmes promote the recording of:
✔ initial diagnosis;
✔ treatment indication;
✔ relevant history;
✔ phototype and pigmentary risk;
✔ initial condition of the skin barrier;
✔ products used;
✔ treatment areas;
✔ amount applied;
✔ number of layers where appropriate;
✔ contact time;
✔ immediate skin response;
✔ neutralisation and removal;
✔ post-treatment care;
✔ progression between sessions;
✔ protocol modifications;
✔ observed results;
✔ clinical decisions adopted.
Documentation is a fundamental tool for assessing progression and progressively improving the quality of professional practice.
________________________________________
THERAPDERMA PROFESSIONAL COMMUNITY
Learn, share and evolve
TherapDerma Professional Academy™ also promotes the development of an international community of professionals committed to continuous training and responsible clinical practice.
This environment makes it possible to:
✔ share professional experiences;
✔ analyse clinical cases;
✔ exchange treatment criteria;
✔ learn about new protocols;
✔ update knowledge;
✔ discover new technologies;
✔ participate in international masterclasses;
✔ maintain an ongoing relationship with the TherapDerma ecosystem.
Learning is strengthened when knowledge is shared within a professional community focused on excellence.
________________________________________
THERAPDERMA PHILOSOPHY
Knowledge as the driving force behind professional excellence
Innovation is constantly evolving.
Products change.
Technologies advance.
Trends transform.
However, scientific knowledge and clinical reasoning remain the foundation upon which solid professional practice is built.
For this reason, TherapDerma Professional Academy™ promotes a culture of lifelong learning, in which every training programme represents an opportunity to expand knowledge, refine skills and evolve professionally.
Our commitment is to support professionals throughout their careers by providing tools that promote increasingly safe, organised, personalised and evidence-based clinical practice.
________________________________________
THERAPDERMA PROFESSIONAL ACADEMY™ WITHIN THE CLINICAL ECOSYSTEM
Training is not an activity independent of treatment.
It forms part of a professional model in which every element is connected:
Scientific knowledge

Professional training

Clinical assessment

Individualised diagnosis

Selection of the acid and concentration

Therapeutic planning

Professional application

Recovery and clinical follow-up

Analysis of results

Continuous updating
This process enables clinical practice to evolve continuously and adapt to the real needs of each patient.
________________________________________
THERAPDERMA CONCLUSION
TherapDerma Professional Academy™ is one of the pillars of the TherapDerma Clinical Ecosystem™, integrating scientific training, professional development and continuous updating within the same working philosophy.
In the case of Salicylic Peel 25%, training makes it possible to understand that treatment success does not depend solely on applying a higher concentration, but on correctly assessing the skin, identifying an appropriate indication, interpreting the biological response and individually planning every phase of the protocol.
We believe that clinical excellence begins long before the first procedure. It begins with a professional who maintains an attitude of continuous learning, interprets scientific evidence critically and adapts decisions to the individual needs of each patient.
Beyond delivering training programmes, our mission is to contribute to the growth of a community of professionals committed to ethical, personalised and knowledge-based aesthetic medicine.
Because the best treatment begins long before the first procedure.
It begins with a professional prepared to make the right decision.

Therapderma Clinical Decision System™

Transforming scientific knowledge into clinical decisions
Modern aesthetic medicine requires far more than simply knowing the characteristics of a product.
Every patient presents different biological needs, clinical manifestations, expectations and recovery capacities. For this reason, treatment selection should not be based solely on personal experience or on the automatic application of standardised protocols.
The TherapDerma Clinical Decision System™ (TCDS™) has been developed as a structured framework for clinical reasoning designed to help professionals transform the information obtained during assessment into individualised, scientifically based decisions.
Its objective is to facilitate:
✔ clinical assessment;
✔ identification of indications and contraindications;
✔ definition of therapeutic objectives;
✔ selection of the most appropriate procedure;
✔ personalised treatment planning;
✔ clinical observation and reassessment;
✔ clinical documentation;
✔ continuity of patient care.
The system does not replace professional judgement, the applicable scope of professional practice or the official technical instructions for each product.
________________________________________
STEP 1
CLINICAL ASSESSMENT AND DIAGNOSIS
Every protocol begins with a comprehensive patient assessment.
Before selecting a chemical peel, the professional should identify the skin’s needs and the factors that may influence its biological response.
The assessment may include:
✔ reason for consultation;
✔ patient expectations;
✔ medical and dermatological history;
✔ current medication;
✔ known allergies;
✔ history of allergy to aspirin or other salicylates;
✔ previous medical and aesthetic treatments;
✔ skin type and functional characteristics;
✔ sebaceous activity;
✔ presence of excessive shine;
✔ condition of the stratum corneum;
✔ integrity of the skin barrier;
✔ skin sensitivity and reactivity;
✔ phototype;
✔ presence of comedones;
✔ appearance of the pores;
✔ type and severity of acne;
✔ presence of photodamage;
✔ superficial post-inflammatory hyperpigmentation;
✔ superficial freckles or lentigines;
✔ superficial post-acne marks;
✔ presence of lesions, irritation, infection or inflammation;
✔ home skincare routine;
✔ lifestyle and sun exposure;
✔ ability to comply with post-treatment care.
A thorough assessment makes it possible to recognise indications, detect possible contraindications and establish a treatment plan adapted to the characteristics and needs of each patient.
________________________________________
STEP 2
IDENTIFICATION OF THE CLINICAL OBJECTIVE
Following the initial assessment, the main objective of the protocol should be clearly defined.
For patients who may be candidates for Salicylic Peel 25%, the objectives may include:
✔ progressively regulating excess sebum;
✔ reducing skin shine;
✔ promoting pore purification;
✔ reducing follicular congestion;
✔ improving the appearance of comedones;
✔ supporting protocols for acne-prone skin;
✔ progressively refining superficial skin texture;
✔ promoting greater visual skin uniformity;
✔ improving the appearance of superficial post-acne marks;
✔ improving certain superficial tone irregularities;
✔ promoting the progressive improvement of superficial photodamage;
✔ progressively optimising Skin Quality;
✔ sequentially preparing the skin for other procedures where clinically indicated.
Defining the objective beforehand makes it possible to select the most appropriate procedure, establish follow-up criteria and communicate realistic expectations to the patient.
________________________________________
STEP 3
PEEL SELECTION
The professional should determine whether Salicylic Peel 25% represents the most appropriate option for the assessed patient.
The decision should take into account:
✔ sebaceous activity;
✔ presence of comedones;
✔ degree of follicular congestion;
✔ appearance of the pores;
✔ type and severity of acne;
✔ presence of active inflammation;
✔ skin sensitivity and reactivity;
✔ integrity of the skin barrier;
✔ thickness and functional condition of the stratum corneum;
✔ presence of irregular texture;
✔ superficial tone irregularities;
✔ photodamage;
✔ superficial freckles or lentigines;
✔ superficial post-inflammatory hyperpigmentation;
✔ post-acne marks;
✔ phototype;
✔ risk of post-inflammatory hyperpigmentation;
✔ previous experience with chemical peels;
✔ response to previous treatments;
✔ recovery capacity;
✔ established therapeutic objectives;
✔ ability to comply with post-treatment care.
Salicylic Peel 25% may be considered when the objective is to promote higher-intensity superficial exfoliation, progressively control oiliness and improve the appearance of correctly selected oily, congested, photoaged or acne-prone skin.
The final indication should always be established through an individualised clinical assessment.
________________________________________
STEP 4
EXCLUSION OF CONTRAINDICATIONS
Before planning the procedure, the professional should confirm that no circumstances exist that could compromise safety.
The following should be specifically excluded:
✔ pregnancy or breastfeeding;
✔ allergy to aspirin;
✔ hypersensitivity to Salicylic Acid or other salicylates;
✔ hypersensitivity to any component of the formulation;
✔ active skin infections;
✔ active herpes;
✔ wounds, abrasions or erosions;
✔ sunburn;
✔ active dermatitis or eczema;
✔ active psoriasis in the treatment area;
✔ inflammatory rosacea;
✔ extremely reactive skin;
✔ significant impairment of the skin barrier;
✔ recent incompatible medical or aesthetic procedures;
✔ recent use of retinoids or other keratolytic agents;
✔ inability to comply with post-treatment care.
Where any clinical doubt exists, the procedure should be postponed, modified or ruled out until an appropriate assessment has been carried out.
________________________________________
STEP 5
PROTOCOL PERSONALISATION
The concentration of the peel represents only one of the factors influencing the skin response.
The protocol should be adapted by considering:
✔ prior skin preparation;
✔ temporary discontinuation of potentially irritating active ingredients;
✔ cleansing and degreasing where indicated;
✔ protection of sensitive areas;
✔ amount of product;
✔ number of layers where included in the protocol;
✔ extent of the treatment area;
✔ contact time;
✔ application technique and sequence;
✔ clinical observation during the procedure;
✔ neutralisation according to the official technical instructions;
✔ complete removal of the product;
✔ immediate post-treatment care;
✔ home-care cosmetics;
✔ recovery intervals;
✔ session frequency;
✔ integration with other procedures;
✔ response observed during previous sessions.
Personalisation makes it possible to adapt the procedure to the functional characteristics of the skin, improve predictability and reduce avoidable risks.
________________________________________
STEP 6
PROFESSIONAL APPLICATION
The application should follow the official technical protocol for Salicylic Peel 25% TherapDerma.
During the procedure, the professional should monitor:
✔ appropriate preparation of the treatment area;
✔ protection of the eyes, lips, mucous membranes and sensitive areas;
✔ amount and distribution of the product;
✔ number of layers;
✔ uniformity of application;
✔ contact time;
✔ the comfort reported by the patient;
✔ the appearance of erythema;
✔ sensations of warmth, stinging or burning;
✔ differences in response between different regions;
✔ the need to end the procedure before the originally planned contact time;
✔ mandatory neutralisation;
✔ complete removal of the product.
Patient safety and the observed skin response should always take precedence over strict adherence to a pre-established contact time.
________________________________________
STEP 7
RECOVERY AND INTEGRATION OF OTHER PROCEDURES
After the peel, sufficient time should be allowed for skin recovery.
Before introducing another procedure, the professional should verify:
✔ recovery of the skin barrier;
✔ absence of persistent irritation;
✔ resolution of significant erythema;
✔ resolution of significant desquamation;
✔ absence of open lesions;
✔ absence of unexpected reactions;
✔ compliance with home-care recommendations;
✔ clinical suitability of the next intervention.
Where indicated, the following may subsequently be incorporated:
✔ personalised mesotherapy;
✔ sebum-regulating protocols;
✔ depigmentation protocols;
✔ professional PDRN solutions;
✔ biostimulation;
✔ blue LED therapy;
✔ red LED therapy;
✔ compatible medical-aesthetic technologies;
✔ radiofrequency;
✔ professional home-care cosmetics.
These combinations should not be performed automatically or necessarily during the same session.
The sequence and intervals should always respect the characteristics of each procedure, skin barrier recovery and the patient’s individual biological response.
________________________________________
STEP 8
FOLLOW-UP AND CLINICAL REASSESSMENT
Decision-making continues after every session.
Follow-up makes it possible to assess:
✔ recovery of the skin barrier;
✔ tolerance to the procedure;
✔ occurrence of unexpected reactions;
✔ progression of oiliness;
✔ reduction of skin shine;
✔ evolution of comedones;
✔ appearance of the pores;
✔ progression of congestion;
✔ changes in superficial skin texture;
✔ progression of post-acne marks;
✔ progression of superficial pigmentary irregularities;
✔ progression of photodamage;
✔ visual skin uniformity;
✔ progression of Skin Quality;
✔ compliance with home care;
✔ patient perception and satisfaction;
✔ the need to continue, modify, postpone or discontinue the protocol.
Each review provides valuable information for adapting the subsequent stages of treatment.
Continuation of the programme should never be considered automatic.
________________________________________
STEP 9
CLINICAL DOCUMENTATION
Every procedure should be appropriately documented.
The record may include:
✔ initial assessment;
✔ professional diagnosis;
✔ clinical indication;
✔ treatment objectives;
✔ contraindications excluded;
✔ aspirin and salicylate allergy excluded;
✔ informed consent;
✔ product and concentration used;
✔ batch number and expiry date where applicable;
✔ treatment area;
✔ skin preparation;
✔ number of layers;
✔ approximate amount applied;
✔ contact time;
✔ observed response;
✔ timing and method of neutralisation;
✔ complete removal of the product;
✔ recommended post-treatment care;
✔ incidents;
✔ progression reported by the patient;
✔ photographic records where authorised;
✔ follow-up date;
✔ protocol modifications.
Documentation promotes traceability, facilitates comparison between sessions and contributes to continuity of patient care.
________________________________________
THERAPDERMA™ ALGORITHM
From assessment to clinical decision
Clinical assessment

Assessment of sebaceous activity, pores, comedones, photodamage, pigmentary irregularities and skin barrier function

Identification of indications and contraindications

Exclusion of allergy to aspirin and salicylates

Definition of the clinical objective

Selection of the peel and concentration

Protocol personalisation

Controlled professional application

Mandatory neutralisation

Complete removal and post-treatment care

Recovery and reassessment

Possible integration of complementary procedures

Follow-up and documentation

Individualised maintenance
This algorithm provides a guiding framework within the TherapDerma Clinical Decision System™.
It does not represent a universal protocol.
Each stage should be adapted to the diagnosis, the professional’s scope of practice, the official product instructions and the individual clinical progression.
________________________________________
CLINICAL DECISION TREE
Can Salicylic Peel 25% be considered?
1. Is there oily skin, excess oiliness, comedones, visible pores, superficial photodamage, superficial pigmentary irregularities or acne-prone skin?
NO
→ Consider another TherapDerma solution better suited to the clinical objective.
YES

2. Is the condition predominantly superficial and compatible with higher-intensity BHA action?
NO
→ Reassess the diagnosis and consider another strategy.
YES

3. Is the skin barrier intact?
NO
→ Prioritise skin recovery and postpone the peel.
YES

4. Is there an allergy to aspirin, Salicylic Acid or other salicylates?
YES
→ Do not perform Salicylic Peel 25%.
NO

5. Are there active infections, significant inflammation, wounds or active dermatoses?
YES
→ Postpone or rule out the procedure and consider medical referral where appropriate.
NO

6. Can the patient comply with photoprotection and home-care recommendations?
NO
→ Reconsider the timing of the procedure.
YES

7. Does Salicylic Peel 25% meet the defined clinical objective?
YES
→ Personalise and perform the professional protocol.
NO
→ Select another formulation, concentration or therapeutic strategy.
________________________________________
CRITERIA FOR CHOOSING BETWEEN SALICYLIC PEEL 15% AND 25%
The choice between the two concentrations should not be based on automatic progression.
Salicylic Peel 15% may be considered when the objective is to:
✔ achieve progressive superficial exfoliation;
✔ control excess sebum;
✔ improve the appearance of the pores;
✔ promote reduction of comedones;
✔ develop initial or maintenance programmes;
✔ prioritise a high level of clinical control;
✔ initially assess tolerance to Salicylic Acid.
Salicylic Peel 25% may be considered when the objective is to:
✔ achieve higher-intensity superficial exfoliation;
✔ address more pronounced superficial irregularities;
✔ improve the appearance of superficial post-acne scars;
✔ treat superficial post-inflammatory hyperpigmentation;
✔ improve the appearance of superficial photodamage;
✔ address superficial freckles or lentigines where clinically indicated;
✔ intervene within advanced protocols under professional judgement.
Progression from one concentration to another should always be justified by:
✔ diagnosis;
✔ observed progression;
✔ tolerance;
✔ recovery of the skin barrier;
✔ response to previous sessions;
✔ therapeutic objective.
________________________________________
BENEFITS OF THE THERAPDERMA CLINICAL DECISION SYSTEM™
The use of a structured model may help professionals to:
✔ organise clinical assessment;
✔ recognise indications and contraindications;
✔ identify allergies and risk factors;
✔ define realistic therapeutic objectives;
✔ select procedures on a stronger scientific basis;
✔ individualise each protocol;
✔ improve observation during treatment;
✔ correctly integrate neutralisation and post-treatment care;
✔ promote safer clinical practice;
✔ improve communication with the patient;
✔ facilitate continuity of care;
✔ reduce automatic or insufficiently justified decisions;
✔ document and reassess every stage;
✔ adapt the programme according to the observed clinical response;
✔ rationally select between Salicylic Peel 15% and Salicylic Peel 25%.
Organised knowledge promotes decisions that are more consistent with the biological characteristics of each patient.
________________________________________
TCDS™ PHILOSOPHY
At TherapDerma, we understand that no product represents the appropriate solution for every patient.
The value of clinical reasoning lies in understanding:
✔ when a treatment may be used;
✔ when it should not be used;
✔ in which patient;
✔ for what objective;
✔ with which formulation and concentration;
✔ using which technique;
✔ for how long;
✔ within which therapeutic sequence;
✔ with which post-treatment care;
✔ when it should be modified or discontinued.
The TherapDerma Clinical Decision System™ does not replace professional judgement, training, responsibility or the applicable legal framework.
It provides a methodology based on:
✔ assessment;
✔ diagnosis;
✔ selection;
✔ personalisation;
✔ clinical observation;
✔ neutralisation;
✔ recovery;
✔ follow-up;
✔ documentation;
✔ reassessment.
Every decision should be based on skin physiology and functional status, and not solely on the technical or commercial characteristics of the product.
________________________________________
TCDS™ QUICK CHECK
Before performing Salicylic Peel 25%, confirm:
☐ A compatible clinical indication exists.
☐ The therapeutic objective has been clearly defined.
☐ The skin presents sebaceous activity, congestion, comedones, photodamage or superficial irregularities compatible with the product.
☐ The skin barrier is intact.
☐ There are no open lesions or active infections.
☐ There are no active inflammatory dermatoses.
☐ Allergy to aspirin and other salicylates has been excluded.
☐ Recent medical and aesthetic treatments have been reviewed.
☐ Pigmentary risk has been assessed.
☐ The appropriate concentration has been selected.
☐ The protocol has been individualised.
☐ The patient understands the expectations and post-treatment care.
☐ Clinical follow-up can be provided.
________________________________________
THERAPDERMA CONCLUSION
The TherapDerma Clinical Decision System™ provides a structured framework to support assessment, treatment selection and planning in aesthetic medicine.
Rather than offering rigid protocols, it organises clinical reasoning and facilitates the transformation of scientific knowledge into individualised, justified and evidence-based decisions.
Integrated within the TherapDerma Clinical Ecosystem™, it enables Salicylic Peel 25% to be incorporated into a strategy that includes:
✔ diagnosis;
✔ appropriate patient selection;
✔ exclusion of allergy to aspirin and salicylates;
✔ definition of clinical objectives;
✔ protocol personalisation;
✔ controlled application;
✔ mandatory neutralisation;
✔ skin recovery;
✔ follow-up;
✔ documentation;
✔ continuity of patient care.
This approach may contribute to the progressive regulation of excess sebum, purification of the pilosebaceous environment, improvement of the appearance of comedones, pores, certain superficial tone irregularities, photodamage and superficial post-acne scars, progressively optimising Skin Quality where there is an appropriate professional indication.
Every decision, every procedure and every stage should be adapted to the individual needs, tolerance, recovery and biological progression of each patient.

More Informations

Aesthetic Professional Account

Get access to prices, online ordering and administration protocols

Join Our Newsletter


Customer support
U.S.A.

900 Biscayne Blvd. office 501
Miami FL 33132
Phone: +1-786-546-8347 (also whatsapp)

Venezuela

Avenida: Manongo Cruce Con Calle Libra #

163-20. Urbanizacion Trigal Norte. Valencia – Estado – Carabobo.

Telefonos Oficina :(+58) 241.843.5596 | Celular:(+58) 414.422.8809

Portugal

Rua dos Lagares Del Rey, nº 21 C, 1º Esq
1700 268 Lisboa
Portugal

Telefones:
+351 910 645 779 (também Whatsapp)

+351 912 305 434 (também Whatsapp)