Gluconolactone is an active ingredient that gently treats the skin without affecting the deeper layers. The effect is very similar to that of AHAs (fruit acids like glycolic or lactic acid), but as a type of polyhydroxy acid, gluconolactone is more beneficial. As it contains five hydroxyl groups, it has more moisturizing properties compared to alpha hydroxy acid with only one hydroxyl group.
Because it is a larger molecule (with a three-dimensional molecule of 178 Da), gluconolactone penetrates the skin slowly, without burning it, as other chemical peels do with alternative active ingredients. That’s why non-irritating gluconolactone is perfect even for dry and hypersensitive skin. It also activates lipid synthesis in keratinocytes, providing moisture to the stratum corneum of the skin. Gluconolactone has the ability to transfer water molecules, playing a central role in skin hydration. As a chelating agent, gluconolactone has the ability to bind and remove free radicals from the body.
The oxidation process, caused by an overabundance of iron and the influence of ultraviolet rays, occurs in skin pigmentation, a typical sign of photoaging. Gluconolactone helps bind free iron ions, preventing the oxidation process and the consequences of ultraviolet radiation. Gluconolactone initiates processes that precede hyaluronic acid production in keratinocytes and fibroblasts, as well as matrix metalloproteinase and collagen synthesis.