Description
Malic Peel 15%
Progressive superficial epidermal renewal, skin revitalisation and improvement of skin texture and radiance within personalised professional protocols
Malic Peel 15% TherapDerma is a professional chemical peel formulated with 15% Malic Acid, belonging to the Alpha Hydroxy Acid (AHA) family. It has been developed to promote progressive superficial epidermal renewal in a clinically controlled manner that respects skin physiology, integrating into advanced aesthetic medicine protocols.
Malic Acid combines exfoliating and moisturising properties that promote the gradual reorganisation of the stratum corneum, helping to improve surface texture, enhance natural radiance and revitalise the appearance of the skin without compromising its physiological balance when applied under professional supervision.
Its use may contribute to optimising SKIN QUALITY, promoting greater visual tone uniformity, softening the appearance of fine expression lines and being incorporated into protocols intended for dull, dehydrated, photoaged skin or skin with superficial texture irregularities, while always respecting the individual biological response.
More than an isolated procedure, Malic Peel 15% forms part of the TherapDerma Clinical Ecosystem™, a methodology based on diagnosis, therapeutic planning, treatment personalisation and continuity of care.
What makes Malic Peel 15% different?
Not all chemical peels respond to the same clinical objective.
Each acid possesses its own physicochemical characteristics that determine its biological behaviour, its affinity for the skin and its role within personalised professional protocols.
Malic Peel 15% has been developed for professionals who wish to incorporate progressive epidermal renewal strategies aimed at revitalising the skin, improving its texture, restoring its natural radiance and promoting a more even and healthier skin appearance.
Its formulation combines the characteristic exfoliating action of Alpha Hydroxy Acids with the moisturising properties of Malic Acid, promoting gradual renewal compatible with programmes designed to optimise Skin Quality.
Integrated within sequential therapeutic planning, it enables the development of progressive treatments adapted to each patient’s clinical evolution, while respecting the biological timing of skin recovery.
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What is Malic Acid?
Malic Acid is an Alpha Hydroxy Acid (AHA) naturally present in fruits such as apples and pears. In aesthetic medicine, it is used to promote progressive superficial chemical exfoliation associated with an appropriate balance between epidermal renewal and hydration of the stratum corneum.
Its cosmetic profile facilitates the gradual removal of superficial corneocytes while helping to maintain skin flexibility, improve texture and promote a brighter and more revitalised appearance.
When incorporated into properly planned professional protocols, it may contribute to improving visual tone uniformity, softening the appearance of fine expression lines, promoting a more even skin appearance and supporting the physiological processes of epidermal renewal.
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When should Malic Peel 15% be selected?
Malic Peel 15% may be considered when the clinical assessment identifies the need to promote progressive superficial epidermal renewal aimed at improving overall skin quality, while maintaining a high level of safety and professional control.
It may be incorporated into personalised protocols intended for patients presenting:
• dull or devitalised skin;
• dehydrated skin;
• irregular surface texture;
• fine expression lines;
• early photoageing;
• superficial hyperpigmentation;
• appropriately selected normal, dry, combination or sensitive skin;
• revitalisation and Skin Quality programmes;
• protocols designed to enhance natural radiance;
• regular maintenance of skin quality.
The final indication should always be established following an individual clinical assessment.
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Positioning within the TherapDerma Clinical Ladder™
At TherapDerma, we understand that the concentration of a peel is a tool intended to adapt treatment to the specific needs of each patient and not an indicator of therapeutic superiority.
Each acid and each concentration correspond to different clinical objectives, specific skin profiles and distinct levels of action.
Malic Peel 15% occupies a position aimed at skin revitalisation and progressive epidermal renewal protocols designed to improve texture, enhance radiance and optimise Skin Quality.
Treatment progression will always depend on the diagnosis, the individual biological response, the recovery of the skin barrier function and the clinical reassessment carried out by the professional.
It may also be integrated sequentially with other TherapDerma solutions whenever therapeutic planning justifies it, always respecting the physiological intervals between procedures.
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TherapDerma Philosophy
At TherapDerma, we believe that the best clinical outcomes do not depend solely on the intensity of exfoliation.
They depend on understanding skin biology, establishing an accurate diagnosis and selecting the most appropriate therapeutic strategy for each patient.
Epidermal renewal only acquires real value when it forms part of rigorous clinical planning that respects the skin barrier function, the skin’s recovery capacity and the individual biological response.
For this reason, Malic Peel 15% is integrated within the TherapDerma Clinical Ecosystem™, a working model that combines chemical peels, mesotherapy, medical-aesthetic technologies and home care through personalised protocols based on clinical criteria.
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TherapDerma Conclusion
Malic Peel 15% is a clinical tool intended for professionals who wish to incorporate skin revitalisation protocols through progressive epidermal renewal, aimed at improving texture, enhancing natural radiance and optimising Skin Quality.
Its formulation may contribute to progressively improving SKIN QUALITY, promoting greater visual tone uniformity and supporting the physiological processes of epidermal renewal when the procedure is performed under professional supervision.
Its true value lies not only in the concentration of the active ingredient, but also in its ability to be integrated into structured therapeutic strategies based on diagnosis, clinical planning, periodic reassessment and continuity of care, enabling the development of personalised treatments that are consistent with skin physiology and with the specific needs of each patient.
Clinical Benefits
Progressive epidermal renewal, skin revitalisation and enhanced radiance within personalised professional protocols
Malic Peel 15% TherapDerma has been developed to promote progressive superficial epidermal renewal in a clinically controlled manner that respects skin physiology. It is intended for professionals wishing to incorporate personalised protocols aimed at revitalising the skin and optimising its Skin Quality.
Thanks to the properties of Malic Acid, this peel combines the characteristic exfoliating action of Alpha Hydroxy Acids (AHAs) with outstanding moisturising capacity, promoting the gradual reorganisation of the stratum corneum, refinement of skin texture and a brighter, more even and revitalised appearance.
When incorporated into an individualised clinical protocol, its benefits develop progressively while respecting the skin barrier function, the physiological mechanisms of skin renewal and each patient’s specific biological response.
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✨ Progressive Epidermal Renewal
What does it provide clinically?
The chemical exfoliation promoted by Malic Peel 15% encourages the gradual removal of superficial corneocytes, facilitating the reorganisation of the stratum corneum and supporting the physiological processes of epidermal renewal.
This mechanism contributes to optimising superficial skin quality, provided the procedure forms part of appropriate clinical planning.
Clinical benefits
✔ Supports progressive epidermal renewal.
✔ Contributes to improving surface texture.
✔ Promotes a more even skin appearance.
✔ Respects the physiological mechanisms of skin renewal.
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💧 Skin Hydration and Flexibility
What does it provide clinically?
Malic Acid possesses moisturising properties that help maintain hydration of the stratum corneum and promote more flexible and comfortable skin during skin renewal protocols.
Its use contributes to preserving the skin’s superficial balance and helps maintain a healthier appearance.
Clinical benefits
✔ Optimises superficial hydration.
✔ Contributes to improving skin flexibility.
✔ Helps maintain softer skin.
✔ Promotes skin comfort.
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🌿 Skin Revitalisation
What does it provide clinically?
Malic Peel 15% may be incorporated into professional protocols intended for dull, tired or devitalised skin, promoting a progressively fresher and healthier appearance.
Its action contributes to restoring natural radiance and progressively improving the overall appearance of the skin.
Clinical benefits
✔ Promotes skin revitalisation.
✔ Contributes to a healthier appearance.
✔ Helps restore natural radiance.
✔ Progressively optimises superficial skin quality.
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🌟 Improved Skin Tone Uniformity
What does it provide clinically?
The gradual renewal of the superficial layers of the epidermis promotes a more even skin tone and may contribute to the visible improvement of superficial pigmentation irregularities.
The progressive reorganisation of the skin surface helps achieve a visually more homogeneous complexion as treatment progresses.
Clinical benefits
✔ Promotes greater visual tone uniformity.
✔ May contribute to improving superficial hyperpigmentation.
✔ Promotes a more homogeneous skin appearance.
✔ Contributes to optimising superficial skin quality.
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🎯 Refinement of Skin Texture
What does it provide clinically?
The progressive reorganisation of the skin microrelief promotes a smoother, more flexible surface that is more pleasant to the touch, gradually improving the skin’s visual quality.
Clinical benefits
✔ Helps achieve a more even skin texture.
✔ Contributes to smoother skin.
✔ Progressively reduces the sensation of roughness.
✔ Promotes improved superficial skin quality.
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🌸 Renewed Radiance
What does it provide clinically?
The gradual removal of superficial cells helps create a more uniform reflection of light on the skin, providing a brighter, fresher and more revitalised appearance.
The clinical response continues to develop progressively as treatment sessions advance.
Clinical benefits
✔ Promotes enhanced radiance.
✔ Contributes to a revitalised appearance.
✔ Promotes a healthy-looking complexion.
✔ Improves the visual perception of skin vitality.
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🧬 Support for Skin Quality
What does it provide clinically?
Various studies suggest that Malic Acid may support physiological processes related to skin renewal and contribute to maintaining firmer, more flexible and younger-looking skin when incorporated into properly planned protocols.
Clinical benefits
✔ Promotes overall skin quality.
✔ Contributes to a firmer appearance.
✔ Helps visibly minimise fine lines.
✔ Integrates into professional Skin Quality protocols.
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📈 Progressive Clinical Evolution
The benefits associated with Malic Peel 15% form part of a progressive biological process and do not depend on a single session.
The clinical response develops as applications progress, respecting the physiological timing of epidermal renewal, the skin barrier function and the individual’s biological adaptation.
An accurate diagnosis, appropriate patient selection and personalised therapeutic planning make it possible to develop protocols consistent with the established clinical objectives.
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CLINICAL SUMMARY
Main Benefits of Malic Peel 15%
✔ Progressive epidermal renewal.
✔ Skin hydration and flexibility.
✔ Skin revitalisation.
✔ Improved visual tone uniformity.
✔ Refinement of surface texture.
✔ Renewed radiance.
✔ Support for skin quality.
✔ Progressive clinical evolution.
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THERAPDERMA CLINICAL CONCLUSION
The principal clinical value of Malic Peel 15% lies in combining progressive epidermal renewal with superficial hydration, skin revitalisation and gradual improvement of texture, radiance and Skin Quality.
Integrated within the TherapDerma Clinical Ecosystem™, it may form part of therapeutic strategies based on diagnosis, clinical planning and periodic reassessment, contributing to the development of personalised, progressive treatments that respect skin physiology and are aimed at achieving natural and clinically predictable results.
Why Choose Malic Peel 15%?
A professional option for skin revitalisation protocols, progressive epidermal renewal and overall improvement of skin quality
In professional aesthetic medicine, the choice of a chemical peel should not be based solely on the concentration of the acid, but on selecting the active ingredient best suited to the biological needs of each skin type.
Malic Peel 15% has been developed for professionals wishing to incorporate protocols aimed at promoting progressive epidermal renewal, revitalising the skin, enhancing its radiance, improving texture and optimising Skin Quality within personalised aesthetic medicine programmes.
Its formulation combines the characteristic exfoliating action of Alpha Hydroxy Acids with the moisturising properties of Malic Acid, promoting the physiological reorganisation of the stratum corneum while helping to maintain skin that is more flexible, comfortable and healthy-looking.
Rather than simply representing a specific concentration, Malic Peel 15% is a clinical tool intended for patients requiring progressive revitalisation, improved texture and restoration of natural radiance through protocols that respect skin physiology.
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WHEN MAY IT BE AN APPROPRIATE OPTION?
Malic Peel 15% may be considered when the professional identifies the need to promote progressive epidermal renewal combined with skin revitalisation and superficial hydration.
It may be incorporated into personalised protocols intended for:
✔ dull and devitalised skin;
✔ dehydrated skin;
✔ irregular surface texture;
✔ fine expression lines;
✔ loss of radiance;
✔ early photoageing;
✔ superficial hyperpigmentation;
✔ normal, dry or combination skin;
✔ appropriately selected sensitive skin;
✔ Skin Quality programmes;
✔ periodic revitalisation protocols;
✔ maintenance of skin quality.
The choice should always be made following an individual clinical assessment that takes into account the patient’s medical history, the condition of the skin barrier function, skin sensitivity, previous treatments and therapeutic objectives.
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FOR WHICH TYPE OF PROFESSIONAL HAS IT BEEN DESIGNED?
Malic Peel 15% is intended for professionals who understand that skin revitalisation requires rigorous clinical assessment, appropriate patient selection and individualised therapeutic planning.
It is particularly useful in clinics wishing to develop personalised protocols aimed at improving radiance, texture, superficial hydration and SKIN QUALITY.
Its use requires the correct interpretation of the skin response, evaluation of the clinical evolution and adjustment of both the frequency and sequence of treatment according to each patient’s biological characteristics.
Its versatility makes it possible to design therapeutic strategies adapted to different ages, phototypes and clinical objectives, while always respecting skin physiology.
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THERAPDERMA CLINICAL LADDER™
Each peel responds to a different clinical need
The TherapDerma Clinical Ladder™ does not represent a mandatory progression between peels.
Each solution should be selected according to:
✔ professional diagnosis;
✔ clinical objective;
✔ physiological condition of the skin;
✔ integrity of the skin barrier function;
✔ therapeutic strategy;
✔ expected tolerance;
✔ clinical experience;
✔ evolution observed during treatment.
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Malic Peel 15%
May be considered for:
✔ skin revitalisation;
✔ dull skin;
✔ loss of radiance;
✔ irregular texture;
✔ superficial dehydration;
✔ fine expression lines;
✔ early photoageing;
✔ superficial hyperpigmentation;
✔ Skin Quality protocols;
✔ periodic maintenance;
✔ radiance and revitalisation programmes.
Each protocol should always be adapted to the professional diagnosis and the individual biological response.
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QUICK SELECTION GUIDE
Clinical Objective Option That May Be Considered
Skin revitalisation Malic Peel 15%
Dull skin Malic Peel 15%
Superficial dehydration Malic Peel 15%
Improved radiance Malic Peel 15%
Irregular texture Malic Peel 15%
Early photoageing Malic Peel 15%
Fine lines Malic Peel 15%
Superficial hyperpigmentation Malic Peel 15%
Skin Quality programmes Malic Peel 15%
Maintenance protocols Malic Peel 15%
This guide provides general guidance and does not replace an individual clinical assessment.
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WHY INTEGRATE IT INTO A PROGRESSIVE PROGRAMME?
Skin revitalisation does not depend on a single treatment session.
It should be planned while respecting the physiological mechanisms of epidermal renewal, hydration and recovery.
Within this approach, Malic Peel 15% may be integrated into progressive programmes designed to enhance radiance, improve texture, revitalise the skin and optimise its Skin Quality.
Its use allows the professional to assess the patient’s individual response, reassess the skin barrier function and adapt subsequent sessions according to the clinical evolution observed.
Where indicated, it may also be combined sequentially with mesotherapy, PDRN, biostimulation, LED therapy, radiofrequency or other medical-aesthetic technologies.
The integration of these procedures should always be carried out while respecting the physiological timing of skin recovery.
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THERAPDERMA CLINICAL CONCLUSION
Malic Peel 15% is a clinical tool intended for professionals wishing to incorporate skin revitalisation protocols through progressive epidermal renewal, aimed at improving radiance, refining texture and optimising Skin Quality.
Its ability to promote the physiological reorganisation of the epidermis, enhance superficial hydration and restore a more even and radiant appearance allows it to be integrated into therapeutic strategies intended for patients seeking natural, progressive results that respect skin biology.
Within the TherapDerma Clinical Ladder™, it occupies a specific position for protocols focused on revitalisation, improved radiance and the progressive optimisation of skin quality.
As part of the TherapDerma Clinical Ecosystem™, it may be incorporated into structured programmes based on diagnosis, therapeutic planning and clinical reassessment, offering a scientific, personalised approach that is consistent with skin physiology.
Areas of Application
One peel. Different clinical possibilities depending on the anatomical area, diagnosis and the individual biological response.
Malic Peel 15% TherapDerma may be integrated into different professional protocols for superficial epidermal renewal and skin revitalisation, adapted to different anatomical areas according to the diagnosis, the functional characteristics of the skin and the established clinical objectives.
Thanks to the balance between the exfoliating and moisturising properties of Malic Acid, it enables the development of clinically controlled procedures aimed at improving surface texture, enhancing radiance, promoting greater visual tone uniformity and progressively optimising Skin Quality.
Although the face is one of its principal areas of application, Malic Peel 15% may also be incorporated into protocols intended for other anatomical regions when the clinical assessment confirms adequate skin barrier function and sufficient skin recovery capacity.
Each area presents differences in epidermal thickness, photoexposure, sensitivity, hydration level and biological response. For this reason, the application technique, product quantity, treatment area, exposure time and treatment frequency should be carefully individualised.
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FACE
One of the principal areas of application
The face is one of the regions where Malic Peel 15% may most frequently be incorporated into professional protocols aimed at revitalising the skin and progressively improving its Skin Quality.
Environmental exposure, the gradual loss of radiance, irregular texture, fine expression lines and the early signs of photoageing may progressively alter the appearance of the skin.
Where professionally indicated, the procedure may contribute to improving:
✔ skin texture;
✔ natural radiance;
✔ visual tone uniformity;
✔ superficial hydration;
✔ fine expression lines;
✔ the early signs of photoageing;
✔ SKIN QUALITY.
The intensity of the procedure should be adapted to the different facial regions, paying particular attention to areas with thinner skin and greater sensitivity.
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NECK
Aesthetic continuity within carefully selected protocols
The neck has anatomical and functional characteristics that differ from those of the face, including lower sebaceous gland density, more delicate skin and a greater predisposition to photoageing.
Malic Peel 15% may be considered in this region when the professional assessment confirms adequate skin barrier function and the need to promote progressive skin revitalisation.
Where indicated, it may be incorporated into protocols aimed at improving surface texture, enhancing radiance and maintaining aesthetic continuity between the face and the neck.
The quantity of product, exposure time and treatment frequency should be carefully adjusted according to the clinical response observed.
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DÉCOLLETAGE
Progressive revitalisation of a photoexposed area
The décolletage is continuously exposed to ultraviolet radiation and may present loss of radiance, irregular texture, superficial tone irregularities and the early signs of photoageing.
In appropriately selected patients, Malic Peel 15% may form part of protocols designed to promote superficial renewal and progressively improve the texture, visual tone uniformity and Skin Quality of this region.
Due to the inherent sensitivity of the décolletage, the treatment area, the quantity applied and the treatment frequency should be rigorously individualised.
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BACK OF THE HANDS
Progressive improvement of the superficial appearance
The back of the hands is one of the regions with the greatest cumulative exposure to ultraviolet radiation and environmental factors and may present loss of radiance, irregular texture and visible signs of skin ageing.
Where professionally indicated and where skin barrier function is adequate, Malic Peel 15% may be incorporated into protocols aimed at progressively revitalising this region and optimising skin quality.
Application should always respect the anatomical characteristics of the area, individual sensitivity and the skin’s recovery capacity.
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BACK
Body application within carefully selected protocols
The back may present superficial texture irregularities, residual tone irregularities or loss of skin uniformity.
Where the clinical assessment considers it appropriate, Malic Peel 15% may be incorporated into body protocols designed to promote progressive epidermal renewal and improve skin quality.
It may contribute to:
✔ progressively improving texture;
✔ promoting a more even appearance;
✔ revitalising the skin surface;
✔ enhancing radiance;
✔ optimising SKIN QUALITY.
The treatment area, the total quantity of product and the treatment frequency should be strictly adapted to the clinical response observed.
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CHEST
Localised skin revitalisation protocols
Certain areas of the chest may develop superficial tone irregularities, irregular texture or loss of radiance.
Where skin barrier function, skin integrity and the professional diagnosis permit, Malic Peel 15% may be incorporated into localised protocols designed to progressively improve skin quality.
Application should always be limited to carefully selected areas, avoiding regions with active inflammatory lesions, irritation or impaired skin integrity.
Tolerance, the treatment area and the skin’s recovery capacity should be assessed before each procedure.
CLINICAL GUIDANCE ACCORDING TO THE TREATMENT AREA
Anatomical Area Main Clinical Objective Clinical Considerations
Face Skin revitalisation, improvement of texture, radiance and Skin Quality. Adapt the intensity according to the different facial regions and individual sensitivity.
Neck Maintain aesthetic continuity and promote progressive skin revitalisation. Apply with particular caution due to the thinner skin and increased sensitivity of the area.
Décolletage Progressively improve texture, radiance and visual tone uniformity. Carefully individualise the treatment area, the quantity applied and the treatment frequency.
Back of the Hands Revitalise photoexposed skin and optimise skin quality. Always respect the skin’s recovery capacity and the individual biological response.
Back Promote superficial epidermal renewal and improve texture and Skin Quality. Adapt the quantity of product and the treatment frequency according to the treatment area and the clinical evolution.
Chest Progressively improve skin quality in localised areas. Avoid areas with active inflammatory lesions or impaired skin integrity.
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MULTI-AREA PROTOCOLS
In selected patients, Malic Peel 15% may be incorporated into therapeutic programmes involving the sequential treatment of different anatomical areas.
The selection of treatment areas should not be based exclusively on general aesthetic criteria, but on an individual clinical assessment that considers the physiological condition of each area, the integrity of the skin barrier function, the skin’s recovery capacity and the established therapeutic objectives.
The distribution of treatment areas into different phases allows greater clinical control and more precise adaptation of the protocol to the patient’s individual clinical evolution.
Where indicated, therapeutic planning may combine different anatomical areas while always respecting the physiological intervals between procedures, the biological response observed and the individual clinical tolerance.
Treatment personalisation is one of the fundamental principles of the TherapDerma Clinical Ecosystem™, promoting progressive, safe therapeutic strategies that are consistent with skin physiology.
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CLINICAL CONSIDERATIONS
The application of Malic Peel 15% should always be carried out following an individual clinical assessment.
Before each procedure, the professional should evaluate the condition of the skin barrier function, skin sensitivity, relevant medical history, previous treatments and the skin’s recovery capacity.
The application technique, the quantity of product, the exposure time and the treatment frequency should be adapted to the specific characteristics of each anatomical area and the clinical evolution observed.
The individual biological response is the principal criterion for planning treatment continuity and establishing the most appropriate therapeutic progression.
As with any aesthetic medicine procedure, clinical diagnosis and professional judgement take precedence over any standardised protocol.
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QUICK SUMMARY
Malic Peel 15% may be incorporated into professional protocols intended for:
✔ Face;
✔ Neck;
✔ Décolletage;
✔ Back of the Hands;
✔ Back;
✔ Chest.
Main objectives:
✔ Progressive epidermal renewal;
✔ Skin revitalisation;
✔ Improvement of texture;
✔ Enhanced radiance;
✔ Greater visual tone uniformity;
✔ Optimisation of Skin Quality.
Each procedure should always be adapted to the clinical diagnosis, the anatomical characteristics of the treatment area and the patient’s individual biological response.
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THERAPDERMA CONCLUSION
Malic Peel 15% is a versatile clinical tool for professionals wishing to develop personalised protocols aimed at revitalising the skin, progressively improving texture, enhancing radiance and optimising Skin Quality.
Its application should be carefully adapted to the specific characteristics of each anatomical area, while respecting the skin barrier function, skin sensitivity and the individual’s biological response.
Integrated within the TherapDerma Clinical Ecosystem™, it enables the design of personalised therapeutic strategies for different anatomical areas, providing a progressive, safe and clinically consistent approach that respects skin physiology.
How Does It Work?
How Does It Work?
Understanding the biological process allows more precise protocol planning
Although the application of Malic Peel 15% TherapDerma is carried out over a limited period, the biological response associated with the procedure continues to evolve over the following days.
Each session promotes superficial epidermal renewal, contributing to the reorganisation of the stratum corneum, stimulating the physiological mechanisms of skin renewal and progressively optimising Skin Quality.
Understanding the different stages of this process allows the clinical evolution to be interpreted correctly, the frequency of treatment sessions to be adjusted and realistic expectations to be established for each patient.
Thanks to the balance between its exfoliating and moisturising properties, Malic Acid promotes gradual renewal that is compatible with protocols designed to revitalise the skin while respecting its physiology and the integrity of the skin barrier function.
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EVERYTHING BEGINS AT THE SURFACE OF THE SKIN
The peel first comes into contact with the stratum corneum, the outermost layer of the epidermis.
Over time, the accumulation of corneocytes, photoexposure and the gradual reduction in physiological skin renewal may alter skin texture, reduce radiance and contribute to a less even appearance.
The application of Malic Peel 15% promotes superficial chemical exfoliation that helps reduce cohesion between corneocytes and facilitates their gradual elimination.
This process should always be carried out within a professional treatment plan that respects the integrity of the skin barrier function, individual tolerance and the skin’s recovery capacity.
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STEP 1
Progressive Superficial Chemical Exfoliation
Malic Acid acts primarily on the most superficial layers of the stratum corneum, promoting a gradual reduction in the cohesion between corneocytes.
As a result, superficial desquamation of varying intensity may occur, facilitating the gradual removal of accumulated dead skin cells and preparing the skin for its physiological renewal process.
The intensity of the response does not depend solely on the concentration.
It is also influenced by:
✔ the formulation;
✔ the quantity applied;
✔ the exposure time;
✔ the professional application technique;
✔ the thickness of the stratum corneum;
✔ the functional condition of the skin;
✔ individual sensitivity;
✔ previous treatments.
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STEP 2
Physiological Renewal of the Epidermis
Once exfoliation has begun, the epidermis continues its natural renewal process.
The gradual removal of superficial skin cells promotes a more uniform reorganisation of the stratum corneum and contributes to restoring a smoother skin surface.
This process may be particularly beneficial within personalised protocols intended for:
✔ dull skin;
✔ loss of radiance;
✔ irregular texture;
✔ fine lines;
✔ early photoageing;
✔ superficial tone irregularities.
Clinical evolution should always be assessed individually, avoiding the assumption that more intense desquamation is synonymous with a better clinical response.
STEP 3
Superficial Hydration and Skin Revitalisation
As epidermal renewal progresses, Malic Acid helps maintain adequate hydration of the stratum corneum thanks to its humectant properties.
This balance contributes to the progressive restoration of skin that feels more flexible, comfortable and healthy in appearance.
The results will always depend on the diagnosis, the biological characteristics of the skin and appropriate therapeutic planning.
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STEP 4
Progressive Improvement in Skin Quality
As the epidermis completes its renewal process, the skin surface may develop a more homogeneous organisation.
Within a correctly indicated protocol, the following improvements may gradually be observed:
✔ more even skin texture;
✔ smoother skin to the touch;
✔ enhanced radiance;
✔ a more uniform skin tone appearance;
✔ visible improvement in fine lines;
✔ revitalised-looking skin;
✔ progressive optimisation of Skin Quality.
These changes develop gradually and should always be assessed while respecting the physiological recovery intervals and the integrity of the skin barrier function.
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STEP 5
Progressive Clinical Evolution and Professional Reassessment
The response obtained after each treatment session forms part of a biological process that requires time, observation and reassessment.
Clinical evolution should not depend on automatically increasing either the exposure time or the frequency of treatment sessions.
When the protocol respects the skin’s physiological recovery and the appropriate intervals between procedures, clinical evolution may continue progressively and consistently with the established therapeutic objectives.
Each new treatment session should be decided according to:
✔ the clinical response observed;
✔ recovery of the skin barrier function;
✔ individual tolerance;
✔ the evolution of skin texture;
✔ improvement in radiance;
✔ superficial hydration;
✔ compliance with home care recommendations;
✔ the previously established therapeutic objectives.
Continuation of the protocol should never be considered automatic.
Each new application should be justified through a professional reassessment.
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WHY IS IT IMPORTANT TO MAINTAIN A PROGRESSIVE APPROACH?
Skin revitalisation does not depend on aggressive procedures.
The objective is to stimulate the physiological mechanisms of skin renewal while respecting the skin barrier function and the skin’s natural recovery capacity.
The balanced behaviour of Malic Acid makes it possible to develop progressive protocols aimed at optimising Skin Quality without compromising the skin’s physiological balance.
The intensity of the procedure, the exposure time, the treatment frequency and the duration of the programme should always be adapted according to the clinical response observed.
A DIFFERENT RESPONSE IN EVERY PATIENT
The biological response to Malic Peel 15% varies from one patient to another.
Factors such as age, skin type, epidermal thickness, skin barrier function, degree of photoexposure, previous treatments, home care routine and individual biological characteristics all influence the clinical evolution following each procedure.
For this reason, two patients treated with the same protocol may present different levels of superficial desquamation, recovery time and clinical progression.
The intensity of visible exfoliation should never be interpreted as the main indicator of treatment effectiveness.
Professional assessment should always be based on the overall clinical evolution, the patient’s tolerance, the recovery of the skin barrier function and the progressive achievement of the therapeutic objectives established for each individual case.
Personalisation remains one of the fundamental principles of the TherapDerma Clinical Ecosystem™, allowing each protocol to be adapted according to the patient’s individual biological response.
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SEQUENCE OF THE BIOLOGICAL PROCESS
Application of Malic Peel 15%
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Progressive superficial chemical exfoliation
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Gradual reduction in corneocyte cohesion
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Progressive removal of accumulated superficial cells
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Physiological renewal of the epidermis
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Reorganisation of the stratum corneum
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Maintenance of superficial hydration
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Progressive optimisation of Skin Quality
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Professional reassessment and protocol adaptation
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KEY MECHANISMS OF ACTION
✔ Progressive superficial chemical exfoliation
✔ Physiological epidermal renewal
✔ Reorganisation of the stratum corneum
✔ Maintenance of superficial hydration
✔ Progressive optimisation of Skin Quality
✔ Progressive recovery of natural radiance
✔ Improvement in skin texture
✔ More even skin tone appearance
✔ Revitalised-looking skin
✔ Personalised clinical evolution according to the patient’s biological response
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THERAPDERMA CONCLUSION
Understanding how Malic Peel 15% works enables the professional to make more precise clinical decisions and adapt each protocol to the patient’s individual biological response.
Its mechanism of action combines controlled superficial exfoliation with the progressive reorganisation of the stratum corneum, promoting the physiological renewal of the epidermis, the maintenance of superficial hydration and the gradual recovery of skin that appears more even, radiant and revitalised.
Integrated within the TherapDerma Clinical Ecosystem™, it may be combined with mesotherapy, biostimulation, PDRN, LED therapy or other medical-aesthetic technologies whenever indicated by the therapeutic treatment plan.
More than simply understanding how a chemical peel works, understanding this biological process enables professionals to plan progressive, safe treatments that are consistent with skin physiology, optimising Skin Quality through personalised, clinically grounded protocols.
Mechanism of Action
The science that explains the biological response of Malic Acid
The mechanism of action of Malic Peel 15% TherapDerma is based on the controlled interaction between Malic Acid, the formulation, the pH of the preparation and the individual biological characteristics of the skin.
From a scientific perspective, the objective of the procedure is to promote progressive superficial epidermal renewal, contributing to the reorganisation of the stratum corneum, the optimisation of Skin Quality and the preservation of the functional integrity of the skin barrier.
The clinical response will always depend on the diagnosis, the functional condition of the epidermis, the patient’s biological characteristics and the correct application of the professional protocol.
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ACTION ON THE STRATUM CORNEUM
The stratum corneum constitutes the skin’s first line of protection against the external environment and represents the primary site of action of Malic Peel 15%.
This structure is composed of corneocytes embedded within an organised lipid matrix that maintains superficial cohesion, regulates transepidermal water loss and actively contributes to the skin barrier function.
Sun exposure, skin ageing, physiological alterations in epidermal renewal and other environmental factors may progressively modify the organisation of this layer, leading to skin that appears duller, more irregular and less radiant.
Where an appropriate clinical indication exists, Malic Peel 15% acts on this structure by promoting the progressive reorganisation of the skin microrelief through the characteristic biochemical mechanisms of Alpha Hydroxy Acids (AHAs).
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MODULATION OF COHESION BETWEEN CORNEOCYTES
Superficial corneocytes remain attached through specialised protein structures known as corneodesmosomes.
Malic Acid promotes a progressive reduction in the cohesion between these cellular junctions, facilitating the physiological desquamation of corneocytes that have completed their biological life cycle.
This mechanism reproduces a natural process of skin renewal, promoting a more uniform reorganisation of the stratum corneum without disrupting normal physiological processes when applied under professional supervision.
As a result of this physiological process, the skin surface may progressively develop a more homogeneous texture, greater softness and a more radiant appearance.
The intensity of this response will always depend on the individual characteristics of the skin and the selected treatment protocol.
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EPIDERMAL RENEWAL AND SKIN REVITALISATION
Epidermal renewal is a continuous physiological process through which keratinocytes migrate from the deepest layers of the epidermis until they become functional corneocytes.
The correct organisation of this cycle is essential for maintaining an even skin surface, adequate hydration and an effective skin barrier function.
When this process becomes less efficient, dead skin cells may accumulate, reducing radiance and altering the superficial texture.
By promoting controlled superficial chemical exfoliation, Malic Peel 15% contributes to a more organised renewal process, allowing the progressive recovery of skin that appears more even, radiant and revitalised.
BALANCE BETWEEN EXFOLIATION AND HYDRATION
One of the distinguishing characteristics of Malic Acid is its ability to combine superficial chemical exfoliation with humectant properties that help preserve the hydration of the stratum corneum.
This balance supports epidermal renewal protocols that respect skin physiology and contributes to maintaining skin that is more flexible, comfortable and healthy-looking throughout the course of treatment.
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RELATIONSHIP BETWEEN CONCENTRATION, pH AND SKIN RESPONSE
The nominal concentration represents only one of the many factors that influence the clinical behaviour of a chemical peel.
The biological response is also determined by the interaction of several variables:
✔ the pH of the formulation;
✔ the fraction of acid available in its non-ionised form;
✔ the vehicle used;
✔ the actual contact time with the skin;
✔ the application technique;
✔ the preparation of the skin surface prior to treatment;
✔ the hydration level of the stratum corneum;
✔ the integrity of the skin barrier function;
✔ the patient’s individual sensitivity.
For this reason, two formulations with the same nominal concentration may produce different clinical responses.
Professional assessment should always take all of these variables into consideration before determining the intensity of the procedure.
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INTEGRATION INTO THERAPEUTIC PROTOCOLS
The clinical versatility of Malic Peel 15% allows it to be incorporated into sequential therapeutic strategies whenever indicated by the clinical diagnosis.
Treatment planning should always respect the physiological recovery time of the epidermis before introducing any complementary procedure.
Once the skin barrier function has been restored, the professional may evaluate its integration into combined Skin Quality, biostimulation, PDRN, regenerative mesotherapy or medical-aesthetic technology protocols, selecting each intervention according to the patient’s clinical needs.
The combination of procedures should never follow a predetermined sequence, but should always be based on an individualised treatment plan guided by the clinical evolution observed.
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SCIENCE AT A GLANCE™
Parameter Malic Peel 15%
Active Ingredient Malic Acid
Chemical Family Alpha Hydroxy Acids (AHAs)
Primary Site of Action Stratum corneum
Predominant Mechanism Progressive reduction in cohesion between corneocytes
Associated Physiological Process Epidermal renewal and reorganisation of the stratum corneum
Expected Physiological Outcome Progressive skin revitalisation and optimisation of Skin Quality
Key Determining Variables pH, formulation, application technique, exposure time and the individual’s skin characteristics
Clinical Purpose To promote progressive epidermal renewal within personalised treatment protocols
BIOLOGICAL FOUNDATION
The clinical behaviour of a chemical peel depends on the biological response developed by the epidermis following application of the active ingredient, and not exclusively on its nominal concentration.
In the case of Malic Acid, its interaction with the stratum corneum promotes the progressive reorganisation of the epidermal surface through physiological mechanisms that contribute to improving skin texture, enhancing radiance and optimising Skin Quality.
Treatment outcomes will depend on each patient’s biological response capacity, the functional condition of the skin and the correct clinical planning carried out by the professional.
For this reason, interpreting the mechanism of action requires the integration of scientific knowledge with clinical observation, allowing each protocol to be adapted according to the specific biological evolution of every patient.
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SCIENTIFIC PRINCIPLES OF USE
The interpretation of the mechanism of action should be based on several fundamental principles:
✔ the biological response is always individual;
✔ concentration alone does not determine the clinical behaviour of the treatment;
✔ the skin barrier function influences both tolerance and treatment progression;
✔ hydration of the stratum corneum influences the clinical response;
✔ protocol planning is more important than the isolated intensity of each treatment session;
✔ clinical reassessment allows the treatment to be adapted according to the observed clinical evolution;
✔ the quality of the final outcome depends on the combination of diagnosis, appropriate indication and correct execution of the procedure.
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THERAPDERMA CONCLUSION
Understanding the mechanism of action of Malic Peel 15% means understanding how the skin responds to a carefully controlled superficial chemical exfoliation.
Its effectiveness does not depend exclusively on the acid concentration, but on the interaction between the formulation, the pH, the application technique and the biological characteristics of each patient.
This perspective allows the clinical response to be interpreted from a scientific standpoint, supporting more precise, personalised treatment protocols that are consistent with skin physiology.
Integrated within the TherapDerma Clinical Ecosystem™, this knowledge provides the foundation for incorporating Malic Peel 15% into therapeutic strategies aimed at optimising Skin Quality, while always respecting each patient’s individual biological evolution.
Scientific Foundations
The formulation determines the clinical behaviour
In a professional chemical peel, the acid concentration represents only one of the many factors involved in the skin’s biological response.
The clinical behaviour of a formulation depends on the interaction between its physicochemical properties, the functional availability of the active ingredient, the application technique and each patient’s individual biological characteristics.
For this reason, formulations that appear similar may exhibit different clinical profiles, even when they contain the same nominal acid concentration.
From this perspective, Malic Peel 15% TherapDerma has been developed for integration into professional treatment protocols in which the complete formulation is considered an essential factor in achieving a predictable, reproducible clinical response that is consistent with skin physiology.
The scientific evaluation of a chemical peel should always consider all of these factors collectively, rather than focusing solely on the declared percentage of the active ingredient.
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CONCENTRATION
An important parameter, but never sufficient on its own
Concentration expresses the nominal amount of Malic Acid present in the formulation, but by itself it does not determine the intensity or clinical behaviour of the procedure.
Two peels with the same concentration may produce different clinical responses when variations exist in pH, the vehicle, formulation stability, exposure time or the physiological condition of the skin.
For this reason, concentration should be interpreted as one of the parameters that guides clinical treatment selection, always as part of a comprehensive professional assessment.
In Malic Peel 15%, the concentration of the active ingredient has been selected to support protocols of progressive superficial chemical exfoliation, epidermal renewal and Skin Quality optimisation while respecting each patient’s individual biological evolution.
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THE ROLE OF pH
A regulator of chemical equilibrium
pH is one of the most important physicochemical parameters in the design of a professional chemical peel.
Beyond indicating the degree of acidity of the formulation, it participates in the chemical equilibrium of the acid and influences the proportion of functionally available molecules during the procedure.
Small variations in pH may alter the clinical behaviour of formulations with a similar nominal concentration by influencing the interaction between the active ingredient and the stratum corneum.
For this reason, pH represents one of the principal regulators of formulation behaviour and contributes to the predictability, reproducibility and safety of the clinical procedure.
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THE SIGNIFICANCE OF pKa
Understanding the chemical equilibrium of Malic Acid
pKa is a physicochemical property specific to each acid and describes the equilibrium between its ionised and non-ionised forms according to the pH of the surrounding environment.
Malic Acid has two characteristic dissociation constants (pKa₁ ≈ 3.40 and pKa₂ ≈ 5.11), reflecting its dicarboxylic molecular structure.
These values help explain how the chemical availability of the active ingredient may vary between different formulations, although they cannot by themselves predict the clinical response obtained.
Their true scientific value lies in facilitating the interpretation of the formulation’s chemical behaviour when considered together with pH, the professional application technique and the biological characteristics of the skin.
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PHYSICOCHEMICAL PROFILE OF MALIC ACID
Scientific characteristics of the active ingredient
Malic Acid belongs to the Alpha Hydroxy Acid (AHA) family and occurs naturally in various fruits, particularly apples, where it plays a role in numerous plant metabolic processes.
Chemically, it is a water-soluble dicarboxylic acid whose molecular structure makes it particularly suitable for formulations designed to provide progressive superficial chemical exfoliation.
These properties, combined with a professionally developed formulation, contribute to gradual epidermal renewal and the progressive optimisation of Skin Quality.
SCIENTIFIC MOLECULAR PROFILE™
Parameter Malic Acid
Chemical Name Malic Acid
Chemical Family Alpha Hydroxy Acid (AHA)
Molecular Formula C₄H₆O₅
Molecular Weight 134.09 g/mol
Chemical Nature Water-soluble dicarboxylic acid
pKa₁ ≈ 3.40
pKa₂ ≈ 5.11
Natural Sources Apples, pears and other fruits
Primary Site of Action Stratum corneum
Type of Exfoliation Progressive superficial chemical exfoliation
The clinical relevance of these characteristics lies not only in the molecular properties of the active ingredient, but also in the interaction between the active ingredient, the complete formulation and skin biology, enabling professional protocols based on controlled exfoliation, progressive epidermal renewal and the gradual optimisation of Skin Quality.
WHY CAN TWO PEELS BEHAVE DIFFERENTLY?
Much more than the acid concentration
Although two peels may contain the same active ingredient or an apparently similar nominal concentration, their clinical behaviour may differ significantly.
The biological response observed during the procedure depends on the simultaneous interaction of physicochemical, technical and biological factors that determine the functional availability of the active ingredient and the way it interacts with the epidermis.
The main variables influencing this behaviour include:
✔ nominal concentration of Malic Acid;
✔ formulation pH;
✔ chemical equilibrium determined by the pKa;
✔ composition of the vehicle and excipients;
✔ formulation stability;
✔ professional application technique;
✔ number of layers applied;
✔ effective exposure time;
✔ functional condition of the skin barrier;
✔ hydration of the stratum corneum;
✔ individual biological sensitivity.
For this reason, the scientific interpretation of a chemical peel should always consider the combined interaction of all these factors rather than the acid concentration in isolation.
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THE VEHICLE AND THE FORMULATION
The invisible architecture of the peel
In addition to the active ingredient, every formulation contains a vehicle and a combination of excipients that determine how the product is distributed across the skin and how it maintains its stability throughout the procedure.
These components influence the uniformity of application, the functional availability of Malic Acid and the clinical reproducibility of the treatment.
A properly developed formulation promotes more stable, homogeneous and predictable behaviour, allowing consistent results to be achieved within standardised professional treatment protocols.
From a scientific perspective, the formulation should therefore be understood as a complete system rather than simply as an acid concentration.
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EXPOSURE TIME
A variable that must be individualised
The length of time the formulation remains in contact with the skin is one of the clinical factors that most strongly influences the progression of the procedure.
Its duration should always be determined according to the diagnosis, the treatment area, the thickness of the stratum corneum, the observed tolerance and the clinical response obtained during the session.
There is no universal exposure time that is appropriate for every patient.
Continuous observation of the skin response allows the procedure to be adjusted whenever necessary, promoting greater safety and a more predictable clinical outcome.
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SKIN BARRIER FUNCTION
The foundation of an appropriate physiological response
The integrity of the skin barrier is one of the principal factors influencing both tolerance and the biological response to any chemical peel.
A functional skin barrier helps maintain epidermal homeostasis, regulates transepidermal water loss and preserves the physiological balance of the skin surface.
Factors such as hydration of the stratum corneum, environmental exposure, previous treatments or certain dermatological conditions may modify the clinical response to the procedure.
For this reason, the initial assessment of skin barrier function is an essential step in selecting safer treatment protocols that are appropriately tailored to each patient’s specific needs.
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BIOLOGICAL VARIABILITY
Every skin responds differently
The biological response to a chemical peel is never identical between two patients.
Age, skin phototype, epidermal hydration, stratum corneum thickness, sebaceous activity, skin sensitivity, environmental exposure and previous treatments may all influence the clinical evolution of the treatment.
Even when using the same formulation and following exactly the same protocol, the physiological response may differ significantly between individuals.
For this reason, every procedure should be adapted according to the clinical evolution observed through continuous reassessment throughout the course of treatment.
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FACTORS THAT INFLUENCE THE CLINICAL RESPONSE
An integrated view of the procedure
The final clinical response does not depend on a single factor, but on the dynamic interaction between the formulation, the procedure and the patient’s biological characteristics.
FORMULATION
✔ Active ingredient concentration.
✔ pH.
✔ pKa.
✔ Vehicle and excipients.
✔ Physicochemical stability.
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PROCEDURE
✔ Skin preparation.
✔ Application technique.
✔ Number of layers applied.
✔ Exposure time.
✔ Neutralisation, where indicated.
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PATIENT
✔ Skin barrier function.
✔ Epidermal hydration.
✔ Skin phototype.
✔ Individual sensitivity.
✔ Clinical diagnosis.
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BIOLOGICAL RESPONSE
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CLINICAL OUTCOME
This integrated approach makes it possible to develop safer, more reproducible and more personalised treatment protocols, adapting each procedure to the observed biological response while promoting results that are consistent with skin physiology.
SCIENCE AT A GLANCE™
Parameter Malic Peel 15%
Active Ingredient Malic Acid
Concentration 15%
Primary Site of Action Stratum corneum
Type of Exfoliation Progressive superficial chemical exfoliation
Predominant Mechanism Progressive reduction in corneocyte cohesion
Primary Physiological Process Epidermal renewal and reorganisation of the stratum corneum
Expected Physiological Outcome Progressive revitalisation and optimisation of Skin Quality
Key Clinical Variables Formulation, pH, pKa, application technique, exposure time and individual biological response
Clinical Purpose To promote progressive epidermal renewal within personalised professional treatment protocols
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SCIENTIFIC FORMULATION PROFILE™
Technical characteristics of the formulation
Parameter Malic Peel 15%
Active Ingredient Malic Acid
Chemical Family Alpha Hydroxy Acid (AHA)
Molecular Formula C₄H₆O₅
Molecular Weight 134.09 g/mol
Chemical Nature Water-soluble dicarboxylic acid
pKa₁ ≈ 3.40
pKa₂ ≈ 5.11
Natural Sources Apples, pears and other fruits
Professional Presentation 50 mL
Intended Use Professional use only
Note: The clinical behaviour of the formulation will always depend on the interaction between its physicochemical properties, the treatment protocol applied and each patient’s individual biological characteristics.
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NEUTRALISATION
Restoring physiological balance
Neutralisation is an essential stage whenever it is specified by the protocol of the chemical peel being performed.
Its purpose is to stop the activity of the formulation in a controlled manner, promoting the progressive restoration of the skin surface’s physiological balance while initiating the epidermal recovery phase.
The decision to neutralise should always be based on the professional treatment protocol, the effective exposure time and the clinical response observed during the session.
When performed correctly, neutralisation contributes to improving the safety, reproducibility and predictability of the procedure.
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APPLYING SCIENTIFIC KNOWLEDGE
From the laboratory to clinical practice
Understanding the physicochemical properties of a formulation allows a more accurate interpretation of the peel’s behaviour during the clinical procedure.
Integrating this knowledge with patient assessment facilitates the selection of the most appropriate treatment protocol, the progressive adaptation of the procedure and the optimisation of the observed biological response.
In this way, scientific evidence becomes more than theoretical knowledge—it becomes a practical tool that supports informed clinical decision-making.
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SCIENTIFIC NOTE
The physicochemical properties of a formulation help explain its potential behaviour but never replace the clinical assessment performed by the healthcare professional.
The clinical evolution of the treatment will always depend on the interaction between the formulation, the application technique and each patient’s individual biological response.
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THERAPDERMA SCIENTIFIC INSIGHT™
Correctly interpreting a formulation means understanding how the chemistry of the active ingredient, the complete formulation and skin biology interact throughout the entire procedure.
This scientific approach enables the development of safer, more reproducible and physiologically consistent treatment protocols, supporting therapeutic strategies designed to revitalise the skin, progressively improve its radiance and optimise Skin Quality.
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THERAPDERMA CONCLUSION
The true strength of a professional chemical peel does not lie solely in the concentration of its active ingredient, but in the professional’s ability to interpret the overall behaviour of the formulation and adapt every procedure to each patient’s specific biological response.
Integrating physicochemical knowledge with clinical assessment makes it possible to develop more precise, safer and more reproducible treatment protocols while fully respecting skin physiology and the individual progression of treatment.
As part of the TherapDerma Clinical Ecosystem™, Malic Peel 15% is a professional therapeutic solution designed to integrate into clinical strategies focused on the progressive optimisation of Skin Quality, combining scientific evidence, individualised diagnosis and personalised treatment planning.
Indications
When should Malic Peel 15% be chosen?
The indication for a professional chemical peel should always be based on a comprehensive clinical assessment and the definition of specific therapeutic objectives.
Beyond the acid concentration, the decision depends on the skin’s biological characteristics, the condition of the skin barrier function and the clinical outcomes that are intended to be achieved.
Within this context, Malic Peel 15% may be incorporated when the practitioner considers progressive superficial epidermal renewal appropriate in order to revitalise the skin, enhance its radiance and optimise Skin Quality, always within properly planned personalised treatment protocols.
Each indication should be established individually, avoiding standardised protocols and adapting the treatment to each patient’s clinical progression.
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PATIENT PROFILE
What characteristics are commonly observed?
Malic Peel 15% may be considered for patients presenting superficial skin changes that may benefit from progressive epidermal renewal and an improvement in Skin Quality.
These patients commonly present one or more of the following characteristics:
✔ loss of radiance;
✔ dull or devitalised skin;
✔ uneven skin texture;
✔ fine expression lines;
✔ superficial skin tone irregularities;
✔ early signs of photoageing;
✔ the need to improve overall skin quality.
The presence of one or more of these characteristics alone does not constitute an automatic indication. The final decision will always depend on the professional clinical assessment and the established therapeutic plan.
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MAIN CLINICAL INDICATIONS
Malic Peel 15% may be incorporated into professional treatment protocols aimed at:
✔ dull or devitalised skin;
✔ loss of radiance;
✔ uneven superficial skin texture;
✔ superficial skin tone irregularities;
✔ fine expression lines;
✔ early signs of photoageing;
✔ progressive improvement of Skin Quality;
✔ Skin Quality programmes.
Each of these indications requires specific planning and may be integrated into different therapeutic strategies.
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DULL OR DEVITALISED SKIN
The progressive reduction in epidermal renewal together with continuous exposure to environmental factors may contribute to skin that appears tired, less radiant and less even in texture.
In these cases, Malic Peel 15% may form part of treatment protocols designed to progressively revitalise the skin surface.
The usual treatment objectives include:
✔ increasing radiance;
✔ promoting a fresher-looking complexion;
✔ improving superficial skin texture;
✔ optimising Skin Quality;
✔ promoting a healthier appearance.
The treatment protocol should always be adapted to the clinical characteristics observed in each patient.
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SUPERFICIAL SKIN TONE IRREGULARITIES
Visible variations in skin colour may have different causes and always require prior clinical assessment.
When the alteration is located predominantly within the most superficial layers of the epidermis, Malic Peel 15% may be incorporated into treatment protocols aimed at promoting a more even appearance.
Before establishing the indication, the practitioner should assess:
✔ the origin of the alteration;
✔ the distribution of the lesions;
✔ skin phototype;
✔ pigmentation history;
✔ recent sun exposure;
✔ the clinical objectives of the treatment.
Treatment planning should always be accompanied by photoprotection measures and appropriate clinical follow-up.
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UNEVEN SKIN TEXTURE
Alterations in the skin microrelief may be associated with physiological ageing, photoexposure or less efficient epidermal renewal.
When these changes are predominantly superficial, Malic Peel 15% may be incorporated into treatment protocols designed to promote a visibly smoother and more even skin surface.
Clinical objectives may include:
✔ improving skin texture;
✔ smoothing the skin microrelief;
✔ promoting a more even skin surface;
✔ increasing radiance;
✔ optimising Skin Quality.
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EARLY PHOTOAGEING
The first signs of photoageing commonly present as loss of radiance, uneven skin texture and reduced uniformity of skin tone.
In appropriately selected patients, Malic Peel 15% may form part of treatment programmes designed to progressively improve these superficial changes.
The usual treatment objectives include:
✔ revitalising the skin;
✔ improving skin texture;
✔ promoting greater radiance;
✔ optimising skin tone uniformity;
✔ progressively improving Skin Quality.
Clinical progression will depend on treatment consistency, daily photoprotection and adherence to the recommended home care programme.
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FINE EXPRESSION LINES
Fine lines are among the earliest visible signs of skin ageing and may become more pronounced as a result of dehydration and the reduced physiological renewal of the epidermis.
Within properly planned treatment protocols, Malic Peel 15% may contribute to improving the overall appearance of these superficial lines through progressive epidermal renewal and revitalisation of the skin surface.
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CLINICAL TREATMENT OBJECTIVES
The decision to use Malic Peel 15% should always be based on clearly defined clinical objectives before initiating the treatment protocol.
The most common objectives include:
✔ optimising Skin Quality;
✔ increasing radiance;
✔ promoting a more even skin texture;
✔ optimising superficial hydration;
✔ improving the visual uniformity of skin tone;
✔ complementing professional Skin Quality programmes;
✔ progressively revitalising the skin.
Defining treatment objectives in advance facilitates treatment planning and allows a more accurate assessment of the patient’s clinical progression.
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CRITERIA FOR SELECTING MALIC PEEL 15%
The decision to use Malic Peel 15% should be based on a comprehensive patient assessment and on the correspondence between the observed clinical characteristics and the established therapeutic objectives.
Before recommending Malic Peel 15%, it is advisable to confirm:
✔ that the skin changes to be treated are predominantly superficial;
✔ that there is a clearly defined clinical indication;
✔ that the patient understands the treatment objectives;
✔ that appropriate clinical follow-up can be carried out;
✔ that the selected treatment protocol is consistent with the expected clinical progression.
The concentration represents only one of the factors involved in therapeutic planning and should never be considered an isolated decision-making criterion.
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WHEN SHOULD MALIC PEEL 15% BE CHOSEN?
Malic Peel 15% may represent an excellent option when the primary objective is to:
✔ revitalise dull skin;
✔ improve radiance;
✔ optimise superficial skin texture;
✔ promote progressive epidermal renewal;
✔ develop Skin Quality programmes;
✔ complement skin rejuvenation protocols;
✔ maintain a therapeutic strategy that respects skin physiology.
The decision should always be based on the clinical diagnosis and the therapeutic objectives established for each patient.
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SUMMARY OF THE MAIN INDICATIONS
Malic Peel 15% may be considered within professional treatment protocols for patients presenting:
✔ dull or devitalised skin;
✔ loss of radiance;
✔ uneven superficial skin texture;
✔ fine expression lines;
✔ superficial skin tone irregularities;
✔ early signs of photoageing;
✔ reduced Skin Quality;
✔ the need for Skin Quality programmes.
These indications provide general clinical guidance and should always be interpreted within the context of the individual assessment performed by the practitioner.
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THERAPDERMA CLINICAL CONCLUSION
Appropriate patient selection is one of the factors that most strongly influences treatment safety, clinical consistency and patient satisfaction.
Malic Peel 15% has been developed for integration into professional treatment protocols intended for patients who may benefit from progressive superficial epidermal renewal designed to revitalise the skin, enhance its radiance and optimise Skin Quality.
The decision to use this chemical peel should always be based on a thorough clinical assessment, clearly defined therapeutic objectives and an individualised treatment plan adapted to each patient’s clinical progression.
Within the TherapDerma Clinical Ecosystem™, Malic Peel 15% represents a clinical solution designed to integrate into personalised Skin Quality programmes, supporting professional practice based on scientific evidence, therapeutic individualisation and respect for skin physiology.
Contraindications
Safety begins before treatment
The decision to perform a professional chemical peel does not depend solely on the presence of a clinical indication. Before initiating any procedure, it is essential to identify those situations that may compromise patient safety or modify the expected response to treatment.
Early identification of contraindications helps reduce the risk of complications, determine the most appropriate time to intervene or, when necessary, choose an alternative therapeutic strategy.
Safe clinical practice is not limited to knowing when to treat, but also to recognising when it is preferable to postpone or avoid the procedure.
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ABSOLUTE CONTRAINDICATIONS
The following situations contraindicate the use of Malic Peel 15% until the underlying cause has resolved or a new clinical assessment allows the treatment to be reconsidered.
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PREGNANCY AND BREASTFEEDING
As a precautionary measure, chemical peels are not recommended during pregnancy or while breastfeeding.
Although the systemic absorption of topically applied Malic Acid is very limited, there are currently insufficient clinical data to support its routine use during these periods.
Patient safety should always take precedence over any aesthetic objective.
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ACTIVE SKIN INFECTIONS
Malic Peel 15% must not be applied to skin presenting active infectious processes, as inflammation and tissue alteration may modify the skin’s behaviour during the procedure.
The main situations include:
✔ active herpes simplex;
✔ bacterial infections;
✔ viral infections;
✔ fungal infections;
✔ pustular lesions of infectious origin;
✔ any inflammatory process associated with infection.
Treatment may only be reconsidered once the infectious process has completely resolved and the skin has fully regained its clinical integrity.
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WOUNDS AND LOSS OF SKIN INTEGRITY
The procedure must not be performed on areas presenting visible disruption of the skin surface.
This includes:
✔ open wounds;
✔ abrasions;
✔ erosions;
✔ fissures;
✔ excoriations;
✔ recent burns;
✔ sunburn;
✔ areas that have undergone surgical or traumatic procedures with incomplete healing.
The skin should be fully recovered before any chemical exfoliation procedure is considered.
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ACTIVE INFLAMMATORY DERMATOSES
The presence of active inflammatory skin diseases within the treatment area temporarily contraindicates the procedure.
These include:
✔ dermatitis;
✔ eczema;
✔ active psoriasis;
✔ inflammatory rosacea;
✔ contact dermatitis;
✔ uncontrolled seborrhoeic dermatitis;
✔ other dermatoses associated with inflammation or disruption of the epidermis.
The procedure should only be reconsidered once the condition has stabilised and the clinical assessment confirms full skin recovery.
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HYPERSENSITIVITY TO THE FORMULATION
Malic Peel 15% is contraindicated in patients with a known history of hypersensitivity to Malic Acid or to any component of the formulation.
Where there is any history of allergic reaction, significant intolerance or an unexpected response to similar procedures, an individual assessment should be performed before considering treatment.
Previous tolerance to other Alpha Hydroxy Acids (AHAs) does not necessarily imply an equivalent response to Malic Acid.
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EXTREMELY REACTIVE SKIN
In patients with a marked tendency to develop exaggerated skin reactions, the practitioner should carefully assess the suitability of the procedure.
Particular attention should be paid when there is a history of:
✔ persistent irritation;
✔ recurrent episodes of dermatitis;
✔ intolerance to multiple cosmetic products;
✔ intense reactions following superficial procedures;
✔ disproportionate skin sensitivity.
In such cases, it may be preferable to stabilise the skin beforehand or to select an alternative therapeutic strategy according to clinical judgement.
TEMPORARY CONTRAINDICATIONS
Certain circumstances do not permanently contraindicate the use of Malic Peel 15%, but make it advisable to postpone the procedure until the skin has regained its normal physiological condition.
The decision should always be based on the observed clinical progression and not solely on a predetermined time interval.
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RECENT DERMATOLOGICAL OR AESTHETIC TREATMENTS
Before recommending the peel, it is essential to identify any procedures performed during the preceding weeks, as some may temporarily modify the skin’s response.
Particular attention should be given to patients who have recently undergone:
✔ topical or oral retinoid therapy;
✔ other exfoliating agents;
✔ keratolytic treatments;
✔ laser procedures;
✔ skin resurfacing;
✔ dermabrasion or microdermabrasion;
✔ microneedling;
✔ other chemical peels.
The use of Malic Peel 15% should be postponed until complete skin recovery has been confirmed and there are no remaining clinical signs of irritation.
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HAIR REMOVAL AND PROCEDURES THAT INCREASE SKIN SENSITIVITY
Certain cosmetic procedures may temporarily disrupt the skin surface and increase sensitivity to the treatment.
These include:
✔ waxing;
✔ thread hair removal;
✔ depilatory creams;
✔ electrolysis;
✔ particularly aggressive shaving;
✔ intensive extractions;
✔ similar procedures that may sensitise the skin.
Treatment should be postponed until it has been confirmed that the treated area has fully returned to its normal condition.
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RECENT SUN EXPOSURE
It is not advisable to initiate a treatment protocol when the skin shows signs of intense sun exposure, sunburn or a recent tan.
Likewise, the procedure should be postponed if the patient anticipates significant sun exposure during the recovery period and cannot ensure appropriate photoprotection.
Treatment scheduling should always be adapted to each patient’s individual clinical circumstances.
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SITUATIONS REQUIRING SPECIFIC CLINICAL ASSESSMENT
Certain circumstances do not constitute an absolute contraindication but require a more detailed assessment before deciding whether to perform the procedure.
These include:
✔ a history of post-inflammatory hyperpigmentation;
✔ a tendency towards hypertrophic or keloid scarring;
✔ systemic diseases that may affect skin repair;
✔ pharmacological treatments that may influence the skin’s response;
✔ a history of severe reactions to aesthetic procedures;
✔ medical conditions requiring additional clinical assessment.
In these situations, the treatment protocol should be individualised after carefully evaluating the balance between the expected benefits and the potential clinical risks.
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PHARMACOLOGICAL TREATMENTS
Reviewing the patient’s regular medication forms part of the pre-treatment assessment.
Particular attention should be given to medications that may:
✔ increase photosensitivity;
✔ modify the inflammatory response;
✔ impair wound healing;
✔ interfere with the normal processes of skin recovery.
Where there is any uncertainty regarding the compatibility of the patient’s medication with the procedure, it is advisable to seek an assessment from the responsible healthcare professional before proceeding.
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PATIENT COMPLIANCE
The safety of the procedure also depends on the patient’s ability to follow professional recommendations correctly.
Treatment should be reconsidered where there is a high probability of non-compliance with essential aspects such as:
✔ post-treatment care;
✔ daily use of photoprotection;
✔ scheduled follow-up appointments;
✔ instructions regarding home care products.
The patient’s active cooperation is an essential element in minimising risks and promoting an appropriate clinical outcome.
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PRE-PROCEDURE CLINICAL CHECKLIST
Before performing Malic Peel 15%, it is recommended to confirm that all essential safety criteria have been verified.
☐ The skin is intact and free from visible lesions.
☐ There are no signs of active skin infection.
☐ There are no inflammatory dermatoses within the treatment area.
☐ The patient is not pregnant or breastfeeding.
☐ There is no known history of hypersensitivity to the formulation.
☐ Recent medical and aesthetic treatments have been reviewed.
☐ There has been no recent sun exposure that may interfere with the procedure.
☐ The risk of pigmentary alterations has been assessed where appropriate.
☐ The patient understands the recommendations before and after treatment.
☐ A clearly defined clinical indication has been established.
☐ All the necessary materials are available to perform the procedure in accordance with the professional treatment protocol.
A systematic assessment before every treatment session helps maintain a high standard of safety and supports more consistent clinical decision-making.
CLINICAL DECISION IN THE PRESENCE OF A POSSIBLE CONTRAINDICATION
The identification of a contraindication does not always imply the definitive cancellation of treatment.
Depending on the clinical situation, the practitioner may choose one of the following approaches:
POSTPONE THE PROCEDURE
When the identified condition is temporary and may resolve over time or following the physiological recovery of the skin.
MODIFY THE THERAPEUTIC STRATEGY
When an alternative treatment is more appropriate for the patient’s clinical characteristics or treatment objectives.
REQUEST MEDICAL ASSESSMENT
When diseases, pharmacological treatments or clinical circumstances require further medical evaluation before proceeding.
DO NOT PERFORM THE PROCEDURE
When the potential risk clearly outweighs the expected benefit or when adequate safety conditions cannot be guaranteed.
The decision not to proceed with treatment, when clinically justified, also forms part of responsible professional practice.
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PRINCIPLES OF CLINICAL SAFETY
The prevention of complications begins long before the chemical peel is applied.
A thorough clinical assessment makes it possible to:
✔ identify risk factors before treatment;
✔ select the most appropriate time to intervene;
✔ adapt the therapeutic strategy to the patient’s characteristics;
✔ reduce the likelihood of undesirable responses;
✔ promote safer and more predictable procedures.
Safety should be understood as a continuous process that accompanies every stage of treatment, from the initial consultation through to the final assessment of the clinical outcomes.
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THERAPDERMA CONCLUSION
The identification of contraindications is one of the fundamental pillars of safe clinical practice in professional chemical peels.
Before every treatment session, the practitioner should confirm that the skin meets the appropriate conditions for treatment and that the expected benefits fully justify performing the procedure.
Recognising the appropriate moment to proceed with treatment, postpone it or even decide against it forms part of responsible clinical decision-making and represents an essential element in minimising risks and promoting a predictable clinical outcome.
Within the TherapDerma Clinical Ecosystem™, Malic Peel 15% is integrated into a model of patient care based on individual patient assessment, the prevention of complications and the rigorous application of protocols supported by scientific evidence.
Professional Application
A procedure based on precision, clinical observation and personalisation
The quality of a professional chemical peel does not depend solely on the formulation used, but also on the way in which each treatment session is planned, performed and monitored.
Every treatment should be adapted to the individual characteristics of the skin, the anatomical area being treated and the skin response observed during the procedure.
Malic Peel 15% has been developed exclusively for professional use and should be applied following a structured treatment protocol, in which each stage contributes to ensuring a safe, precise procedure that respects skin physiology.
Appropriate patient preparation, a consistent application technique and continuous observation of the clinical progression constitute the pillars of a controlled and reproducible professional practice.
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PATIENT PREPARATION
Preparation begins before the day of the treatment session and aims to create the most favourable conditions for carrying out the procedure.
According to the clinical assessment and the patient’s individual characteristics, the practitioner may temporarily recommend:
✔ avoiding intense sun exposure;
✔ maintaining appropriate daily photoprotection;
✔ discontinuing, where appropriate, potentially irritating cosmetic products;
✔ avoiding physical or chemical exfoliants;
✔ avoiding procedures that may sensitise the skin before the session;
✔ maintaining a gentle home care routine compatible with the treatment;
✔ reporting any significant changes in the condition of the skin before the procedure.
These recommendations should always be individualised and adapted to each patient’s needs.
Before beginning the session, it is essential to confirm that the skin is stable and meets the appropriate conditions for treatment.
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SKIN PREPARATION
Appropriate preparation facilitates the uniform application of the peel and allows greater control of the procedure.
Before starting, the practitioner should:
✔ carefully cleanse the treatment area;
✔ remove make-up, sunscreen and other cosmetic residues;
✔ remove superficial impurities;
✔ perform degreasing only when indicated by the treatment protocol;
✔ dry the skin surface completely;
✔ confirm that there are no visible lesions incompatible with the procedure.
All preparation should be carried out gently, avoiding manoeuvres that may unnecessarily increase skin sensitivity.
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PROTECTION OF SENSITIVE AREAS
Before applying Malic Peel 15%, it is advisable to identify those areas requiring specific protection in order to minimise the risk of accidental contact.
These may include:
✔ the eye contour;
✔ the lips and mucous membranes;
✔ the corners of the mouth;
✔ the nasal alae;
✔ skin folds;
✔ recently treated areas;
✔ particularly sensitive areas.
Protection should be applied precisely, avoiding interference with the treatment area.
The practitioner should also prevent the product from coming into contact with the eyes, mucous membranes or any area not included within the treatment protocol.
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PEEL APPLICATION
Malic Peel 15% should be applied in a uniform and methodical manner, strictly following the established professional treatment protocol.
Throughout the procedure, it is essential to continuously monitor:
✔ the uniform distribution of the product;
✔ the amount applied to each area;
✔ the sequence of application;
✔ the contact time;
✔ the observed skin response;
✔ the level of comfort reported by the patient.
The application technique should always be adapted to the individual characteristics of the skin and should never be reproduced automatically for every patient.
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ORDER AND UNIFORMITY OF APPLICATION
Following a predefined sequence of application helps maintain precise control of the procedure and contributes to achieving a consistent exposure time across all treated areas.
It is recommended to:
✔ begin with the areas indicated in the professional treatment protocol;
✔ maintain a uniform amount of product;
✔ avoid product accumulation in skin folds or depressions;
✔ monitor proximity to mucous membranes and protected areas;
✔ continuously observe the response of each treated area.
A well-organised application technique makes it possible to adjust the procedure during the session whenever the clinical progression indicates that this is appropriate.
EXPOSURE TIME CONTROL
Exposure time is one of the most important variables of the procedure and should be determined according to the professional treatment protocol and the clinical progression observed during the session.
The practitioner should consider:
✔ the anatomical area being treated;
✔ the clinical characteristics of the skin;
✔ the patient’s tolerance;
✔ the skin response observed during application.
The maximum recommended exposure time should be regarded as a safety limit rather than a target that must necessarily be reached.
Whenever the clinical progression indicates, neutralisation should be carried out before the initially planned exposure time.
Under no circumstances should the exposure time be prolonged with the intention of obtaining a more intense response.
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CLINICAL OBSERVATION DURING THE SESSION
The skin response may vary between patients and even between different areas of the same patient.
For this reason, clinical observation should be maintained throughout the entire procedure.
The practitioner should pay particular attention to:
✔ the appearance of erythema;
✔ the sensation of warmth or stinging reported by the patient;
✔ the uniformity of the skin response;
✔ any differences between anatomical regions;
✔ any changes indicating that the procedure should be modified or discontinued.
The clinical progression observed should always take priority over the initial treatment plan.
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CRITERIA FOR COMPLETING THE APPLICATION
The application should be discontinued when:
✔ the expected clinical response has been achieved;
✔ the exposure time established in the treatment protocol has been completed;
✔ the patient experiences significant discomfort;
✔ an excessive or unexpected response is observed;
✔ the practitioner considers that continuing the procedure may increase the risk.
Completing the procedure at the appropriate time is an essential part of responsible clinical practice.
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NEUTRALISATION
Neutralisation is an essential stage of the procedure and should be carried out exclusively using the neutralising solution recommended by TherapDerma.
Its purpose is to stop the activity of the peel and allow precise control of the treatment intensity.
Once the neutralising solution has been applied, the practitioner should:
✔ ensure uniform coverage of the entire treated surface;
✔ pay particular attention to skin folds and areas where product accumulation may occur;
✔ completely remove the product in accordance with the established treatment protocol;
✔ immediately reassess the skin response before proceeding with the post-treatment care.
Neutralisation performed at the appropriate time is an essential element in ensuring the safety, uniformity and appropriate clinical progression of the procedure.
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IMMEDIATE AFTERCARE
Once neutralisation has been completed and the product has been completely removed, the next objective is to promote the restoration of skin comfort and support the physiological recovery process.
According to the observed skin response, the practitioner may apply the post-procedure products included in the TherapDerma protocol and recommend the most appropriate home care measures for the patient.
It is advisable to:
✔ use gentle cleansing products;
✔ apply the recommended skin-repair products;
✔ maintain appropriate skin hydration;
✔ use a broad-spectrum sunscreen every day;
✔ avoid direct sun exposure during the recovery period;
✔ temporarily discontinue potentially irritating cosmetic products;
✔ avoid exfoliants and other procedures until the skin has completely recovered;
✔ report any unexpected reactions.
Post-treatment care forms part of the treatment itself and contributes to promoting a progressive, controlled recovery that respects skin physiology.
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CLINICAL PROGRESSION AND FOLLOW-UP
Professional assessment does not end with the final application of the peel.
During the following days, clinical progression may vary between patients according to the individual characteristics of the skin and the response obtained during the treatment session.
During the follow-up assessment, the practitioner should evaluate:
✔ the progression of the skin;
✔ tolerance to the procedure;
✔ the physiological recovery of the epidermis;
✔ the presence or absence of desquamation;
✔ changes observed in skin texture and radiance;
✔ the need to adapt the home care routine;
✔ the appropriateness of scheduling a further treatment session.
Each treatment should be reassessed individually before continuing the therapeutic protocol.
GOOD PROFESSIONAL PRACTICE
The application of Malic Peel 15% should be integrated into an organised and standardised clinical methodology.
It is recommended to always adhere to the following principles:
✔ follow the TherapDerma professional treatment protocol;
✔ comply with the product’s technical instructions;
✔ adapt the procedure to each individual patient;
✔ continuously observe the clinical response;
✔ maintain constant communication with the patient;
✔ document each treatment session appropriately;
✔ reassess the patient before scheduling further procedures.
A systematic methodology and a precise application technique contribute to improving the safety, reproducibility and clinical consistency of every treatment.
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ERRORS TO AVOID
During the professional use of Malic Peel 15%, particular care should be taken to avoid:
✘ applying the same procedure identically to every patient;
✘ using an excessive amount of product;
✘ allowing product to accumulate in skin folds or sensitive areas;
✘ unnecessarily prolonging the exposure time;
✘ ignoring differences in the skin response between different anatomical regions;
✘ delaying neutralisation when the clinical progression indicates that the procedure should be completed;
✘ combining treatments without respecting the required recovery period;
✘ omitting home care recommendations;
✘ initiating further treatment sessions without prior clinical reassessment.
Preventing these errors forms part of responsible clinical practice and represents one of the principal factors in maintaining the safety of the procedure.
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PROFESSIONAL CHECKLIST
Before considering the procedure complete, confirm that:
☐ The peel was applied uniformly.
☐ The professional treatment protocol was followed.
☐ Neutralisation was carried out correctly.
☐ The product was completely removed.
☐ The immediate skin response was assessed.
☐ The indicated post-procedure care was applied.
☐ The patient received clear home care instructions.
☐ The treatment session was properly documented.
☐ A clinical follow-up appointment has been scheduled where appropriate.
A systematic verification at the end of every treatment session promotes continuity of care, facilitates clinical follow-up and contributes to maintaining high standards of professional quality.
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THERAPDERMA CONCLUSION
The correct application of a professional chemical peel requires far more than an appropriate technique. It demands careful planning, continuous clinical observation and the ability to adapt every decision to the skin’s individual response.
Malic Peel 15% has been developed for integration into structured professional treatment protocols, where every stage—from the initial preparation through to clinical follow-up—contributes to maintaining high standards of safety, technical precision and therapeutic consistency.
At TherapDerma, we believe that clinical excellence results from the combination of scientific knowledge, professional expertise and a rigorously planned methodology.
Within the TherapDerma Clinical Ecosystem™, Malic Peel 15% forms part of a model of patient care designed to optimise Skin Quality through personalised, reproducible procedures supported by scientific evidence, while always respecting skin physiology and each patient’s individual clinical progression.
Clinical Protocols
Personalised strategies for different therapeutic objectives
Malic Peel 15% may be incorporated into different aesthetic medicine programmes whenever there is an appropriate clinical indication and patient selection has been carried out correctly.
There is no single protocol that is suitable for every case. Treatment planning should be tailored to the biological characteristics of the skin, the established therapeutic objectives, and the clinical progress observed between sessions.
The protocols presented below are intended as general guidelines to support therapeutic planning and should always be applied in accordance with professional clinical judgement and TherapDerma’s official technical recommendations.
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SKIN REVITALISATION PROTOCOL
Objective
To promote physiological epidermal renewal aimed at progressively enhancing skin radiance, superficial hydration, and overall Skin Quality.
Suitable candidates
✔ Dull skin
✔ Loss of radiance
✔ Tired-looking complexion
✔ Irregular skin texture
✔ Early signs of skin ageing
✔ Devitalised skin
Clinical objectives
• Promote physiological epidermal renewal.
• Gradually enhance skin radiance.
• Improve superficial skin texture.
• Optimise Skin Quality.
Protocol progression
Continuation of treatment should be determined according to the clinical progress observed at each session, adapting the therapeutic strategy whenever necessary.
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HYDRATION AND SKIN QUALITY PROTOCOL
Objective
To optimise superficial hydration, promoting skin that is more comfortable, supple, radiant, and progressively improved in Skin Quality.
May be considered when presenting with
✔ Superficial dehydration
✔ Loss of elasticity
✔ Dull complexion
✔ Uneven skin texture
✔ Reduced skin quality
Clinical objectives
• Improve hydration of the stratum corneum.
• Promote greater skin comfort.
• Progressively optimise Skin Quality.
• Integrate the peel into professional Skin Quality programmes.
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SKIN TONE UNIFORMITY PROTOCOL
Objective
To promote a progressively more even-looking complexion through properly planned superficial epidermal renewal programmes.
May be considered when presenting with
✔ Superficial skin tone irregularities
✔ Loss of skin tone uniformity
✔ Early photoageing
✔ Reduced radiance
✔ Uneven skin texture
Clinical objectives
• Promote a visibly more even complexion.
• Progressively enhance skin radiance.
• Refine the epidermal microrelief.
• Complement advanced Skin Quality programmes.
Clinical progress should always be reassessed before modifying the therapeutic protocol.
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SKIN TEXTURE IMPROVEMENT PROTOCOL
Objective
To progressively improve the skin microrelief through physiological epidermal renewal aimed at enhancing skin texture and Skin Quality.
May be considered when presenting with
✔ Uneven skin texture
✔ Rough skin surface
✔ Loss of smoothness
✔ Early signs of skin ageing
✔ Dull skin
Clinical objectives
• Progressively refine skin texture.
• Promote a smoother and more even skin surface.
• Enhance skin radiance.
• Improve the overall visual quality of the skin.
Each treatment session should be reassessed before continuing the protocol to ensure that treatment remains aligned with the patient’s clinical progress.
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EARLY PHOTOAGEING PROTOCOL
Objective
To progressively improve skin radiance, texture, and visual uniformity through a superficial epidermal renewal programme that respects normal skin physiology.
May be considered when presenting with
✔ Loss of radiance
✔ Fine lines
✔ Uneven skin texture
✔ Uneven skin tone
✔ Early signs of photoageing
Clinical objectives
• Promote a more radiant complexion.
• Progressively improve skin texture.
• Optimise Skin Quality.
• Complement comprehensive skin rejuvenation programmes.
Treatment should always be integrated into a therapeutic strategy that includes daily photoprotection, appropriate home care, and regular clinical follow-up.
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FINE LINES PROTOCOL
Objective
To progressively improve the appearance of fine lines through physiological epidermal renewal programmes designed to revitalise the skin.
May be considered when presenting with
✔ Fine expression lines
✔ Reduced hydration
✔ Loss of radiance
✔ Early skin ageing
Clinical objectives
• Optimise Skin Quality.
• Promote a more even-looking complexion.
• Enhance skin revitalisation.
• Complement other professional skin rejuvenation protocols.
Treatment planning should always be adapted according to the patient’s clinical progress and individual needs.
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ADVANCED SKIN QUALITY PROTOCOL
Objective
To integrate Malic Peel 15% into a comprehensive programme designed to progressively optimise Skin Quality while respecting skin physiology and each patient’s individual clinical progression.
Target areas
✔ Hydration
✔ Radiance
✔ Texture
✔ Skin tone uniformity
✔ Revitalisation
✔ Skin Quality
Therapeutic integration
Where clinically indicated, Malic Peel 15% may be combined with:
✔ Mesotherapy
✔ PDRN
✔ Biostimulation protocols
✔ LED therapy
✔ Compatible medical-aesthetic technologies
✔ Professional home-care cosmetics
Combination treatments should always be carefully planned, respecting physiological recovery times and the clinical response observed between sessions.
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THERAPDERMA™ COMBINED PROTOCOLS
Integration within a comprehensive therapeutic strategy
Where clinically indicated, Malic Peel 15% may be incorporated into multidisciplinary treatment programmes designed to progressively optimise Skin Quality and enhance treatment outcomes through a comprehensive therapeutic approach.
Therapeutic options may include:
✔ Personalised mesotherapy
✔ PDRN protocols
✔ Biostimulation
✔ LED therapy
✔ Radiofrequency
✔ Compatible medical-aesthetic technologies
✔ Professional home-care cosmetics
Each procedure should always be selected according to a specific clinical objective while respecting skin physiology and the individual evolution of each patient.
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THERAPDERMA™ CLINICAL LADDER
Individualised treatment selection
The TherapDerma™ Clinical Ladder facilitates selection of the most appropriate therapeutic strategy according to the patient’s clinical needs and treatment progression.
Initial Level
Malic Peel 15%
May be considered when the objective is to:
✔ Revitalise the skin
✔ Enhance radiance
✔ Optimise superficial hydration
✔ Promote physiological epidermal renewal
✔ Develop Skin Quality programmes
Therapeutic progression should always be based on the patient’s clinical evolution and never on a predetermined sequence.
Every clinical decision should be supported by periodic reassessment and the established therapeutic objectives.
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MAINTENANCE PROTOCOL
Once the therapeutic objectives have been achieved, an individualised maintenance programme may be established according to each patient’s specific needs.
This programme may include:
✔ Periodic treatment sessions where clinically indicated
✔ Scheduled clinical reviews
✔ Updating the home-care skincare routine
✔ Incorporation of complementary procedures
✔ Daily photoprotection
✔ Ongoing Skin Quality programmes
Maintenance should always be individualised according to clinical progression, the biological characteristics of the skin, and the treatment objectives achieved.
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PROTOCOL PERSONALISATION
Every patient presents unique biological, functional, and clinical characteristics.
For this reason, therapeutic planning should be individualised at every session and adapted dynamically according to the clinical evolution observed.
Personalisation may involve adjusting:
✔ Treatment area
✔ Exposure time
✔ Product quantity
✔ Treatment sequence
✔ Session frequency
✔ Combination with complementary procedures
✔ Home-care recommendations
Protocol flexibility allows optimisation of the therapeutic response while maintaining clinical consistency and respecting normal skin physiology.
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CRITERIA FOR MODIFYING OR DISCONTINUING THE PROGRAMME
During follow-up, the therapeutic strategy may be modified whenever clinical evolution indicates that adjustments are appropriate.
Situations that may justify adapting the protocol include:
✔ Slower-than-expected recovery
✔ Prolonged skin sensitivity
✔ Insufficient therapeutic response
✔ Changes in medication or home-care routine
✔ Recent sun exposure
✔ Development of new clinical circumstances
✔ Achievement of the therapeutic objectives
Following appropriate clinical reassessment, the practitioner may:
• Continue with the original protocol.
• Increase the interval between sessions.
• Incorporate complementary procedures.
• Temporarily prioritise professional home-care cosmetics.
• Temporarily or permanently discontinue treatment.
Modifying, adapting, or concluding a treatment protocol when clinically appropriate represents a professional decision based on safety, individualisation, and scientific evidence.
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THERAPDERMA CONCLUSION
Clinical protocols provide a structured framework for treatment planning but should never replace professional clinical judgement or the individual assessment of each patient.
Malic Peel 15% enables the development of personalised programmes designed to enhance radiance, optimise skin texture, promote skin revitalisation, and integrate advanced Skin Quality strategies, with every protocol adapted according to the patient’s clinical progress.
Within the TherapDerma Clinical Ecosystem™, every treatment evolves through continuous clinical reassessment, therapeutic personalisation, and the integration of complementary procedures, enabling clinicians to deliver consistent, reproducible, safe, and evidence-based practice with progressive and long-lasting results.
Therapderma™ Combinations
Integrated protocols to enhance therapeutic planning
Modern aesthetic medicine is based on the strategic combination of different procedures, carefully selected and sequenced according to each patient’s clinical needs and therapeutic objectives.
Within this context, Malic Peel 15% may be incorporated as one phase of personalised treatment programmes designed to progressively optimise Skin Quality, revitalise the skin, and facilitate the integration of additional treatments whenever there is an appropriate clinical indication.
Each combination should address a specific therapeutic objective and be planned sequentially, respecting physiological recovery times and the clinical progression observed between procedures.
Within the TherapDerma Clinical Ecosystem™, Malic Peel 15% is a versatile solution that can be flexibly integrated with other professional treatments to develop fully personalised programmes.
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MALIC PEEL 15% + PERSONALISED MESOTHERAPY
Epidermal revitalisation and targeted treatment
Once physiological skin recovery has been completed, Malic Peel 15% may be integrated into personalised mesotherapy protocols whenever the clinical assessment determines that this combination is appropriate.
The selected formulation should always depend on the therapeutic objectives, the biological characteristics of the skin, and the individual needs of each patient.
Combination objectives
✔ Support personalised skin rejuvenation programmes.
✔ Enhance skin revitalisation.
✔ Progressively optimise Skin Quality.
✔ Improve hydration and radiance.
✔ Complement comprehensive Skin Quality strategies.
Mesotherapy should only be introduced once clinical progression confirms that the skin is fully prepared for the next stage of treatment.
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MALIC PEEL 15% + PDRN
Planned revitalisation and regeneration
When the therapeutic objective includes strategies designed to support the physiological processes of skin regeneration, Malic Peel 15% may form part of a sequential treatment plan that subsequently incorporates professional PDRN-based solutions.
The combination of both procedures should always be established within an individualised protocol following an appropriate clinical reassessment.
Combination objectives
✔ Support the physiological processes of skin regeneration.
✔ Progressively optimise Skin Quality.
✔ Complement personalised regenerative programmes.
✔ Integrate therapeutic strategies focused on skin recovery.
Each procedure should only be introduced after confirming favourable clinical progression and complete physiological skin recovery before proceeding to the next treatment phase.
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MALIC PEEL 15% + SKIN BIOSTIMULATION
Preparing the skin for a regenerative strategy
Biostimulation procedures may be incorporated into personalised programmes designed to progressively optimise Skin Quality and support an overall skin rejuvenation strategy.
Where clinically indicated, Malic Peel 15% may be used as a preparatory phase within a sequential therapeutic plan, facilitating the structured integration of complementary procedures.
Combination objectives
✔ Support structured therapeutic planning.
✔ Integrate complementary procedures sequentially.
✔ Develop personalised protocols tailored to the patient’s needs.
✔ Enhance physiological skin rejuvenation programmes.
Biostimulation techniques should only be introduced once skin recovery is complete and clinical reassessment confirms that the skin is ready for the next treatment phase.
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MALIC PEEL 15% + RADIOFREQUENCY
Superficial revitalisation and complementary technology
Radiofrequency may be incorporated, where clinically indicated, into treatment programmes designed to progressively optimise Skin Quality, improve the overall appearance of the skin, and complement skin rejuvenation protocols.
Following adequate physiological recovery, Malic Peel 15% may form part of a sequential therapeutic strategy combining both procedures in a carefully planned manner.
Combination objectives
✔ Enhance Skin Quality programmes.
✔ Support structured therapeutic planning.
✔ Integrate complementary medical-aesthetic technologies.
✔ Adapt treatment to the patient’s individual needs.
The sequence between both procedures should always respect physiological recovery times and the clinical evolution observed between sessions.
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MALIC PEEL 15% + LED THERAPY
Revitalisation and support during recovery
LED therapy may be incorporated as a complementary procedure within personalised protocols designed to support physiological skin recovery and optimise treatment continuity.
Its integration should always be based on a specific clinical indication and form part of a previously planned therapeutic strategy.
Combination objectives
✔ Support physiological skin recovery.
✔ Complement skin revitalisation protocols.
✔ Optimise clinical progression between treatment sessions.
✔ Integrate within comprehensive treatment programmes.
The LED protocol should always be individualised according to the patient’s clinical characteristics and therapeutic objectives.
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MALIC PEEL 15% + PROFESSIONAL HOME-CARE COSMETICS
Treatment continuity also takes place at home
The results of a professional treatment programme do not depend exclusively on the procedures performed in the clinic.
The home-care skincare routine is an essential component of therapeutic continuity, supporting the physiological evolution of the skin between sessions and contributing to the maintenance of treatment outcomes.
The home-care programme may include
✔ Appropriate cleansing products.
✔ Personalised professional skincare.
✔ Moisturising products.
✔ Antioxidants where clinically indicated.
✔ Active ingredients selected according to the therapeutic objectives.
✔ Daily broad-spectrum photoprotection.
Each product should be individually selected according to the biological characteristics of the skin, clinical progression, and the specific needs of each patient.
Adherence to the prescribed home-care programme is fundamental for maintaining therapeutic continuity and supporting the progressive improvement of Skin Quality.
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THERAPDERMA CLINICAL ECOSYSTEM™
A therapeutic approach based on integration
At TherapDerma, we believe that the best clinical outcomes do not depend on a single procedure, but on the correct planning and integration of every stage of treatment.
Each intervention forms part of a comprehensive therapeutic strategy in which diagnosis, clinical procedures, recovery, follow-up, and home care work together in a coordinated manner to meet each patient’s individual needs.
Example of an integrated treatment pathway
Clinical Diagnosis
↓
Definition of Therapeutic Objectives
↓
Malic Peel 15%
↓
Recovery and Clinical Reassessment
↓
Mesotherapy · PDRN · Biostimulation (where clinically indicated)
↓
Complementary Medical-Aesthetic Technology
↓
Professional Home-Care Cosmetics
↓
Clinical Follow-up
↓
Personalised Maintenance Programme
Every stage should be individualised according to clinical progression, skin response, and the established therapeutic objectives.
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BENEFITS OF INTEGRATED PROTOCOLS
Integrating Malic Peel 15% into personalised therapeutic programmes enables clinicians to develop more structured, progressive, and patient-specific treatment strategies.
Key benefits include
✔ Facilitating therapeutic planning.
✔ Integrating different procedures within a coherent clinical strategy.
✔ Enhancing skin revitalisation and Skin Quality.
✔ Preparing the skin for subsequent treatment phases.
✔ Organising the correct sequence between procedures.
✔ Adapting each stage according to clinical progression.
✔ Supporting continuity of patient care.
✔ Improving coordination between in-clinic treatments and home-care programmes.
The combination of procedures should always respond to clearly defined therapeutic objectives and form part of a fully individualised treatment plan.
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CLINICAL SUMMARY
Clinical Objective Recommended Combination
Personalised revitalisation Malic Peel 15% + Personalised Mesotherapy
Skin regeneration Malic Peel 15% + PDRN
Biostimulation programmes Malic Peel 15% + Skin Biostimulation
Technology integration Malic Peel 15% + Radiofrequency
Recovery and therapeutic support Malic Peel 15% + LED Therapy
Continuity between sessions Malic Peel 15% + Professional Home-Care Cosmetics
All combinations should be planned sequentially, respecting physiological recovery times and adapting to each patient’s clinical progression.
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THERAPDERMA PHILOSOPHY
A clinical strategy, not simply a collection of procedures
At TherapDerma, we believe that every treatment forms part of a much broader therapeutic process.
True clinical value lies not only in each individual procedure but in the way every stage of treatment is integrated to address the specific needs of each patient with precision.
This philosophy enables the development of therapeutic programmes that are more structured, personalised, and aligned with clinical progression, promoting continuity of care, improved coordination between procedures, and treatment planning based on scientific principles.
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THERAPDERMA CONCLUSION
The intelligent combination of procedures is one of the fundamental pillars of modern aesthetic medicine. Its success depends on appropriate planning, correct sequencing of every treatment phase, and the ability to adapt the therapeutic strategy according to each patient’s clinical progression.
Malic Peel 15% represents a versatile solution within the TherapDerma Clinical Ecosystem™, capable of being progressively integrated with other professional treatments whenever clinically indicated and always under professional clinical judgement.
Its integration with mesotherapy, PDRN, biostimulation, medical-aesthetic technologies, and professional home-care cosmetics enables the development of programmes designed to optimise Skin Quality, enhance skin revitalisation, and maintain therapeutic continuity through personalised, coherent, and reproducible protocols.
At TherapDerma, we believe that clinical excellence is achieved when scientific knowledge, therapeutic planning, continuous clinical reassessment, and treatment individualisation work together, enabling safer, more effective aesthetic medicine that respects normal skin physiology and addresses the genuine needs of every patient.
Frequently Asked Questions (FAQ)
Clear answers to support clinical practice
During the planning and performance of a professional chemical peel, questions commonly arise regarding patient selection, treatment planning, and the integration of the procedure into personalised treatment protocols.
The following questions address some of the most frequently raised enquiries by professionals during clinical practice and TherapDerma training programmes.
Their purpose is to support clinical decision-making and complement the information provided in this catalogue, without replacing individual clinical assessment or the official technical instructions for the product.
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WHAT TYPE OF PEEL IS MALIC PEEL 15%?
Malic Peel 15% is a professional superficial chemical peel formulated with 15% Malic Acid, belonging to the Alpha Hydroxy Acid (AHA) family.
It has been developed to promote progressive epidermal renewal while respecting normal skin physiology and contributing to improved superficial hydration, skin radiance, and overall Skin Quality.
Within individualised treatment protocols, it may be incorporated to progressively enhance:
✔ Skin radiance
✔ Superficial hydration
✔ Skin texture
✔ Skin tone uniformity
✔ Skin Quality
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WHICH PATIENTS MAY BE SUITABLE CANDIDATES?
Malic Peel 15% may be considered when clinical assessment identifies characteristics consistent with skin revitalisation and physiological epidermal renewal programmes.
It may commonly be considered in patients presenting with:
✔ Dull or devitalised skin
✔ Loss of radiance
✔ Superficial dehydration
✔ Uneven skin texture
✔ Fine expression lines
✔ Early signs of photoageing
The final indication should always depend on the clinical diagnosis, the functional condition of the skin, and the therapeutic objectives established for each patient.
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WHAT IS THE DIFFERENCE BETWEEN MALIC ACID AND OTHER ALPHA HYDROXY ACIDS?
All Alpha Hydroxy Acids share a general mechanism of epidermal renewal; however, each possesses its own physicochemical properties and clinical profile.
The outcome of a chemical peel does not depend solely on the type of acid used.
Other important factors include:
✔ Concentration
✔ pH
✔ Vehicle
✔ Exposure time
✔ Application technique
✔ Functional condition of the skin
For this reason, peel selection should always be based on clinical diagnosis and the therapeutic objectives established for each patient.
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CAN IT BE USED ON SENSITIVE SKIN?
Malic Peel 15% has been designed to promote progressive epidermal renewal while respecting normal skin physiology.
Nevertheless, even in patients with sensitive skin, treatment should always be based on an individual clinical assessment.
Before commencing treatment, it is advisable to evaluate:
✔ Skin sensitivity
✔ Presence of erythema
✔ History of intolerance
✔ Recently performed procedures
✔ Home-care cosmetic products currently in use
Appropriate patient selection and correct protocol planning remain the primary safety factors.
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HOW MANY SESSIONS ARE USUALLY RECOMMENDED?
There is no fixed number of treatment sessions suitable for every patient.
The duration of the treatment programme depends on several clinical factors, including:
✔ Initial diagnosis
✔ Therapeutic objectives
✔ Clinical response after each session
✔ Skin recovery capacity
✔ Overall clinical progression
Each session should form part of an individualised therapeutic strategy and should only be scheduled following appropriate professional reassessment.
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HOW OFTEN CAN THE TREATMENT BE PERFORMED?
The interval between treatment sessions should always be individualised according to each patient’s clinical progression.
Before scheduling a further application, it is essential to confirm that the skin has adequately recovered its normal physiological condition.
When determining the most appropriate interval, the following should be considered:
✔ Observed skin response
✔ Degree of recovery
✔ Intensity of the previous protocol
✔ Treatment area
✔ Integration with other procedures
A new session should not be initiated while signs of irritation or incomplete recovery persist.
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CAN IT BE COMBINED WITH OTHER PROCEDURES?
Yes.
Malic Peel 15% may be incorporated into personalised therapeutic programmes whenever there is an appropriate clinical indication.
Depending on the treatment objectives, it may be combined sequentially with procedures such as:
✔ Personalised mesotherapy
✔ Professional PDRN solutions
✔ Biostimulation protocols
✔ Radiofrequency
✔ LED therapy
✔ Professional home-care cosmetics
✔ Other compatible medical-aesthetic technologies
Combination treatments should always be planned while respecting physiological recovery times.
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IS NEUTRALISATION REQUIRED?
Yes.
Malic Peel 15% requires neutralisation at the end of the prescribed application time or earlier if the clinical response indicates that this is appropriate.
Neutralisation should only be performed using the TherapDerma neutralising solution and in accordance with the official technical protocol.
Once the procedure has been completed, complete removal of the product should be confirmed before initiating post-treatment care.
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WHAT AFTERCARE SHOULD THE PATIENT FOLLOW?
Post-treatment care forms an essential part of the overall treatment programme and contributes to appropriate skin recovery between sessions.
Following each procedure, the practitioner may recommend a personalised home-care programme, which may include:
✔ Gentle cleansing products
✔ Personalised professional skincare
✔ Moisturising products
✔ Daily broad-spectrum photoprotection
✔ Temporary discontinuation of potentially irritating products
✔ Avoidance of additional procedures until full recovery has been achieved
Following these recommendations contributes to maintaining treatment continuity.
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CAN IT BE USED ALL YEAR ROUND?
The suitability of performing a chemical peel does not depend solely on the season of the year, but rather on clinical assessment and each patient’s individual circumstances.
Before planning treatment, the following should be evaluated:
✔ Skin phototype
✔ Anticipated sun exposure
✔ Individual risk of pigmentary alterations
✔ Treatment area
✔ Patient compliance with adequate photoprotection
Where circumstances may compromise physiological skin recovery, it may be advisable to modify the treatment protocol or temporarily postpone the procedure.
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CAN IT FORM PART OF SKIN REJUVENATION PROGRAMMES?
Yes.
Where clinically indicated, Malic Peel 15% may be incorporated into personalised programmes designed to progressively optimise Skin Quality.
Within these protocols it may contribute to:
✔ A more radiant complexion
✔ Improved skin texture
✔ Better superficial hydration
✔ Enhanced Skin Quality
Like any professional procedure, it should always form part of a comprehensive therapeutic strategy that includes photoprotection, appropriate home care, and additional treatments whenever clinically indicated.
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WHAT IS THE MAIN OBJECTIVE OF MALIC PEEL 15%?
The primary objective of Malic Peel 15% is to promote progressive epidermal renewal aimed at revitalising the skin and optimising Skin Quality.
Its use may contribute to:
✔ Improving skin radiance
✔ Optimising superficial hydration
✔ Refining skin texture
✔ Promoting a more even-looking complexion
✔ Complementing professional Skin Quality programmes
Treatment planning should always be adapted to the individual needs of each patient.
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QUICK SUMMARY
Key concepts about Malic Peel 15%
✔ Professional superficial chemical peel containing 15% Malic Acid.
✔ Progressive epidermal renewal.
✔ Supports skin revitalisation and superficial hydration.
✔ Contributes to improved radiance and skin texture.
✔ Suitable only following an individual clinical assessment.
✔ Can be integrated into personalised TherapDerma Clinical Ecosystem™ protocols.
✔ Compatible with sequential therapeutic strategies where professionally indicated.
✔ Mandatory neutralisation in accordance with the official technical protocol.
✔ Treatment planning, clinical follow-up, and continuous reassessment are essential components of the therapeutic programme.
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THERAPDERMA CONCLUSION
The Frequently Asked Questions section serves as a practical reference designed to support everyday clinical practice and address the most common questions regarding the use of Malic Peel 15%.
Beyond the formulation itself, the success of a chemical peel depends on appropriate patient selection, individualised treatment planning, meticulous application technique, and continuous monitoring of clinical progress.
Within the TherapDerma Clinical Ecosystem™, Malic Peel 15% is integrated as a therapeutic solution designed to support personalised skin revitalisation programmes, optimise Skin Quality, and promote physiological skin rejuvenation, always based on objective clinical criteria.
Our commitment is to provide solutions supported by scientific knowledge, promoting responsible, personalised aesthetic medicine focused on achieving progressive, reproducible, and physiologically respectful clinical outcomes.
Related Content
Discover the TherapDerma Professional Universe
Modern aesthetic medicine requires a comprehensive approach that combines scientific knowledge, clinical planning, and continuous professional development.
For this reason, Malic Peel 15% forms part of the TherapDerma Clinical Ecosystem™, a professional environment that integrates scientific resources, clinical protocols, technologies, educational programmes, and complementary solutions designed to support practitioners throughout every stage of clinical practice.
In addition to this catalogue, TherapDerma provides a comprehensive collection of guides, protocols, and professional resources that enable clinicians to develop personalised, structured, and evidence-based treatment programmes.
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THERAPDERMA PEELING COLLECTION™
A collection designed for different clinical objectives
The TherapDerma Peeling Collection™ brings together a range of professional peeling solutions, allowing practitioners to select the most appropriate acid and concentration according to each patient’s clinical characteristics.
The collection includes different formulations developed to address a wide variety of therapeutic needs while maintaining a common philosophy based on treatment personalisation.
Available Collection
✔ Glycolic Peel
✔ Lactic Peel
✔ Malic Peel
✔ Mandelic Peel
✔ Salicylic Peel
✔ Pyruvic Peel
✔ TCA Peel
Each formulation has been developed for integration into professional treatment protocols tailored to different clinical indications.
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THERAPDERMA MESOTHERAPY COLLECTION™
Professional solutions for personalised treatment protocols
The TherapDerma Mesotherapy Collection™ comprises formulations developed to complement aesthetic medicine programmes tailored to the individual needs of each patient.
The range includes professional solutions designed for different treatment areas, including:
✔ Skin revitalisation
✔ Professional hydration
✔ Skin rejuvenation programmes
✔ Biostimulation
✔ Skin regeneration
✔ Body treatment protocols
✔ Hair restoration treatments
Each formulation forms part of a personalised therapeutic approach and may be integrated into clinical strategies designed by the practitioner.
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THERAPDERMA TECHNOLOGIES™
Technology supporting clinical practice
TherapDerma medical-aesthetic technologies have been carefully selected to expand therapeutic possibilities and complement a wide variety of treatment programmes.
The collection includes devices intended for different clinical applications, enabling practitioners to develop protocols tailored to each patient’s therapeutic objectives.
The combined use of professional technologies and clinical procedures supports a more versatile, structured, and personalised approach to aesthetic medicine.
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THERAPDERMA CLINICAL PROTOCOLS™
Protocols developed to support clinical planning
TherapDerma provides structured clinical protocols that serve as practical guides for organising a wide range of professional treatments.
These documents provide a clear methodology for therapeutic planning, promoting procedural standardisation while maintaining the essential flexibility required for personalised patient care.
The protocols are intended as professional guidance and should always be adapted according to clinical judgement and each patient’s individual characteristics.
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THERAPDERMA SKINCARE™
Professional skincare to support every treatment
The TherapDerma Skincare™ range has been developed to complement in-clinic procedures through personalised home-care programmes adapted to different skin needs.
The collection includes professional solutions designed to support treatment progression and maintain continuity of care between clinical sessions.
Its principal categories include:
✔ Professional cleansing
✔ Hydration
✔ Skin barrier repair
✔ Antioxidant care
✔ Pigmentation management
✔ Photoprotection
✔ Skin Quality maintenance
Every home-care programme should be individually tailored according to the characteristics and therapeutic objectives of each patient.
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THERAPDERMA PROFESSIONAL EDUCATION™
Scientific education for professionals
Continuous professional development is one of the fundamental pillars of modern aesthetic medicine.
Through TherapDerma Professional Education™, practitioners have access to educational programmes designed to expand their clinical knowledge and remain up to date with the latest scientific developments within the sector.
Training activities include:
✔ Specialised courses
✔ Clinical masterclasses
✔ Practical workshops
✔ Treatment protocols
✔ Clinical case studies
✔ Scientific updates
✔ Training in new technologies and procedures
Our objective is to provide educational resources that support professional development and promote evidence-based clinical practice.
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THERAPDERMA CLINICAL ECOSYSTEM™
An ecosystem designed for clinical practice
All resources developed by TherapDerma form part of a unified clinical philosophy, in which every tool complements the others and contributes to a comprehensive approach to patient treatment.
TherapDerma Clinical Ecosystem
Clinical Assessment
↓
Therapeutic Planning
↓
Professional Procedure
↓
Complementary Treatments
↓
Home Care
↓
Clinical Follow-up
↓
Maintenance Programme
This framework represents a recommended model for clinical treatment planning and should always be adapted according to professional clinical judgement and the specific needs of each patient.
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RECOMMENDED RESOURCES
To further expand your knowledge and explore the different TherapDerma programmes, we recommend consulting:
✔ TherapDerma™ Complete Peeling Catalogue
✔ TherapDerma Mesotherapy Collection™
✔ TherapDerma™ Clinical Protocols Manual
✔ TherapDerma Clinical Decision Guide™
✔ TherapDerma Professional Education™
✔ Clinical Combination Guide
✔ TherapDerma™ Professional Skincare Guide
Each of these resources has been developed to provide practical information and facilitate the planning of personalised treatment programmes within professional aesthetic medicine.
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THERAPDERMA CONCLUSION
Scientific knowledge forms the foundation of responsible clinical practice.
For this reason, Malic Peel 15% is not presented as an isolated procedure, but as an integral component of the TherapDerma Clinical Ecosystem™—a professional environment that combines scientific resources, continuing education, clinical protocols, technologies, and complementary solutions designed to support practitioners in their daily clinical practice.
Through the TherapDerma Clinical Ecosystem™, we provide a comprehensive collection of professional resources aimed at facilitating therapeutic planning, supporting continuous scientific development, and promoting personalised, consistent, and evidence-based aesthetic medicine.
Our commitment is to support practitioners beyond the procedure itself by providing solutions that contribute to the continuous advancement of clinical knowledge and to responsible, safe medical practice focused on achieving reproducible results while respecting normal skin physiology.
Therapderma Professional Academy™
Where Knowledge Becomes Clinical Excellence
Aesthetic medicine is constantly evolving. New scientific knowledge, technologies, and procedures make continuous professional development essential in order to deliver clinical practice that is increasingly evidence-based and adapted to patients’ needs.
With this vision, TherapDerma Professional Academy™ was created—an international educational platform designed to support doctors, nurses, pharmacists, dentists, and other aesthetic medicine professionals, always within the legal and professional framework applicable in each country.
Beyond simply providing information, our mission is to help practitioners develop sound clinical judgement, strengthen their analytical skills, and transform scientific knowledge into responsible therapeutic decision-making.
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OUR MISSION
Training professionals, not simply teaching procedures
At TherapDerma, we believe that true professional excellence does not depend solely on understanding a product or mastering a particular technique.
Above all, it depends on the ability to interpret scientific evidence, analyse each clinical situation, and select the most appropriate therapeutic strategy for every patient.
For this reason, our Academy has been developed to promote education based on critical thinking, continuous learning, and long-term professional development.
Our purpose is to help practitioners:
✔ Understand the scientific foundations of aesthetic medicine.
✔ Develop a broader clinical perspective.
✔ Strengthen professional clinical reasoning.
✔ Make evidence-based therapeutic decisions.
✔ Integrate scientific knowledge into everyday clinical practice.
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OUR EDUCATIONAL MODEL
Learning to think clinically
Education achieves its true value when it enables practitioners to interpret clinical situations more effectively and make decisions with greater confidence and sound judgement.
For this reason, the methodology of TherapDerma Professional Academy™ is based on a continuous learning process designed to promote long-term professional development.
Our Learning Philosophy
Learn
↓
Understand
↓
Analyse
↓
Decide
↓
Apply
↓
Evaluate
↓
Continue Learning
This model transforms education into a dynamic process of continuous improvement, where every new piece of knowledge contributes to professional growth and a more reflective approach to clinical practice.
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TRAINING AREAS
Multidisciplinary knowledge for modern aesthetic medicine
The educational programmes developed by TherapDerma Professional Academy™ cover a wide range of subjects related to professional clinical practice, providing a comprehensive understanding of aesthetic medicine.
Core training areas include:
✔ Professional chemical peels
✔ Mesotherapy
✔ Biostimulation
✔ PDRN
✔ Medical-aesthetic technologies
✔ Skin Quality
✔ Professional skincare
✔ Clinical protocols
✔ Clinical case studies
✔ Clinical documentation
✔ Patient communication
✔ Scientific updates
Each programme has been designed to complement the practitioner’s experience while promoting progressive, structured learning that reflects the latest advances within the sector.
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LEARNING FORMATS
Education tailored to different professional profiles
Every practitioner has different needs, objectives, and learning preferences. For this reason, TherapDerma Professional Academy™ offers educational programmes in a variety of formats, providing flexible access to knowledge throughout every stage of professional development.
Available formats may include:
✔ Face-to-face training
✔ Online learning
✔ Scientific webinars
✔ Practical workshops
✔ Specialist masterclasses
✔ Professional congresses and meetings
✔ Clinical case reviews
✔ Scientific update programmes
All programmes share a common objective: to promote continuous, practical education aligned with the ongoing evolution of aesthetic medicine.
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WHAT MAKES THERAPDERMA PROFESSIONAL ACADEMY™ DIFFERENT?
We do more than teach procedures—we develop clinical judgement
At TherapDerma, we recognise that learning a technique represents only one aspect of professional development.
Our educational philosophy is centred on preparing practitioners to interpret scientific evidence, analyse each clinical situation, and make well-informed therapeutic decisions.
Our Approach to Education
We do not simply teach products.
We teach the scientific principles behind them.
We do not simply teach protocols.
We teach how to build therapeutic strategies.
We do not simply teach techniques.
We teach the development of sound clinical judgement.
We do not simply teach treatments.
We teach how to individualise every clinical decision.
We do not simply teach innovation.
We teach how to interpret scientific evidence and apply it responsibly.
We believe that knowledge acquires its greatest value when it enables practitioners to make better decisions for the benefit of every patient.
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THERAPDERMA PHILOSOPHY
Knowledge as the driving force behind professional excellence
Innovation evolves continuously.
Products change.
Technologies advance.
Trends develop.
However, scientific knowledge and clinical reasoning remain the foundations upon which high-quality professional practice is built.
For this reason, TherapDerma Professional Academy™ promotes a culture of lifelong learning, where every educational programme represents an opportunity to expand knowledge, refine professional skills, and continue evolving as a clinician.
Our commitment is to support practitioners throughout their professional journey by providing resources that promote increasingly safe, structured, and evidence-based clinical practice.
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THERAPDERMA CONCLUSION
TherapDerma Professional Academy™ represents one of the fundamental pillars of the TherapDerma Clinical Ecosystem™, integrating scientific education, professional development, and continuous learning within a single educational philosophy.
We believe that clinical excellence begins long before the first procedure. It begins with a practitioner who embraces lifelong learning, critically evaluates scientific evidence, and adapts every clinical decision to the individual needs of each patient.
Beyond delivering educational programmes, our mission is to contribute to the growth of a community of professionals committed to ethical, personalised, and knowledge-driven aesthetic medicine.
Because the best treatment begins long before the first procedure.
It begins with a practitioner who is prepared to make the right decision.
Therapderma Clinical Decision System™
Transforming Scientific Knowledge into Clinical Decision-Making
Modern aesthetic medicine requires far more than simply understanding the characteristics of a product.
Every patient presents unique biological needs, expectations, and recovery capabilities. For this reason, treatment selection should never rely solely on personal experience or the automatic application of standardised protocols.
The TherapDerma Clinical Decision System™ (TCDS™) has been developed as a structured clinical reasoning framework designed to help practitioners transform information gathered during clinical assessment into individualised, scientifically supported treatment decisions.
Its purpose is to facilitate:
✔ Clinical assessment
✔ Identification of indications and contraindications
✔ Definition of realistic therapeutic objectives
✔ Selection of the appropriate procedure
✔ Individualised treatment planning
✔ Clinical observation and reassessment
✔ Clinical documentation
✔ Continuity of patient care
The system does not replace professional clinical judgement or the official technical instructions for each product.
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STEP 1
CLINICAL ASSESSMENT AND DIAGNOSIS
Every treatment protocol begins with a comprehensive patient assessment.
Before selecting a chemical peel, the practitioner should identify the skin’s needs and any factors that may influence its biological response.
The assessment may include:
✔ Reason for consultation
✔ Patient expectations
✔ Medical and dermatological history
✔ Current medication
✔ Known allergies
✔ Previous medical and aesthetic treatments
✔ Skin type and functional characteristics
✔ Sebaceous activity
✔ Condition of the stratum corneum
✔ Integrity of the skin barrier function
✔ Skin sensitivity and reactivity
✔ Skin phototype
✔ Presence of lesions, irritation, or inflammation
✔ Home-care skincare routine
✔ Lifestyle and sun exposure
✔ Ability to comply with post-treatment care
A thorough assessment enables the practitioner to identify appropriate indications, detect potential contraindications, and establish a treatment plan tailored to each patient’s individual characteristics and needs.
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STEP 2
IDENTIFYING THE CLINICAL OBJECTIVE
Following the initial assessment, the primary therapeutic objective should be clearly defined.
For patients who may be suitable candidates for Malic Peel 15%, objectives may include:
✔ Promoting progressive epidermal renewal
✔ Improving superficial hydration
✔ Enhancing skin radiance
✔ Improving superficial skin texture
✔ Promoting a more even-looking skin tone
✔ Progressively optimising Skin Quality
✔ Supporting skin revitalisation programmes
✔ Sequentially preparing the skin for additional procedures where clinically indicated
✔ Maintaining Skin Quality within individualised treatment programmes
Clearly defining the therapeutic objective enables the practitioner to select the most appropriate procedure and establish realistic patient expectations.
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STEP 3
PEEL SELECTION
The practitioner should determine whether Malic Peel 15% is an appropriate option for the individual patient.
The decision should consider:
✔ Sebaceous activity
✔ Skin sensitivity and reactivity
✔ Integrity of the skin barrier
✔ Thickness and functional condition of the stratum corneum
✔ Presence of uneven skin texture
✔ Loss of radiance
✔ Superficial skin tone irregularities
✔ Superficial dehydration
✔ Previous experience with chemical peels
✔ Response to previous treatments
✔ Recovery capacity
✔ Established therapeutic objectives
✔ Ability to comply with post-treatment care
Malic Peel 15% may be considered when the objective is to promote progressive epidermal renewal in appropriately selected patients.
The final indication should always be based on an individual clinical assessment.
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STEP 4
PROTOCOL PERSONALISATION
The peel concentration represents only one of the factors influencing the skin’s response.
The treatment protocol should be personalised by considering:
✔ Skin preparation
✔ Cleansing and degreasing where indicated
✔ Quantity of product
✔ Number of layers
✔ Extent of the treatment area
✔ Exposure time
✔ Application technique
✔ Clinical observation during the procedure
✔ Mandatory neutralisation
✔ Complete product removal
✔ Post-treatment care
✔ Home-care skincare
✔ Recovery intervals
✔ Session frequency
✔ Integration with complementary procedures
✔ Response observed during previous sessions
Personalisation enables the procedure to be adapted to the functional characteristics of the skin while reducing avoidable risks.
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STEP 5
PROFESSIONAL APPLICATION
Application should always follow the official technical protocol for TherapDerma Malic Peel 15%.
During the procedure, the practitioner should monitor:
✔ Appropriate preparation of the treatment area
✔ Product quantity and distribution
✔ Number of layers
✔ Exposure time
✔ Patient comfort
✔ Clinical signs observed
✔ The need for earlier neutralisation if clinically indicated
✔ Uniform neutralisation
✔ Complete removal of the product
Patient safety and the observed skin response should always take priority over strict adherence to a predetermined application time.
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STEP 6
RECOVERY AND INTEGRATION OF COMPLEMENTARY PROCEDURES
Following the peel, sufficient time should be allowed for physiological skin recovery.
Before introducing any additional procedure, the practitioner should confirm:
✔ Recovery of skin barrier function
✔ Absence of persistent irritation
✔ Resolution of significant desquamation
✔ Absence of unexpected reactions
✔ Compliance with home-care recommendations
✔ Clinical suitability for the next intervention
Where clinically indicated, subsequent procedures may include:
✔ Personalised mesotherapy
✔ Professional PDRN solutions
✔ Biostimulation
✔ Medical-aesthetic technologies
✔ Radiofrequency
✔ LED therapy
✔ Professional home-care cosmetics
Combination treatments should never be performed automatically or necessarily during the same session.
Treatment sequencing and intervals should always respect the characteristics of each procedure and the patient’s biological response.
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STEP 7
CLINICAL FOLLOW-UP AND REASSESSMENT
Clinical decision-making continues after every treatment session.
Follow-up enables evaluation of:
✔ Recovery of skin barrier function
✔ Treatment tolerance
✔ Occurrence of unexpected reactions
✔ Changes in superficial skin texture
✔ Changes in skin radiance
✔ Changes in skin tone uniformity
✔ Evolution of Skin Quality
✔ Compliance with home-care recommendations
✔ Patient perception and satisfaction
✔ The need to continue, modify, postpone, or discontinue the treatment protocol
Each review provides valuable information for adapting subsequent stages of treatment.
Continuation of the programme should never be considered automatic.
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STEP 8
CLINICAL DOCUMENTATION
Every procedure should be appropriately documented.
Clinical records may include:
✔ Initial assessment
✔ Clinical indication
✔ Excluded contraindications
✔ Informed consent
✔ Product and concentration used
✔ Batch number and expiry date, where applicable
✔ Treatment area
✔ Skin preparation
✔ Number of layers
✔ Exposure time
✔ Observed clinical response
✔ Timing and method of neutralisation
✔ Recommended post-treatment care
✔ Incidents or adverse events
✔ Follow-up date
✔ Protocol modifications
Comprehensive documentation promotes traceability and supports continuity of patient care.
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THERAPDERMA™ ALGORITHM
From Clinical Assessment to Clinical Decision
Clinical Assessment
↓
Identification of Indications and Contraindications
↓
Definition of the Clinical Objective
↓
Peel Selection
↓
Protocol Personalisation
↓
Professional Application
↓
Mandatory Neutralisation
↓
Post-Treatment Care
↓
Recovery and Clinical Reassessment
↓
Potential Integration of Complementary Procedures
↓
Follow-up and Documentation
↓
Individualised Maintenance
This algorithm provides a recommended framework for the TherapDerma Clinical Decision System™.
It does not represent a universal treatment protocol.
Every stage should be adapted according to the clinical diagnosis, the practitioner’s professional scope of practice, the official product instructions, and the patient’s individual clinical progression.
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BENEFITS OF THE THERAPDERMA CLINICAL DECISION SYSTEM™
Using a structured decision-making model may help practitioners to:
✔ Organise the clinical assessment
✔ Recognise indications and contraindications
✔ Define realistic therapeutic objectives
✔ Select procedures based on sound clinical reasoning
✔ Individualise every treatment protocol
✔ Improve observation during treatment
✔ Integrate mandatory neutralisation and post-treatment care
✔ Promote safer clinical practice
✔ Improve communication with patients
✔ Support continuity of patient care
✔ Reduce automatic or insufficiently justified decisions
✔ Document and reassess every stage
✔ Adapt treatment according to the observed clinical response
Organised clinical knowledge supports decisions that are better aligned with each patient’s biological characteristics.
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TCDS™ PHILOSOPHY
At TherapDerma, we believe that no single product is the appropriate solution for every patient.
The value of clinical reasoning lies in understanding:
✔ When a treatment may be appropriate
✔ When it should not be used
✔ Which patient is suitable
✔ What therapeutic objective is being pursued
✔ Which technique should be employed
✔ Within which treatment sequence
✔ Which post-treatment care is required
✔ When the protocol should be modified or discontinued
The TherapDerma Clinical Decision System™ does not replace professional judgement, education, responsibility, or the legal framework governing clinical practice.
Instead, it provides a methodology based on:
✔ Assessment
✔ Diagnosis
✔ Selection
✔ Personalisation
✔ Clinical observation
✔ Neutralisation
✔ Follow-up
✔ Documentation
✔ Reassessment
Every decision should be based on skin physiology and functional condition rather than solely on the technical or commercial characteristics of the product.
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THERAPDERMA CONCLUSION
The TherapDerma Clinical Decision System™ provides a structured framework to support clinical assessment, treatment selection, and therapeutic planning within aesthetic medicine.
Rather than offering rigid protocols, it organises clinical reasoning and facilitates the transformation of scientific knowledge into individualised, evidence-based clinical decisions.
Integrated within the TherapDerma Clinical Ecosystem™, it enables Malic Peel 15% to be incorporated into a comprehensive therapeutic strategy that includes:
✔ Clinical diagnosis
✔ Appropriate patient selection
✔ Protocol personalisation
✔ Controlled application
✔ Mandatory neutralisation
✔ Skin recovery
✔ Clinical follow-up
✔ Documentation
✔ Continuity of patient care
This approach may contribute to progressive epidermal renewal, gradual improvement of superficial hydration, enhanced skin radiance, and optimised Skin Quality whenever clinically indicated.
Every decision, every procedure, and every stage of treatment should be adapted to the individual patient’s needs, tolerance, recovery capacity, and biological progression.
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