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Glycolic Peel 50%

Glycolic Peel 50% Intensive epidermal renewal for advanced aesthetic medicine protocols TherapDerma Glycolic Peel 50% is a professional chemical peel formulated with 50% Glycolic Acid, belonging to the Alpha Hydroxy Acid (AHA) family, developed to provide a high-intensity superficial-to-medium chemical exfoliation and promote more active epidermal renewal within carefully planned clinical protocols. This concentration represents a higher level within the TherapDerma glycolic peel range and is intended for professionals who wish to increase epidermal renewal capacity in appropriately selected patients with adequate tolerance to previous treatments. Thanks to its low molecular weight, Glycolic Acid diffuses very efficiently through the stratum corneum, promoting homogeneous exfoliation that helps improve the superficial quality of the skin, optimise its texture and restore a more even, radiant and revitalised appearance. More than a standalone peel, Glycolic Peel 50% forms part of the TherapDerma Clinical Ecosystem™, a working model based on progressive protocols integrating chemical peels, mesotherapy, medical-aesthetic technologies and home care to achieve reproducible, safe and cumulative results.

Description

Glycolic Peel 50%
Intensive epidermal renewal for advanced aesthetic medicine protocols
TherapDerma Glycolic Peel 50% is a professional chemical peel formulated with 50% Glycolic Acid, belonging to the Alpha Hydroxy Acid (AHA) family, developed to provide a high-intensity superficial-to-medium chemical exfoliation and promote more active epidermal renewal within carefully planned clinical protocols.
This concentration represents a higher level within the TherapDerma glycolic peel range and is intended for professionals who wish to increase epidermal renewal capacity in appropriately selected patients with adequate tolerance to previous treatments.
Thanks to its low molecular weight, Glycolic Acid diffuses very efficiently through the stratum corneum, promoting homogeneous exfoliation that helps improve the superficial quality of the skin, optimise its texture and restore a more even, radiant and revitalised appearance.
More than a standalone peel, Glycolic Peel 50% forms part of the TherapDerma Clinical Ecosystem™, a working model based on progressive protocols integrating chemical peels, mesotherapy, medical-aesthetic technologies and home care to achieve reproducible, safe and cumulative results.

What makes Glycolic Peel 50% different?

The objective of a professional peel is not simply to exfoliate the skin.
Its true value lies in selecting the appropriate concentration for each clinical situation and using it within a personalised therapeutic strategy.
Glycolic Peel 50% has been developed to provide more intensive epidermal renewal than lower concentrations, enabling treatment of skin requiring greater exfoliating capacity while maintaining the principles of control, safety and clinical progression.
Its formulation allows progressive protocols tailored to each patient’s biological response, always respecting skin physiology and promoting gradual treatment progression.
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What is Glycolic Acid?
Glycolic Acid is one of the most widely used Alpha Hydroxy Acids in aesthetic medicine due to its high capacity to promote the physiological renewal of the epidermis.
It is traditionally derived from sugar cane and has the lowest molecular weight among the AHAs, a characteristic that enables uniform penetration through the superficial layers of the skin and explains its widespread use in professional chemical exfoliation protocols.
Its cosmetic mechanism promotes the progressive removal of accumulated corneocytes, encouraging a more even skin surface and a visible improvement in the overall appearance of the skin.
For this reason, Glycolic Acid is one of the benchmark active ingredients in professional programmes aimed at skin rejuvenation, improving skin texture and optimising the superficial quality of the epidermis.
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When should Glycolic Peel 50% be selected?
Glycolic Peel 50% is particularly indicated when professional diagnosis determines the need for more active epidermal renewal than that achieved with introductory concentrations and when the patient demonstrates adequate skin tolerance.
It may be incorporated into protocols for patients presenting with:
• Moderate photoageing;
• Irregular skin texture;
• Thickened or devitalised skin;
• Visibly enlarged pores;
• More pronounced fine lines;
• Superficial irregularities resulting from sun damage;
• Superficial post-acne marks;
• Noticeable loss of radiance;
• Progressive professional skin rejuvenation programmes;
• Skin preparation for advanced combination aesthetic medicine protocols.
Patient selection and individual clinical assessment remain essential elements in determining the indication for treatment.
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Position within the TherapDerma Clinical Ladder™
At TherapDerma, we understand that the concentration of a chemical peel is not a measure of superiority, but rather a tool for adapting treatment to each patient’s real needs.
Within the TherapDerma Clinical Ladder™, each concentration occupies a specific position:
Glycolic Peel 20% initiates epidermal renewal and skin preparation protocols.
Glycolic Peel 35% intensifies superficial exfoliation and promotes a more noticeable improvement in texture and radiance.
Glycolic Peel 50% represents the next evolutionary level for professionals who require greater epidermal renewal capacity within personalised and properly planned protocols.
This stepwise approach makes it possible to develop treatments that are more predictable, safer and adapted to each patient’s clinical progression.
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TherapDerma Philosophy
At TherapDerma, we believe that the best results are not achieved through aggressive procedures, but through intelligent protocols that respect the biology of the skin.
Every chemical peel forms part of a broader therapeutic strategy in which diagnosis, patient selection, treatment progression and combination with other medical-aesthetic solutions play a fundamental role.
For this reason, Glycolic Peel 50% has been designed to integrate naturally into the TherapDerma Clinical Ecosystem™, enabling the development of personalised protocols combining chemical peels, mesotherapy, regenerative technologies and home care skincare under a single scientific approach.
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TherapDerma Conclusion
Glycolic Peel 50% represents an advanced tool for professionals wishing to intensify epidermal renewal in a controlled, safe and predictable manner.
Its formulation makes it possible to implement more demanding rejuvenation protocols, optimising the superficial quality of the skin through progressive exfoliation integrated within the TherapDerma Clinical Ecosystem™, where every treatment forms part of a personalised clinical plan designed to achieve natural, cumulative and sustainable results.

Clinical Benefits

Intensive exfoliation to visibly improve skin quality
TherapDerma Glycolic Peel 50% has been developed for professionals seeking more intensive epidermal renewal within personalised aesthetic medicine protocols.
Its high concentration enhances the controlled removal of accumulated corneocytes, promoting a more even skin surface and the progressive improvement of various parameters related to the skin’s visual quality.
When correctly incorporated into a professional protocol, its benefits develop cumulatively from session to session, always respecting the physiological timing of epidermal renewal.
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✨ Intensive Epidermal Renewal
What are the clinical benefits?
Controlled exfoliation promotes a more dynamic cellular turnover, helping to accelerate the natural renewal of the superficial layers of the epidermis.
Clinical Benefits
✔ Promotes the removal of keratinised cells.
✔ Stimulates more active epidermal renewal.
✔ Progressively improves the overall appearance of the skin.
✔ Contributes to a more even skin surface.
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🌟 Advanced Texture Refinement
What are the clinical benefits?
The progressive renewal of the skin surface helps smooth visible irregularities, improving skin relief and providing a more even texture.
Clinical Benefits
✔ More refined texture.
✔ Smoother surface.
✔ Reduced sensation of roughness.
✔ Improved overall aesthetic quality.
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💎 Enhanced Skin Radiance
What are the clinical benefits?
A renewed epidermis reflects light more evenly, promoting skin with a fresher, healthier and more revitalised appearance.
Clinical Benefits
✔ Radiant appearance.
✔ Natural glow effect.
✔ Visibly revitalised skin.
✔ Greater sensation of freshness.
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🎯 Visible Improvement in Skin Uniformity
What are the clinical benefits?
The homogeneous renewal of the superficial layers promotes a more even skin appearance, helping to visually minimise minor superficial irregularities.
Clinical Benefits
✔ More even appearance.
✔ Improved visual uniformity.
✔ More balanced skin.
✔ More refined finish.
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🔬 Refinement of Pore Appearance
What are the clinical benefits?
The progressive improvement in superficial texture helps visibly reduce the apparent size of pores, providing skin with a more even appearance.
Clinical Benefits
✔ Less noticeable pores.
✔ More regular skin relief.
✔ Improved surface definition.
✔ Cleaner appearance.
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🌿 Visible Reduction of Fine Lines
What are the clinical benefits?
Intensive epidermal renewal promotes a smoother-looking skin surface, helping to visibly soften the first expression lines and other early signs of ageing.
Clinical Benefits
✔ Rejuvenated appearance.
✔ Visibly smoother skin.
✔ Improved continuity of skin relief.
✔ More rested appearance.
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⚡ Optimisation of Skin Receptivity
What are the clinical benefits?
A properly renewed epidermis presents a more even surface for integration into advanced cosmetic protocols, facilitating the sequential planning of professional treatments.
Clinical Benefits
✔ Excellent skin preparation.
✔ Greater therapeutic versatility.
✔ Integration into personalised protocols.
✔ Progressive and structured approach.
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📈 Cumulative Results
The benefits of Glycolic Peel 50% do not depend exclusively on a single session.
Epidermal renewal is a progressive biological process; therefore, the most visible changes appear as the protocol progresses and the recommended intervals between sessions are respected.
The combination of appropriate patient selection, individualised planning and professional follow-up makes it possible to achieve more consistent and sustainable medium- and long-term results.
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CLINICAL SUMMARY
Main Benefits of Glycolic Peel 50%
✔ Intensive epidermal renewal.
✔ Advanced texture refinement.
✔ Enhanced skin radiance.
✔ Improved visual skin uniformity.
✔ Refinement of pore appearance.
✔ Reduction of fine lines.
✔ Optimisation of skin receptivity.
✔ Progressive and cumulative results.
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THERAPDERMA CLINICAL CONCLUSION
The true value of Glycolic Peel 50% lies in its ability to provide more intensive epidermal renewal while maintaining a high level of professional control.
Integrated into personalised protocols, it progressively improves the superficial quality of the skin and expands the professional’s therapeutic possibilities through an approach based on clinical planning, safety and the gradual evolution of results.

Why Choose Glycolic Peel 50%?

The right concentration for more demanding epidermal renewal protocols
In professional aesthetic medicine, the success of a treatment does not depend on using the peel with the highest concentration, but on selecting the formulation that best matches the clinical diagnosis, the condition of the skin and each patient’s therapeutic objectives.
Glycolic Peel 50% has been developed for professionals who need to increase the intensity of chemical exfoliation within well-structured protocols while maintaining a high level of control throughout the entire procedure.
Its formulation makes it possible to expand therapeutic options when lower concentrations no longer provide the desired degree of epidermal renewal.
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WHEN IS IT THE BEST OPTION?
Glycolic Peel 50% is particularly suitable when the professional wishes to perform a more intensive epidermal renewal in appropriately selected patients.
It may be considered an excellent option in situations such as:
✔ advanced skin rejuvenation programmes;
✔ moderate photoageing;
✔ thickened skin or skin with irregular texture;
✔ significant loss of radiance;
✔ visibly enlarged pores;
✔ superficial post-acne marks;
✔ more evident fine lines;
✔ patients accustomed to lower-concentration chemical peels.
The indication should always be established following an individual clinical assessment.
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WHO HAS IT BEEN DESIGNED FOR?
Glycolic Peel 50% is intended for professionals who wish to incorporate higher-intensity chemical exfoliation protocols into clinical practice based on diagnosis and treatment personalisation.
Its use requires experience in assessing skin type, cutaneous response and the sequential planning of treatment sessions to ensure a safe and predictable procedure.
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THERAPDERMA CLINICAL LADDER™
Each concentration corresponds to a different stage within the progression of treatment.
Glycolic Peel 20%
Ideal for:
✔ first contact with chemical peels;
✔ skin preparation;
✔ superficial maintenance;
✔ skin with low tolerance.
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Glycolic Peel 35%
Ideal for:
✔ progressive renewal programmes;
✔ visible improvement in skin texture;
✔ moderate loss of radiance;
✔ initial rejuvenation protocols.
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Glycolic Peel 50%
Ideal for:
✔ intensive epidermal renewal protocols;
✔ appropriately selected patients;
✔ skin requiring greater superficial refinement;
✔ more advanced anti-ageing programmes;
✔ integration into combination aesthetic medicine treatments;
✔ professionals experienced in chemical peels

QUICK SELECTION GUIDE
Clinical Objective Recommended Peel
First professional peel ✅ Glycolic Peel 20%
Skin preparation ✅ Glycolic Peel 20%
Progressive superficial renewal ✅ Glycolic Peel 35%
Visible improvement in skin texture ✅ Glycolic Peel 35%
Initial photoageing ✅ Glycolic Peel 35%
Intensive epidermal renewal ✅ Glycolic Peel 50%
Moderate photoageing ✅ Glycolic Peel 50%
Marked irregular skin texture ✅ Glycolic Peel 50%
Sensitive skin ✅ Mandelic Peel
Dry or dehydrated skin ✅ Lactic Peel
This guidance facilitates the consistent selection of the appropriate peel within a professional protocol, respecting the clinical progression of each patient and avoiding unnecessarily aggressive treatments.
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WHY INTEGRATE IT INTO A PROGRESSIVE PROGRAMME?
The best results are not usually achieved by increasing treatment intensity in isolation, but by building a stepwise protocol that allows the skin to adapt progressively to each stage of treatment.
Within this context, Glycolic Peel 50% represents an evolutionary step in epidermal renewal programmes, enabling the professional to progress towards more intensive treatments when the patient’s clinical response and tolerance justify it.
This strategy promotes more precise treatment planning, optimises therapeutic continuity and allows treatment to be personalised according to the evolution observed at each session.
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THERAPDERMA CLINICAL CONCLUSION
Glycolic Peel 50% is a highly valuable tool for professionals seeking to expand their therapeutic options through more intensive epidermal renewal protocols.
Its role within the TherapDerma Clinical Ladder™ makes it possible to structure progressive treatments tailored to the individual characteristics of each patient, reinforcing an approach based on the appropriate selection of concentration, clinical planning and the achievement of visible, natural and sustainable results.

Areas of Application

One peel. Multiple clinical possibilities.
TherapDerma Glycolic Peel 50% has been developed to be integrated into different professional epidermal renewal protocols, making it possible to treat various anatomical areas according to the characteristics of the skin, the clinical diagnosis and the established therapeutic objectives.
Although the facial region is the most frequent indication, its application may be extended to other areas showing signs of photoageing, irregular skin texture or loss of skin quality, always following professional assessment.
Each area has different anatomical characteristics; therefore, the intensity of the treatment should always be adapted individually.
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FACE
The main clinical indication
The face represents the area where Glycolic Peel 50% offers its greatest therapeutic potential.
Continuous exposure to sunlight, pollution, physiological ageing and slower cellular renewal make this region the primary candidate for intensive chemical exfoliation protocols.
It may be incorporated into treatments designed to progressively improve:
✔ skin texture;
✔ radiance;
✔ skin tone uniformity;
✔ the appearance of pores;
✔ superficial fine lines;
✔ overall skin quality.
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NECK
Aesthetic continuity of facial rejuvenation
The skin of the neck has a lower dermal density and a different biological behaviour from that of the face.
For this reason, treatment planning should be carefully adapted to its characteristics.
When justified by the clinical diagnosis, Glycolic Peel 50% may form part of protocols designed to improve the superficial quality of this region and maintain a harmonious aesthetic transition between the face and the neck.
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DÉCOLLETAGE
One of the most photo-exposed areas
The décolletage is often one of the first areas to show the cumulative effects of ultraviolet radiation.
The controlled epidermal renewal promoted by Glycolic Peel 50% may be integrated into programmes designed to progressively improve the superficial texture, radiance and visual uniformity of this area.
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BACK OF THE HANDS
Rejuvenation of a frequently overlooked area
The hands quickly reflect skin ageing due to continuous sun exposure and environmental factors.
Glycolic Peel 50% may be incorporated into professional protocols designed to improve the overall appearance of the back of the hands, promoting skin with a more even and refined appearance.
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BACK
Specific protocols for selected patients
In appropriately assessed patients, the peel may be used on localised areas of the back when the clinical objective is to promote epidermal renewal and improve the superficial quality of the skin.
The size of the treatment area and the protocol should always be adapted to the patient’s individual characteristics.
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SHOULDERS AND ARMS
Photo-exposed areas of aesthetic interest
The shoulders and the outer aspect of the arms may also benefit from epidermal renewal protocols when they present superficial irregularities or signs of photoageing.
Treatment planning should respect the thickness and sensitivity of each patient’s skin in order to maintain a safe and controlled procedure.
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CLINICAL PRIORITISATION OF TREATMENT AREAS
Anatomical Area Clinical Potential
⭐⭐⭐⭐⭐ Face
⭐⭐⭐⭐ Neck
⭐⭐⭐⭐ Décolletage
⭐⭐⭐⭐ Back of the Hands
⭐⭐⭐ Back (selected areas)
⭐⭐⭐ Shoulders and Arms
This classification serves as a guideline to facilitate clinical planning and the selection of the areas with the greatest therapeutic potential.
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MULTI-AREA PROTOCOLS
In many patients, the best results are not achieved by treating a single anatomical region, but by developing protocols that maintain harmony between different photo-exposed areas.
The most common combinations include:
✔ Face + neck.
✔ Face + neck + décolletage.
✔ Face + back of the hands.
✔ Complete facial programmes combined with localised body treatments.
The choice will always depend on the professional diagnosis and the established aesthetic objectives.
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CLINICAL CONSIDERATIONS
Before selecting the treatment area, the professional should assess:
✔ anatomical characteristics;
✔ skin thickness;
✔ skin sensitivity;
✔ degree of photoageing;
✔ aesthetic history;
✔ therapeutic objectives;
✔ the patient’s recovery capacity.
Each protocol should be adapted to the individual needs of the patient and evolve according to the observed clinical response.
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QUICK SUMMARY
Glycolic Peel 50% may be incorporated into protocols for:
✔ Face.
✔ Neck.
✔ Décolletage.
✔ Back of the Hands.
✔ Back (selected areas).
✔ Shoulders and Arms.
✔ Other areas, always according to professional judgement.
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THERAPDERMA CONCLUSION
The versatility of Glycolic Peel 50% makes it possible to integrate intensive epidermal renewal into different anatomical regions through personalised and carefully planned protocols.
The correct selection of the treatment area, together with an accurate diagnosis and an individualised adaptation of the protocol, makes it possible to develop safer, more consistent procedures aimed at progressively improving skin quality within the TherapDerma Clinical Ecosystem™.

How Does It Work?

Understanding the biological process helps optimise clinical results
Although the application of TherapDerma Glycolic Peel 50% lasts only a few minutes, the biological response it triggers continues to evolve over several days.
Each session represents the beginning of a carefully controlled physiological process whose objective is to promote the progressive renewal of the epidermis and improve the superficial quality of the skin.
Understanding each of these stages enables the professional to plan more precise protocols, correctly interpret the clinical evolution and establish realistic expectations for each patient.
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EVERYTHING BEGINS ON THE SURFACE OF THE SKIN
The peel first comes into contact with the stratum corneum, the outermost layer of the epidermis.
Over time, this layer accumulates aged corneocytes, keratin residues and irregularities that reduce skin radiance and alter skin texture.
The application of Glycolic Peel 50% initiates a controlled chemical exfoliation that promotes the progressive removal of these superficial cells.
This process represents the first step towards more active epidermal renewal.
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STEP 1
Controlled Chemical Exfoliation
Glycolic Acid begins by acting on the surface of the skin, progressively reducing the cohesion between corneocytes.
As a result, the epidermis initiates a physiological process of controlled desquamation that facilitates the removal of the most superficial layers of the skin.
This action develops uniformly when the protocol has been correctly planned.
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STEP 2
Activation of Epidermal Renewal
Once exfoliation has begun, the epidermis responds by accelerating its natural renewal process.
New cells begin to rise from the deeper layers towards the surface, progressively replacing the aged cells removed during treatment.
The speed of this process will depend on the biological characteristics of each individual patient.
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STEP 3
Progressive Reorganisation of the Skin Surface
As epidermal renewal progresses, the skin develops a more homogeneous structure.
The surface gradually becomes more regular, improving skin texture and promoting a more even appearance.
This change does not occur immediately, but develops gradually from one treatment session to the next.
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STEP 4
Visible Improvement in Skin Quality
The reorganisation of the epidermis promotes better light reflection on the skin surface.
As a result, the skin may progressively present:
✔ greater radiance;
✔ more refined texture;
✔ a more even appearance;
✔ visually less noticeable pores;
✔ a fresher and more revitalised appearance.
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STEP 5
Cumulative Results
Each session acts as a new biological stimulus.
When the protocol respects the physiological recovery times, the benefits obtained accumulate progressively, allowing more predictable treatments with a more consistent clinical evolution.
For this reason, Glycolic Peel 50% achieves its maximum performance when it forms part of a structured and personalised programme.
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WHY IS pH SO IMPORTANT?
The intensity of a chemical peel does not depend exclusively on its concentration.
The behaviour of Glycolic Acid is also influenced by factors such as the pH of the formulation and the balance between free acid and partially neutralised acid.
This combination makes it possible to achieve intensive exfoliation while maintaining a high level of professional control throughout the procedure.
These concepts are explained in greater depth in the Scientific Foundations section.
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A DIFFERENT RESPONSE IN EVERY PATIENT
The clinical evolution is never exactly the same in two individuals.
Factors such as:
✔ biological age;
✔ thickness of the stratum corneum;
✔ phototype;
✔ degree of photoageing;
✔ skincare routine;
✔ previous treatments;
✔ individual regenerative capacity;
directly influence the response observed after each treatment session.
For this reason, every protocol should be individually adapted.
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SEQUENCE OF THE BIOLOGICAL PROCESS
Professional application

Controlled chemical exfoliation

Progressive removal of corneocytes

Physiological renewal of the epidermis

Reorganisation of the skin surface

Progressive improvement in skin texture

Increase in radiance

Overall optimisation of skin quality
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KEY MECHANISMS
Glycolic Peel 50% promotes:
✔ Controlled chemical exfoliation.
✔ Intensive epidermal renewal.
✔ Progressive reorganisation of the skin surface.
✔ Improvement in skin texture.
✔ Increased radiance.
✔ Optimisation of the visual quality of the skin.
✔ Cumulative results through personalised protocols.
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THERAPDERMA CONCLUSION
Understanding how Glycolic Peel 50% works enables the professional to go beyond the simple application of the product.
Each session triggers an organised biological sequence that continues to evolve during the days following treatment and, when integrated into a personalised protocol, promotes more intensive epidermal renewal, a progressive improvement in skin quality and consistent, natural and sustainable clinical results within the TherapDerma Clinical Ecosystem™.

Mechanism of Action

The science behind epidermal renewal
TherapDerma Glycolic Peel 50% exerts its action through a carefully controlled chemical exfoliation mechanism that acts primarily on the epidermis, promoting the progressive reorganisation of its surface and improving the visual quality of the skin.
Its biological behaviour is based on the interaction between Glycolic Acid and the structures responsible for maintaining the cohesion of the stratum corneum, initiating a physiological renewal process that continues to evolve during the days following treatment.
Understanding this mechanism allows the professional to correctly interpret the clinical evolution and select more precise protocols for each patient.
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ACTION ON THE STRATUM CORNEUM
The stratum corneum constitutes the skin’s first protective barrier.
It is composed of mature corneocytes arranged in multiple layers and joined together by specialised protein complexes known as corneodesmosomes.
These structures maintain the cohesion of the epidermis and regulate the physiological desquamation process.
With ageing and environmental exposure, this process may slow down, promoting the accumulation of aged corneocytes and creating a more irregular skin surface.
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MODULATION OF CORNEODESMOSOMES
The main cosmetic mechanism of Glycolic Acid consists of promoting the progressive reduction of cohesion between superficial corneocytes.
This action facilitates a more uniform and controlled desquamation while respecting the biological rhythm of epidermal renewal.
As a result, the skin surface progressively eliminates aged cells and allows the emergence of newer epidermal layers.
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ACCELERATION OF EPIDERMAL CELL TURNOVER
Controlled exfoliation triggers a physiological response that promotes the natural turnover of the epidermis.
New cells generated in the basal layers gradually migrate towards the surface, replacing the cells removed during treatment.
This process contributes to improving the organisation of the epidermal tissue and promotes skin with a more even appearance.
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REORGANISATION OF THE SKIN SURFACE
As epidermal renewal progresses, the superficial architecture of the skin becomes more regular.
The reorganisation of the stratum corneum promotes:
✔ a more homogeneous texture;
✔ improved light reflection;
✔ a smoother surface;
✔ a more even appearance;
✔ improved visual skin quality.
These changes appear progressively as the treatment protocol evolves.
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EFFECT ON THE SKIN MICRORELIEF
The skin microrelief corresponds to the set of small irregularities present on the epidermal surface.
The controlled renewal promoted by Glycolic Peel 50% contributes to reorganising this superficial relief, providing skin with a visibly more refined and uniform appearance.
As a result, the skin reflects light more evenly, increasing the sensation of radiance and freshness.
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BIOLOGICAL PREPARATION FOR SUBSEQUENT TREATMENTS
A renewed epidermis presents a more uniform and organised surface.
For this reason, Glycolic Peel 50% may form part of sequential protocols in which epidermal renewal constitutes the first phase before incorporating other personalised therapies, always according to the professional’s clinical judgement.
This strategy makes it possible to integrate the peel into broader aesthetic medicine programmes without altering the skin’s natural physiology.
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SEQUENCE OF THE MECHANISM OF ACTION
Professional application

Action on the stratum corneum

Progressive reduction of cohesion between corneocytes

Controlled chemical exfoliation

Stimulation of epidermal cell turnover

Reorganisation of the skin microrelief

Improvement in skin texture and radiance

Progressive optimisation of the superficial quality of the skin
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SCIENCE AT A GLANCE™
Parameter Glycolic Peel 50%
Active ingredient Glycolic Acid
Family Alpha Hydroxy Acids (AHA)
Concentration 50%
Primary level of action Epidermis
Target structure Stratum corneum
Biological action Modulation of cohesion between corneocytes
Physiological outcome Progressive epidermal renewal
Cosmetic objective Improvement of the superficial quality of the skin
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BIOLOGICAL FOUNDATION
The mechanism of action of Glycolic Peel 50% is based on promoting the physiological renewal of the epidermis through controlled chemical exfoliation.
The progressive reorganisation of the stratum corneum makes it possible to optimise the skin microrelief and improve the overall appearance of the skin without altering its natural regeneration mechanisms.
This balance between efficacy, control and respect for skin physiology constitutes one of the fundamental principles of modern aesthetic medicine.
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THERAPDERMA CONCLUSION
The true value of Glycolic Peel 50% lies in understanding that its action is not limited to removing superficial cells.
Its biological mechanism promotes organised epidermal renewal that progressively improves the architecture of the skin surface, making it possible to develop more predictable, personalised and scientifically based protocols within the TherapDerma Clinical Ecosystem™.

Scientific Foundations

The formulation determines the behaviour of the peel
In aesthetic medicine, the effectiveness of a chemical peel does not depend exclusively on the concentration of the acid.
The clinical behaviour of the formulation results from the balance between different physicochemical parameters that determine the speed of action, the availability of free acid and the intensity of exfoliation.
Understanding these principles enables the professional to interpret the skin response more accurately and select protocols tailored to the specific needs of each patient.
In TherapDerma Glycolic Peel 50%, all these factors have been carefully considered to provide intensive, progressive and controlled exfoliation within exclusively professional protocols.
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CONCENTRATION
Much more than a percentage
Concentration indicates the amount of Glycolic Acid present in the formulation.
In Glycolic Peel 50%, this percentage provides a greater capacity for epidermal renewal than the lower concentrations within the same range.
However, a higher concentration does not automatically mean a more aggressive treatment or better results.
Its behaviour will always depend on its interaction with other scientific factors that regulate the actual activity of the peel.
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THE ROLE OF pH
The pH represents the degree of acidity of the formulation and is one of the most important parameters in the design of a chemical peel.
At the same concentration, small variations in pH can significantly modify the amount of acid available to act on the skin.
For this reason, two peels containing the same percentage of Glycolic Acid may produce different clinical responses when their pH values differ.
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THE MEANING OF pKa
The pKa is a physicochemical constant specific to Glycolic Acid.
Its value (3.86) makes it possible to understand the balance between the ionised fraction and the non-ionised fraction of the acid.
When the pH of the formulation approaches the pKa, the proportion of free acid available to act on the epidermis changes.
This concept explains why the behaviour of a peel cannot be interpreted solely on the basis of its concentration.
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FREE ACID
The true protagonist of exfoliation
Not all the Glycolic Acid present in the formulation acts simultaneously on the skin.
The fraction known as free acid is the one that participates most directly in the chemical exfoliation process.
The availability of this fraction depends on the balance between:
✔ concentration;
✔ pH;
✔ pKa.
This balance makes it possible to achieve intensive action while maintaining a high level of professional control.
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MOLECULAR WEIGHT
Glycolic Acid has the lowest molecular weight of all Alpha Hydroxy Acids (AHAs).
This characteristic promotes a uniform distribution across the skin surface and explains why it remains one of the most widely used active ingredients in professional epidermal renewal protocols.
Its molecular size is one of the reasons for its extensive application in aesthetic medicine.
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DEPTH OF THE PEEL
The depth reached during a chemical peel never depends exclusively on the formulation.
It is also influenced by factors such as:
✔ skin preparation;
✔ exposure time;
✔ number of layers applied;
✔ application technique;
✔ individual biological response;
✔ neutralisation.
For this reason, the same product may produce different clinical responses depending on the protocol used.
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THE IMPORTANCE OF NEUTRALISATION
In peels formulated with Glycolic Acid, neutralisation is an essential stage of the procedure.
Its function is to stop the activity of the acid once the intended therapeutic objective has been achieved.
This step makes it possible to maintain a high level of control during treatment and forms part of good clinical practice in the use of professional chemical peels.
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KEY SCIENTIFIC PARAMETERS
Parameter Glycolic Peel 50%
Active ingredient Glycolic Acid
Chemical family Alpha Hydroxy Acids (AHA)
Concentration 50%
pH Approximately 3.5
pKa 3.86
Molecular weight The lowest among AHAs
Neutralisation Mandatory
Use Professional use only
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WHY IS IT IMPORTANT TO UNDERSTAND THESE CONCEPTS?
When the professional correctly understands the relationship between concentration, pH, pKa, free acid and application technique, they can:
✔ select the most appropriate peel;
✔ adapt the protocol to each patient;
✔ improve clinical predictability;
✔ optimise treatment safety;
✔ achieve more consistent and reproducible results.
Science enables better clinical decision-making.
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THERAPDERMA CONCLUSION
Glycolic Peel 50% has been developed based on physicochemical principles widely recognised in dermatology and aesthetic medicine.
The interaction between concentration, pH, pKa, free acid and professional technique determines the actual behaviour of the peel and makes it possible to develop intensive epidermal renewal protocols based on precision, control and safety.
At TherapDerma, we understand that clinical excellence begins with scientific knowledge and with the professional’s ability to transform that knowledge into personalised treatments and consistent results.

Indications

When should Glycolic Peel 50% be selected?
The selection of a chemical peel should always be made following a comprehensive clinical assessment, taking into account the skin type, treatment objectives, patient history and the expected response to the protocol.
TherapDerma Glycolic Peel 50% is particularly indicated when the professional wishes to perform a more intensive epidermal renewal in appropriately selected patients while maintaining a controlled and progressive procedure.
The choice of this concentration should form part of an individualised therapeutic strategy and should never be based solely on the percentage of the acid.
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PHOTOAGEING
Chronic exposure to ultraviolet radiation accelerates the skin ageing process and promotes progressive alterations to the epidermal surface.
Glycolic Peel 50% may be incorporated into protocols designed to improve the appearance of photoaged skin by promoting more active superficial renewal and a more even skin appearance.
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IRREGULAR SKIN TEXTURE
Irregularities in the skin surface are among the most common reasons for consultation in aesthetic medicine.
The epidermal renewal promoted by Glycolic Peel 50% encourages a more homogeneous skin surface and improved visual skin quality, making it an option of interest for protocols aimed at improving skin texture.
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LOSS OF RADIANCE
Over time, the accumulation of corneocytes and the reduction in epidermal turnover may cause the skin to appear dull.
Controlled chemical exfoliation promotes better light reflection on the skin surface, providing the skin with a brighter and more revitalised appearance.
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SUPERFICIAL FINE LINES
The first manifestations of skin ageing are often expressed through small irregularities in the skin surface.
When they form part of the clinical diagnosis, Glycolic Peel 50% may be integrated into epidermal renewal programmes aimed at visibly improving the smoothness and uniformity of the skin.
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VISIBLE PORES
The accumulation of keratin and irregularities in the skin surface may make pores appear more noticeable.
The progressive improvement in texture promoted by Glycolic Peel 50% contributes to visibly reducing their appearance, providing a more even skin surface.
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SUPERFICIAL POST-ACNE MARKS
In appropriately selected patients, Glycolic Peel 50% may be incorporated into professional protocols designed to improve the appearance of superficial post-acne marks, provided that the skin presents no active inflammatory lesions and that the treatment is considered appropriate following clinical assessment.
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THICKENED OR DULL SKIN
Skin with a thicker stratum corneum often benefits from protocols aimed at promoting more intensive epidermal renewal.
Glycolic Peel 50% may form part of programmes designed to improve the appearance of this type of skin, helping to restore a smoother and more even surface.
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PREPARATION FOR COMBINATION PROTOCOLS
The controlled renewal of the epidermis makes Glycolic Peel 50% a valuable tool within sequential aesthetic medicine programmes.
It may be used as the initial phase of personalised protocols that subsequently integrate other professional solutions, always according to the diagnosis and the established therapeutic plan.
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MAINTENANCE OF SKIN QUALITY
In patients who have already completed skin rejuvenation or epidermal renewal programmes, Glycolic Peel 50% may be incorporated into maintenance strategies aimed at preserving the superficial quality of the skin and supporting the continuity of the results achieved.
The frequency of these sessions should always be established on an individual basis.
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SUMMARY OF THE MAIN INDICATIONS
Glycolic Peel 50% may be integrated into professional protocols for:
✔ Photoageing.
✔ Irregular skin texture.
✔ Loss of radiance.
✔ Superficial fine lines.
✔ Visible pores.
✔ Superficial post-acne marks.
✔ Thickened or devitalised skin.
✔ Preparation for combination treatments.
✔ Skin quality maintenance programmes.
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THERAPDERMA CLINICAL CONCLUSION
Glycolic Peel 50% is a versatile tool for professionals wishing to incorporate more intensive epidermal renewal into personalised protocols.
The correct selection of indications, together with an accurate diagnosis and individualised planning, makes it possible to develop treatments that are consistent with the specific needs of each patient, reinforcing the scientific and progressive approach that characterises the TherapDerma Clinical Ecosystem™.

Contraindications

Safety begins with a proper clinical assessment
Every professional chemical peel should only be performed after an individual patient assessment.
Identifying potential contraindications is an essential part of the diagnostic process and makes it possible to select the most appropriate treatment, reduce the risk of complications and ensure responsible clinical practice.
With TherapDerma Glycolic Peel 50%, patient safety depends as much on the correct selection of the protocol as on respecting the situations in which treatment is not indicated.
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PREGNANCY AND BREASTFEEDING
As a precautionary measure, chemical peels are not recommended during pregnancy or breastfeeding.
Although the systemic absorption of topically applied Glycolic Acid is limited, routine clinical practice recommends postponing these procedures until after these periods have ended.
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ACTIVE SKIN INFECTIONS
Treatment should not be performed on skin presenting active infectious processes.
These include:
✔ active herpes simplex;
✔ bacterial infections;
✔ fungal infections;
✔ viral lesions;
✔ acute inflammatory processes.
The peel may be considered once the condition has completely resolved.
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WOUNDS OR IMPAIRED SKIN INTEGRITY
Glycolic Peel 50% should not be applied to areas presenting:
✔ open wounds;
✔ abrasions;
✔ recent burns;
✔ skin erosions;
✔ recent surgical procedures that have not completely healed.
The skin must be fully intact before treatment is initiated.
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ACTIVE DERMATOSES
The presence of active inflammatory skin diseases requires particularly careful assessment.
These include:
✔ eczema;
✔ active dermatitis;
✔ psoriasis in the active phase;
✔ other inflammatory dermatoses localised within the treatment area.
In these cases, the procedure should be postponed until the condition has stabilised.
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HYPERSENSITIVITY TO THE PRODUCT
The treatment is contraindicated in patients with a known history of hypersensitivity to Glycolic Acid or to any component of the formulation.
Where increased sensitivity is suspected, the professional should consider more appropriate therapeutic alternatives.
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RECENT DERMATOLOGICAL TREATMENTS
Before performing the peel, it is important to review treatments received during the previous weeks.
Particular attention should be paid to patients who have recently undergone:
✔ oral retinoid therapy;
✔ ablative procedures;
✔ aggressive laser treatments;
✔ other high-intensity chemical peels;
✔ treatments that may impair the skin barrier function.
The decision should always be individualised according to the clinical evolution.
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INTENSE SUN EXPOSURE
It is not recommended to begin a Glycolic Peel 50% protocol when the patient has had recent and intense sun exposure or when adequate photoprotection cannot be guaranteed during the recovery period.
Protection against ultraviolet radiation is an essential part of the treatment.
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OTHER SITUATIONS REQUIRING ASSESSMENT
The professional should carefully assess treatment in patients with:
✔ a history of post-inflammatory hyperpigmentation;
✔ extremely reactive skin;
✔ impaired wound healing;
✔ systemic diseases that may interfere with skin recovery;
✔ medical treatments that may modify the skin response.
Each case should be evaluated individually.
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SAFETY CHECKLIST
Before applying Glycolic Peel 50%, it is recommended to confirm that:
☐ The skin is intact.
☐ There are no active infections.
☐ The patient is not pregnant or breastfeeding.
☐ There is no history of hypersensitivity to the product.
☐ Recent dermatological treatments have been reviewed.
☐ The patient understands the post-treatment care instructions.
☐ The patient is able to comply with appropriate photoprotection measures.
A systematic assessment helps minimise risks and improves the safety of the procedure.
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CLINICAL SUMMARY
Do not use Glycolic Peel 50% in the following cases:
✔ Pregnancy or breastfeeding.
✔ Active herpes.
✔ Skin infections.
✔ Open wounds or recent burns.
✔ Active dermatitis, eczema or psoriasis.
✔ Known hypersensitivity to the product.
✔ Recent dermatological treatments that contraindicate the procedure.
✔ Intense sun exposure without the possibility of adequate photoprotection.
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THERAPDERMA CONCLUSION
The effectiveness of a chemical peel begins with the correct indication and appropriate patient selection.
At TherapDerma, safety is a fundamental principle of all professional protocols. Identifying contraindications, respecting skin physiology and individualising treatment make it possible to develop safer, more predictable procedures aimed at achieving high-quality results within responsible clinical practice.

Professional Application

A procedure based on diagnosis, precision and clinical control
The success of a professional chemical peel does not depend solely on the formulation used.
Correct patient assessment, proper skin preparation, the application technique and subsequent follow-up are essential factors in achieving safe, reproducible results tailored to each clinical situation.
TherapDerma Glycolic Peel 50% has been developed exclusively for professional use and should always be incorporated into carefully planned protocols, respecting both skin physiology and the biological evolution of each patient.
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PRE-TREATMENT CLINICAL ASSESSMENT
Before starting any treatment, the professional should perform a comprehensive clinical assessment to confirm the patient’s suitability for this procedure.
The initial assessment should include:
✔ skin type;
✔ phototype;
✔ degree of photoageing;
✔ thickness of the stratum corneum;
✔ skin sensitivity;
✔ dermatological history;
✔ recent aesthetic treatments;
✔ patient expectations.
This assessment represents the first step in developing a safe and personalised protocol.
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SKIN PREPARATION
Proper preparation promotes uniform peel application and improves procedural control.
Before starting, it is recommended to:
✔ thoroughly cleanse the treatment area;
✔ remove all traces of make-up, sunscreen and sebum;
✔ degrease the skin surface when indicated;
✔ protect the most sensitive areas, such as the corners of the mouth, the nasal folds and the periocular area.
The skin must be completely clean and dry before applying the product.
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DURING APPLICATION
The peel should be applied using a uniform and systematic technique.
Throughout the procedure, the professional should continuously observe the skin response and adapt the treatment according to the clinical evolution.
It is important to monitor:
✔ uniformity of application;
✔ skin response;
✔ patient comfort;
✔ exposure time;
✔ the need for neutralisation.
The treatment should always be individualised.
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THE IMPORTANCE OF CLINICAL OBSERVATION
Every skin responds differently.
For this reason, the evolution observed during the treatment session has greater clinical value than any rigid protocol.
The professional’s experience allows the skin response to be correctly interpreted and the appropriate moment to end the procedure to be determined.
Safety should always take precedence over treatment intensity.
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PEEL NEUTRALISATION
For peels formulated with Glycolic Acid, neutralisation is an essential stage of the procedure.
Its purpose is to stop the action of the acid once the desired clinical effect has been achieved.
After neutralisation, the skin should be carefully cleansed before continuing with the post-treatment protocol.
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IMMEDIATE AFTERCARE
Once the session has been completed, it is recommended to apply products designed to promote skin comfort and support the recovery of the skin barrier function.
The professional should advise the patient to:
✔ maintain adequate hydration;
✔ use a broad-spectrum sunscreen every day;
✔ avoid direct sun exposure;
✔ avoid potentially irritating products during the first few days;
✔ strictly follow the recommended home care programme.
Post-treatment care forms part of the treatment itself and contributes to optimising the clinical outcome.
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PATIENT FOLLOW-UP
The assessment does not end when the treatment session is completed.
Clinical follow-up makes it possible to evaluate:
✔ the progress of epidermal renewal;
✔ patient tolerance;
✔ the clinical response achieved;
✔ the need to modify the treatment protocol;
✔ planning of the next session.
Each follow-up visit provides valuable information for personalising treatment.
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CLINICAL DOCUMENTATION
It is recommended that every procedure is documented by recording:
✔ updated medical history;
✔ informed consent where appropriate;
✔ standardised clinical photographs;
✔ concentration used;
✔ exposure time;
✔ observed skin response;
✔ home care recommendations.
Comprehensive documentation facilitates patient follow-up and improves therapeutic continuity.
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PROFESSIONAL CHECKLIST
Before concluding the treatment session, confirm that:
☐ A pre-treatment clinical assessment was performed.
☐ The skin was correctly prepared.
☐ The peel was applied uniformly.
☐ The skin response was monitored throughout the procedure.
☐ Neutralisation was carried out.
☐ Post-treatment care was applied.
☐ The patient received home care instructions.
☐ The next clinical review was scheduled.
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GOOD CLINICAL PRACTICE
The application of Glycolic Peel 50% should form part of professional practice based on:
✔ individualised diagnosis;
✔ personalised protocols;
✔ continuous clinical observation;
✔ rigorous documentation;
✔ progressive follow-up;
✔ continuous improvement of treatment.
These principles make it possible to provide safer, more consistent procedures focused on sustainable results.
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THERAPDERMA CONCLUSION
The professional application of Glycolic Peel 50% requires far more than correct technique.
It demands rigorous clinical assessment, individualised planning and continuous observation of each patient’s biological response.
At TherapDerma, we understand that excellence depends not only on the product itself, but also on the professional’s ability to integrate scientific knowledge, clinical experience and structured protocols within an aesthetic medicine approach based on safety, personalisation and continuous improvement.

Clinical Protocols

Personalised protocols for intensive epidermal renewal
TherapDerma Glycolic Peel 50% may be incorporated into different aesthetic medicine programmes according to the clinical diagnosis, skin characteristics and established therapeutic objectives.
There is no universal protocol suitable for every patient. Each treatment should be individually designed, adapting the intensity, the frequency of sessions and the combination with other professional solutions.
Personalised planning constitutes one of the fundamental principles of the TherapDerma Clinical Ecosystem™.
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INTENSIVE EPIDERMAL RENEWAL PROTOCOL
Objective
To promote more intensive chemical exfoliation in order to progressively improve the superficial quality of the skin.
Ideal Patient
✔ Photoaged skin.
✔ Irregular skin texture.
✔ Loss of radiance.
✔ Thickened or devitalised skin.
Protocol Structure
Session 1
Clinical assessment + Glycolic Peel 50%

Subsequent Sessions
Reassessment + repeat treatment according to the clinical evolution

Final Phase
Assessment of results and maintenance planning.
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ANTI-AGEING PROTOCOL
Objective
To integrate Glycolic Peel 50% into programmes designed to improve the overall appearance of mature skin.
May be combined with
✔ Revitalising mesotherapy.
✔ Non-cross-linked hyaluronic acid.
✔ Skin biostimulation.
✔ Radiofrequency.
✔ LED therapy.
The treatment sequence should always be adapted according to the professional’s clinical judgement.
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GLOW SKIN PROTOCOL
Objective
To restore skin with a brighter, more even and revitalised appearance.
This protocol is particularly suitable when the patient presents dull skin, loss of freshness and reduced superficial skin quality.
The professional may complement the treatment with revitalising solutions and personalised home care to enhance the continuity of the results.
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SKIN TEXTURE IMPROVEMENT PROTOCOL
Objective
To promote a more homogeneous skin surface through progressive epidermal renewal.
It may be incorporated into patients presenting with:
✔ irregular skin texture;
✔ visible pores;
✔ rough skin;
✔ minor superficial irregularities.
The clinical evolution should be assessed regularly in order to adapt the protocol according to the response obtained.
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PHOTOAGEING PROTOCOL
Objective
To progressively improve the appearance of skin affected by the cumulative effects of sun exposure.
The treatment plan may include several sessions performed at regular intervals, combined with daily photoprotection and a personalised home care programme adapted to the patient’s needs.
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THERAPDERMA COMBINATION PROTOCOL
The integrated TherapDerma approach makes it possible to combine Glycolic Peel 50% with other professional solutions within the same therapeutic programme.
Illustrative Example
Phase 1
Glycolic Peel 50%

Phase 2
Personalised mesotherapy according to the clinical diagnosis

Phase 3
Complementary medical-aesthetic technology

Phase 4
Professional home care cosmetics

Clinical Follow-up
Reassessment and personalised maintenance.
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MAINTENANCE PLANNING
Once the clinical objectives have been achieved, the professional may establish a maintenance programme adapted to the characteristics of each patient.
Maintenance may include:
✔ periodic epidermal renewal sessions;
✔ scheduled clinical reviews;
✔ updating the home care programme;
✔ adaptation of the protocol according to the skin’s evolution.
This strategy promotes the continuity of results and makes it possible to respond to the physiological changes that occur over time.
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PROTOCOL PERSONALISATION
The intensity of treatment should never depend solely on the concentration of the peel.
Factors such as age, phototype, skin quality, previous aesthetic history and the response observed during previous sessions should all form part of the clinical planning.
Personalisation makes it possible to optimise results while maintaining a high level of safety throughout the treatment.
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PROTOCOL SUMMARY
Glycolic Peel 50% may be incorporated into programmes for:
✔ Intensive epidermal renewal.
✔ Skin rejuvenation.
✔ Texture improvement.
✔ Photoageing.
✔ Glow Skin protocols.
✔ TherapDerma combination treatments.
✔ Personalised maintenance programmes.
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THERAPDERMA CONCLUSION
The true potential of Glycolic Peel 50% is achieved when it forms part of a carefully planned clinical protocol.
The combination of diagnosis, personalisation, follow-up and complementary therapies makes it possible to develop treatments adapted to the individual needs of each patient, reinforcing an aesthetic medicine model based on progression, safety and professional excellence.

TherapDerma™ Combinations

Integrated protocols to enhance skin quality
Modern aesthetic medicine is based on the intelligent combination of different treatments that act in a complementary way on each patient’s specific needs.
Within this context, TherapDerma Glycolic Peel 50% may be integrated into personalised protocols together with mesotherapy, medical-aesthetic technologies and professional skincare, making it possible to develop more comprehensive, progressive programmes adapted to the clinical diagnosis.
The selection of each combination will always depend on the professional assessment and the established therapeutic objectives.
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GLYCOLIC PEEL 50% + REVITALISING MESOTHERAPY
Renewal + revitalisation
Following appropriate clinical planning, Glycolic Peel 50% may be combined with mesotherapy treatments designed to improve hydration, radiance and the overall quality of the skin.
Depending on the clinical diagnosis, the professional may select formulations aimed at:
✔ skin revitalisation;
✔ intensive hydration;
✔ anti-ageing programmes;
✔ improvement of skin quality;
✔ progressive regeneration protocols.
The combination should always be performed following the clinical sequence established by the professional.
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GLYCOLIC PEEL 50% + HYALURONIC ACID
Renewal + hydration
Controlled epidermal renewal may be complemented with non-cross-linked hyaluronic acid protocols when the therapeutic objective includes improving skin hydration and enhancing the overall appearance of the skin.
The sequential integration of both treatments forms part of personalised protocols based on the patient’s clinical assessment.
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GLYCOLIC PEEL 50% + SKIN BIOSTIMULATION
Renewal + biological stimulation
In selected patients, Glycolic Peel 50% may be incorporated into programmes that also include skin biostimulation techniques.
This combination should always respect the treatment sequence established by the professional and the physiological recovery time required between procedures.
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GLYCOLIC PEEL 50% + RADIOFREQUENCY
Renewal + medical-aesthetic technology
Radiofrequency may be incorporated into combination programmes designed to improve the overall quality of the skin.
Treatment planning should define the most appropriate sequence for integrating both procedures, always according to the patient’s diagnosis and clinical evolution.
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GLYCOLIC PEEL 50% + LED THERAPY
Renewal + photobiomodulation
LED Therapy may form part of personalised protocols in which the professional considers it appropriate to complement epidermal renewal with photobiomodulation techniques.
Its incorporation will always depend on the therapeutic objectives and the treatment strategy established.
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GLYCOLIC PEEL 50% + PROFESSIONAL HOME CARE
Clinical continuity at home
Professional treatment does not end at the clinic.
Personalised home care plays a fundamental role in maintaining skin quality and supporting the continuity of the results achieved through the professional protocol.
The selection of home care products should always be adapted to the patient’s needs and integrated into the overall treatment plan.
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THERAPDERMA CLINICAL ECOSYSTEM™
The true value of combination protocols lies in integrating different therapeutic tools within a coherent clinical strategy.
The TherapDerma Clinical Ecosystem™ enables professionals to combine:
✔ Chemical peels.
✔ Personalised mesotherapy.
✔ Medical-aesthetic technologies.
✔ Professional home care.
✔ Scheduled clinical follow-up.
This integrated approach promotes progressive, consistent and personalised treatments.
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EXAMPLE OF AN INTEGRATED PROTOCOL
Phase 1
Clinical assessment

Phase 2
Glycolic Peel 50%

Phase 3
Personalised complementary treatment

Phase 4
Professional home care

Phase 5
Clinical follow-up and protocol adaptation
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KEY PRINCIPLES OF COMBINATION THERAPY
✔ Individual clinical diagnosis.
✔ Personalised treatment planning.
✔ Correct treatment sequencing.
✔ Respect for skin physiology.
✔ Continuous clinical reassessment.
✔ Progressive adaptation of the protocol.
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SUMMARY OF COMBINATIONS
Glycolic Peel 50% may be integrated with:
✔ Revitalising mesotherapy.
✔ Non-cross-linked hyaluronic acid.
✔ Skin biostimulation.
✔ Radiofrequency.
✔ LED Therapy.
✔ Professional home care.
✔ Personalised combination protocols.
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THERAPDERMA CONCLUSION
The true therapeutic potential of Glycolic Peel 50% is enhanced when it forms part of an integrated treatment strategy.
The combination of chemical peels with personalised mesotherapy, medical-aesthetic technologies and professional home care enables the development of more comprehensive protocols adapted to each patient’s needs, reinforcing the scientific, progressive and personalised philosophy of the TherapDerma Clinical Ecosystem™.

Frequently Asked Questions (FAQ)

Clear answers for safer clinical practice
TherapDerma Glycolic Peel 50% is a professional chemical peel designed to be integrated into personalised epidermal renewal protocols.
Below, we answer some of the most frequently asked questions professionals raise before incorporating this treatment into their clinical practice.
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What type of peel is Glycolic Peel 50%?
Glycolic Peel 50% is a professional chemical peel formulated with 50% Glycolic Acid, belonging to the Alpha Hydroxy Acid (AHA) family.
It has been designed to promote intensive epidermal renewal through controlled chemical exfoliation, always within protocols performed by qualified professionals.
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What is the difference between Glycolic Peel 20%, 35% and 50%?
All three concentrations form part of the TherapDerma Clinical Ladder™.
The choice does not depend solely on the percentage of Glycolic Acid, but also on the diagnosis, the condition of the skin, the patient’s tolerance and the treatment objectives.
Each concentration occupies a specific position within a progressive epidermal renewal protocol.
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Is it necessary to neutralise the peel?
Yes.
As this is a peel based on Glycolic Acid, neutralisation forms part of the professional procedure and allows the action of the acid to be stopped once the planned exposure time has been reached.
This step is essential to maintain control throughout the treatment.
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How many treatment sessions are usually recommended?
There is no universal number of treatment sessions.
Planning will depend on the diagnosis, the skin response and the established clinical objectives.
Treatments are generally carried out through progressive programmes with regular reassessments between sessions.
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Can it be combined with other treatments?
Yes.
Glycolic Peel 50% may be integrated into combination protocols together with mesotherapy, radiofrequency, LED phototherapy, hyaluronic acid and other professional solutions whenever justified by the clinical diagnosis.
The combination should always be planned by the responsible professional.
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Does it cause visible peeling?
The response varies according to each patient and the protocol applied.
Some individuals experience very mild exfoliation, while others develop more noticeable peeling during the days following treatment.
The intensity of desquamation does not necessarily determine the clinical effectiveness of the peel.
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Can it be performed at any time of the year?
The treatment may be performed whenever the professional considers that the clinical conditions are appropriate and the patient is able to comply strictly with the recommended photoprotection measures.
In situations involving high sun exposure, the decision to initiate or postpone the protocol should be assessed individually.
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What post-treatment care should the patient follow?
After the peel, it is recommended to:
✔ use a broad-spectrum sunscreen every day;
✔ maintain adequate skin hydration;
✔ avoid manipulating the skin during the renewal process;
✔ follow the recommendations provided by the professional;
✔ attend all scheduled follow-up appointments.
Compliance with these recommendations promotes appropriate recovery.
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Who may apply Glycolic Peel 50%?
This product is intended exclusively for professionals trained in chemical peels and experienced in aesthetic medicine or professional aesthetics, in accordance with the legislation in force in each country.
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How should the product be stored?
It is recommended that the product is stored:
✔ tightly closed;
✔ protected from direct light;
✔ in a cool, dry place;
✔ away from extreme temperatures;
✔ always following the manufacturer’s instructions.

QUICK SUMMARY
Key Points
✔ Professional use only.
✔ Neutralisation is mandatory.
✔ Personalised protocols.
✔ Daily photoprotection is essential.
✔ Compatible with combination treatments.
✔ Requires prior clinical assessment.
✔ Integrated within the TherapDerma Clinical Ecosystem™.
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THERAPDERMA CONCLUSION
Answering the most frequently asked questions helps professionals to better understand the behaviour of Glycolic Peel 50% and facilitates clearer communication with patients.
At TherapDerma, we believe that providing accurate information, together with a precise diagnosis and personalised protocols, forms the foundation for developing safe, reproducible treatments aimed at achieving high-quality clinical results.

Discover other solutions within the TherapDerma Clinical Ecosystem™
Glycolic Peel 50% forms part of a comprehensive range of chemical peels, clinical protocols and professional resources developed by TherapDerma to help professionals design personalised, diagnosis-based treatment programmes.
If you would like to expand your knowledge or identify the most appropriate solution for other clinical needs, we recommend exploring the following resources.
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THERAPDERMA CHEMICAL PEELS
Glycolic Peel 20%
The ideal option for initiating progressive epidermal renewal protocols and preparing the skin before higher-intensity treatments.
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Glycolic Peel 35%
Recommended for advanced superficial exfoliation protocols, progressively improving skin texture, radiance and overall skin quality.
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Mandelic Peel
Particularly recommended for sensitive skin or skin with lower tolerance to other Alpha Hydroxy Acids, providing progressive and well-controlled exfoliation.
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Lactic Peel
Developed for protocols intended for dry, dull skin or skin requiring improved comfort and superficial hydration.
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Salicylic Peel
A professional solution for protocols designed for oily skin, excess sebum and acne-prone conditions.
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Phytic Peel
Integrated into programmes aimed at improving skin tone uniformity and complementing personalised depigmentation protocols.
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PR360 Specialty Peel™
A next-generation professional peel designed for specific advanced epidermal renewal protocols within the TherapDerma Clinical Ecosystem™.
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THERAPDERMA CLINICAL GUIDES
TherapDerma Clinical Decision Guide™
A practical guide to help professionals select the most appropriate peel and protocol according to the diagnosis, skin type and treatment objectives.
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Clinical Protocol Handbook™
A clinical manual containing structured protocols, application recommendations and therapeutic combination strategies for different aesthetic indications.
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PROFESSIONAL TRAINING
TherapDerma Professional Academy™
Scientific training programmes designed to provide deeper knowledge of:
✔ skin diagnosis;
✔ chemical peels;
✔ combination protocols;
✔ clinical planning;
✔ protocol-based aesthetic medicine.
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HOME CARE
TherapDerma Home Care™
Treatment continuity is essential for maintaining and optimising the results achieved in the clinic.
TherapDerma Home Care protocols have been developed to complement professional treatments and support skin quality between treatment sessions.
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AN ECOSYSTEM DESIGNED FOR PROFESSIONALS
All TherapDerma products, protocols and resources have been created to work together in a complementary way.
This approach enables professionals to develop more personalised, structured treatments focused on the progressive improvement of skin quality, while facilitating the integration of different solutions within a single therapeutic strategy.
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RESOURCES YOU MAY FIND USEFUL
✔ Glycolic Peel 20%
✔ Glycolic Peel 35%
✔ Mandelic Peel
✔ Lactic Peel
✔ Salicylic Peel
✔ Phytic Peel
✔ PR360 Specialty Peel™
✔ TherapDerma Clinical Decision Guide™
✔ Clinical Protocol Handbook™
✔ TherapDerma Professional Academy™
✔ TherapDerma Home Care™
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THERAPDERMA CONCLUSION
The TherapDerma Clinical Ecosystem™ brings together chemical peels, clinical protocols, specialised training and complementary solutions designed to support professionals at every stage of treatment.
Exploring these resources expands therapeutic possibilities, facilitates clinical decision-making and enables the development of personalised protocols based on a scientific, progressive approach focused on professional excellence.

TherapDerma Professional Academy™

Knowledge transforms treatments into results
In aesthetic medicine, the quality of a treatment does not depend solely on the formulation used.
Diagnosis, clinical planning, application technique and the continuous professional development of the practitioner are determining factors in achieving safe, reproducible and personalised results.
For this reason, TherapDerma Professional Academy™ was created to support the scientific and clinical development of aesthetic medicine professionals through training based on evidence, experience and clinical practice.
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TRAINING FOCUSED ON CLINICAL PRACTICE
TherapDerma training has been designed to facilitate the practical application of knowledge in the professional’s daily work.
Each programme combines scientific foundations with structured clinical protocols, enabling professionals to understand not only how to use a product, but also when to choose it, how to combine it and how to integrate it into a personalised treatment plan.
Our goal is to transform knowledge into better clinical decisions.
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AREAS OF TRAINING
TherapDerma Professional Academy™ develops specialised educational content across different areas of professional aesthetic medicine.
These include:
✔ Professional chemical peels.
✔ Advanced skin diagnosis.
✔ Facial rejuvenation protocols.
✔ Depigmentation treatments.
✔ Regenerative aesthetic medicine.
✔ Facial and body mesotherapy.
✔ Skin biostimulation.
✔ Combination of medical-aesthetic technologies.
✔ Planning of personalised treatment protocols.
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LEARNING METHODOLOGY
Our training programmes follow a progressive methodology combining:
Scientific Foundations
Understanding skin physiology and the principles underlying each treatment.

Clinical Application
Development of protocols adapted to different aesthetic indications.

Practical Case Studies
Clinical interpretation and therapeutic planning.

Continuous Updating
Integration of new scientific evidence, techniques and trends in aesthetic medicine.
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AVAILABLE RESOURCES
Professionals who are part of the TherapDerma Ecosystem™ have access to a wide range of support materials, including:
✔ Technical manuals.
✔ Clinical protocols.
✔ Treatment selection guides.
✔ Scientific documentation.
✔ Audiovisual material.
✔ Digital resources.
✔ Regular content updates.
These resources have been developed to support clinical decision-making and improve consistency in professional practice.
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CONTINUOUS LEARNING
Aesthetic medicine is constantly evolving.
New research, technologies and treatment protocols require professionals to remain continuously up to date.
TherapDerma considers continuous education to be a strategic tool for improving the quality of care, optimising clinical outcomes and strengthening patient confidence.
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A COMMUNITY OF PROFESSIONALS
TherapDerma Professional Academy™ promotes the exchange of knowledge among professionals who share the same vision of aesthetic medicine.
Collaborative learning, scientific updates and the sharing of clinical experience contribute to enriching professional practice and driving continuous improvement.
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WHY TRAIN WITH THERAPDERMA?
Because high-quality education enables professionals to:
✔ improve diagnostic skills;
✔ select treatments with greater precision;
✔ design personalised protocols;
✔ integrate different therapeutic solutions;
✔ optimise the patient experience;
✔ work with greater safety and confidence.
Training is a direct investment in professional excellence.
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THERAPDERMA PROFESSIONAL ACADEMY™
Learn · Evolve · Innovate
Our commitment is to provide professionals with the tools that enable them to grow alongside modern aesthetic medicine by integrating scientific knowledge, clinical experience and structured protocols within a single educational model.
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THERAPDERMA CONCLUSION
At TherapDerma, we believe that the best treatments are born from knowledge.
For this reason, TherapDerma Professional Academy™ supports professionals far beyond the product itself, providing continuous education, scientific resources and clinical protocols that help develop safer, more personalised aesthetic medicine based on professional excellence.

TherapDerma Clinical Decision System™

Transforming scientific knowledge into clinical decisions
Modern aesthetic medicine requires much more than simply understanding the properties of a product.
Every treatment begins with a clinical decision based on diagnosis, skin assessment and the selection of the most appropriate protocol for each patient.
For this reason, TherapDerma has developed a working model that helps professionals transform scientific knowledge into structured, consistent clinical decisions focused on achieving predictable results.
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A PROCESS BASED ON DIAGNOSIS
Every treatment should begin with an individual clinical assessment.
Before selecting a chemical peel, it is essential to evaluate a number of variables that will influence the planning of the treatment protocol.
These include:
✔ skin characteristics;
✔ phototype;
✔ epidermal thickness;
✔ degree of photoageing;
✔ previous treatments;
✔ skin tolerance;
✔ the patient’s therapeutic objectives.
The quality of the diagnosis determines the quality of the treatment.
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THE IMPORTANCE OF SELECTION
At TherapDerma, we believe there is no such thing as the “best” peel.
There is a peel that is most appropriate for each stage of the patient’s clinical evolution.
For this reason, each concentration of Glycolic Acid occupies a specific position within the TherapDerma Clinical Ladder™, making it possible to develop progressive treatments adapted to the biological response of the skin.
Selecting the correct concentration is one of the fundamental pillars of personalised aesthetic medicine.
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FROM DIAGNOSIS TO THE PROTOCOL
The clinical decision-making process can be summarised as a logical sequence:
Patient Assessment

Skin Diagnosis

Peel Selection

Protocol Planning

Professional Application

Clinical Follow-up

Maintenance Programme
Each of these stages has a direct influence on the quality of the final result.
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DECISIONS BASED ON CLINICAL EVOLUTION
The skin’s response should never be assessed only at the end of a treatment session.
The clinical evolution observed during the days that follow provides essential information for adapting treatment intensity, modifying the initial treatment plan and determining the next stage of the protocol.
Modern aesthetic medicine is based on dynamic clinical decisions rather than rigid treatments.
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THE THERAPDERMA CLINICAL DECISION SYSTEM™
The TherapDerma Clinical Decision System™ is based on five fundamental pillars:
✔ Accurate clinical diagnosis.
✔ Correct selection of the professional treatment.
✔ Personalised protocol planning.
✔ Continuous clinical monitoring.
✔ Progressive adaptation according to the patient’s response.
This methodology promotes more predictable, safer and more personalised treatments.
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THE VALUE OF CLINICAL PLANNING
Correct planning allows the professional to:
✔ optimise treatment sequencing;
✔ avoid unnecessarily aggressive procedures;
✔ improve treatment consistency;
✔ personalise every stage of the protocol;
✔ achieve progressive and sustainable clinical results.
Planning is as important as the treatment itself.
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CLINICAL DECISION FLOW
Clinical Assessment

Diagnosis

Selection of Glycolic Peel Concentration

Personalised Treatment Protocol

Professional Application

Clinical Reassessment

Treatment Adjustment

Maintenance Strategy
This continuous cycle allows the treatment to evolve according to the patient’s clinical progress.
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WHY DOES THIS SYSTEM MAKE A DIFFERENCE?
The TherapDerma Clinical Decision System™ helps professionals:
✔ make better clinical decisions;
✔ personalise treatments;
✔ increase treatment predictability;
✔ improve patient safety;
✔ integrate different TherapDerma solutions within the same therapeutic programme.
The objective is not simply to perform treatments, but to build structured therapeutic strategies.
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THERAPDERMA PHILOSOPHY
At TherapDerma, we believe that every successful treatment begins long before the product is applied.
It begins with a correct diagnosis, intelligent planning and a structured clinical methodology that allows professionals to adapt every decision to the biological characteristics of each patient.
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THERAPDERMA CONCLUSION
The TherapDerma Clinical Decision System™ transforms scientific knowledge into practical clinical decision-making.
By integrating diagnosis, protocol planning, continuous reassessment and personalised adaptation, it enables professionals to develop safer, more consistent and scientifically based treatments, reinforcing the philosophy of excellence that defines the TherapDerma Clinical Ecosystem™

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